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The map label for this gene is aroC

Identifier: 78222196

GI number: 78222196

Start: 1085509

End: 1086690

Strand: Direct

Name: aroC

Synonym: Gmet_0976

Alternate gene names: 78222196

Gene position: 1085509-1086690 (Clockwise)

Preceding gene: 78222195

Following gene: 78222197

Centisome position: 27.16

GC content: 65.06

Gene sequence:

>1182_bases
ATGCTCCGCTACCTGACCGCCGGCGAATCCCACGGCCCGCAACTGACGGCCATCATCGAGGGAATTCCCGCAGGCCTGAA
AATTTCCGAAGAAACCATCAACGTGGATCTGGCCCGCCGGCAGGGGGGCTACGGCCGTGGGGGCCGGATGCTCATCGAGA
AGGATCAGGTCCAGATCCTCTCCGGGGTCCGGTGGGGTGAGACCATCGGTTCCCCTGTGACCCTCTGCGTGGTGAACCGC
GACTGGGTTAACTGGCAGGAGAAGATGTCGCCCCACGAGCGCCACCGGGATGATAAGATCCGCGTCACCCGTTCGCGTCC
CGGCCATGCCGACCTTCCCGGAGCCATGAAGTATAACCACCGCGACGTCCGTAACATCCTGGAGCGTTCCAGCGCCCGGG
AGACTGCCATGCGGGTGGCGGTGGGCTCCGTTGCCCGGGCATTTCTGGCCTCCTTTGGTGTCACGGTGAGCGGCTTCGTG
GTGGAACTCGGGGGGATAAAGGCCGAGCGGCGTGGCCTCTCCTCCGACCGGCTCCGGGAACTGGCTGCCAAGTCCGAACT
TGCCACCTACGACCCCGAGGCGGAAGCGCGGATGAAGGCTTTTATCGACTCGGTGAAGGATGCCGGCGACACGGCGGGCG
GGGTCGTTGAGGTGGTTGTGACGGGAGCCCCGGTGGGACTCGGCAGCCACGTCCAGTGGGATCGCAAACTCGACGCCCGC
CTCGCCATGGCGGTCATGAGCATCCAGGCCATCAAGGGGGTCGAGATCGGCCTCGGCTTCGAGACGGCCCGCCGCCCCGG
CTCCCAGGTTCATGACGAGATCTACTTCGACTCCTCCCGCATCGCCCACGGTGAGGCCACGGGATTTTTCCGCAAGACCA
ACAATGCCGGAGGCATCGAGGGGGGGATCACCAACGGCGAGGAGATCGTCATCCGCGCGGCCATGAAGCCGATCCCGACC
CTCTACAAACCCCTCAGTTCGGTGGATATGCTCACCAAGGAGCCCTTCGAGGCCACGGTAGAGCGCTCCGATGTCTGCGC
CGTGCCCGCCGCCGCCGTGGTGGCCGAGTCGGTGGTGGCCATCGAGATTGCCAGCGCGTTCCTGGAGAAGTTCGGTGGCG
ACTCCCTTGCCGAGATACGGCGCAACTACGATGGCTACCTCGACTATCTCCGCTCCTTCTAG

Upstream 100 bases:

>100_bases
CATTACTCCTAAAATCGTTCTGTAATGAACAGGGTTCCATAAAGACAATTTTTACCATGCCAGGGGTATCCCCTGGCATT
TCTTTACTAAAGAGGTGAGT

Downstream 100 bases:

>100_bases
CGTGCGCAACGTCATTCTCACCGGCTTCATGGGGACGGGAAAAAGCAGCGTCGGCAGGCTTCTGGCCCATCGGCTCGGCT
TCCGCTACTGCGACCTGGAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQILSGVRWGETIGSPVTLCVVNR
DWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNHRDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFV
VELGGIKAERRGLSSDRLRELAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIEGGITNGEEIVIRAAMKPIPT
LYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVAIEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF

Sequences:

>Translated_393_residues
MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQILSGVRWGETIGSPVTLCVVNR
DWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNHRDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFV
VELGGIKAERRGLSSDRLRELAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIEGGITNGEEIVIRAAMKPIPT
LYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVAIEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF
>Mature_393_residues
MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQILSGVRWGETIGSPVTLCVVNR
DWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNHRDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFV
VELGGIKAERRGLSSDRLRELAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIEGGITNGEEIVIRAAMKPIPT
LYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVAIEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=371, Percent_Identity=36.9272237196765, Blast_Score=178, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=33.42175066313, Blast_Score=178, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_GEOMG (Q39X06)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383943.1
- HSSP:   P63611
- ProteinModelPortal:   Q39X06
- SMR:   Q39X06
- STRING:   Q39X06
- GeneID:   3738217
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0976
- NMPDR:   fig|269799.3.peg.1051
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   GMET269799:GMET_0976-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42697; Mature: 42697

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQIL
CCEEEECCCCCCCEEEEEECCCCCCCEECHHHEEEEEHHCCCCCCCCCCEEEEHHHHHHH
SGVRWGETIGSPVTLCVVNRDWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNH
HCCCCCHHCCCCEEEEEECCCCCCHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
RDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFVVELGGIKAERRGLSSDRLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCHHHHHH
LAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
LAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIE
HHHHHHHHHHHCCEEEECCHHHHCCCCCHHHHHHEECCCCCCCCCCCCEEEECCCCCCCC
GGITNGEEIVIRAAMKPIPTLYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVA
CCCCCCHHEEEEEHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHH
IEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF
HHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQIL
CCEEEECCCCCCCEEEEEECCCCCCCEECHHHEEEEEHHCCCCCCCCCCEEEEHHHHHHH
SGVRWGETIGSPVTLCVVNRDWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNH
HCCCCCHHCCCCEEEEEECCCCCCHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
RDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFVVELGGIKAERRGLSSDRLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCHHHHHH
LAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
LAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIE
HHHHHHHHHHHCCEEEECCHHHHCCCCCHHHHHHEECCCCCCCCCCCCEEEECCCCCCCC
GGITNGEEIVIRAAMKPIPTLYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVA
CCCCCCHHEEEEEHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHH
IEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF
HHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA