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The map label for this gene is paaK [H]

Identifier: 78222170

GI number: 78222170

Start: 1053762

End: 1055063

Strand: Direct

Name: paaK [H]

Synonym: Gmet_0950

Alternate gene names: 78222170

Gene position: 1053762-1055063 (Clockwise)

Preceding gene: 78222169

Following gene: 78222171

Centisome position: 26.36

GC content: 65.67

Gene sequence:

>1302_bases
ATGCTCACACGTTTTCCCGCCCCCTTTTCTTCCCCTGCCGACCTTGAACGGCTGCAGCTTGCCGGCGTGCAATGGACCGT
CGCCCACGCCTGGAACAACTCCCCCTTCTACCGGGAGCGGTTCCAGCAGGCCGGCGTCTCGCCGGAGGATATCCGCACCC
TCGACGACCTGCGCAGACTTCCCTTTACCACAGCCGATGACCTGCGGGCCGGCTATCCCTTTCCGCTCCGGTCGGCATCC
TTTGAGGAGATTGTCCGGATCCACTCATCATCCGGTACTACCGGCAAGAGGAAGATCCTCTGCTACACCCAGAAGGATCT
GGACGACTGGGCCCGGATGTTCTGCCGCTGCTACGAGCTGGCGGGGGTGACGCGGGAGGACCGGGTCCAGATCTGCGTCG
GCTACGGGCTCTGGACCGCTGGAATCGGCTTCCAGGCCGCCTGCGAGCGCTACGGCGCCCTGGCTGTGCCGGTGGGGCCG
GGGAACCTGGAACTCCAGACCACCTTCCTCACGGACGTCCAGTCCACGGTGGTCTGCTGCACCGCCTCCATGGGGCTGCT
CCTGGCGGAGGAAGTCCAGCGGCGGGGGCTCAGGGACCGGATAAAGGTCAGGAAGGTGATTCTCGGGGCCGAGCGCTCCA
GCGAGGCGATGCTCGCCAAAATCCGGGAGGGGCTCGGGGCGGAATCGGTTCACGATATCACCGGCCTCACCGAGGTCTAC
GGCCCCGGCACCGGCCTTTCCTGTGCCGCTCCGGGGGCAAACGGCGCCGTCCACTACTGGGCCGACTACTATCTCCTCGA
AATCCTTGATCCCGAAACCCTTCAGCCGGTGGCACCCGGGGAGGTGGGTGAGATGGTCTTCACGACCCTCCGCAAGGAGG
CGGCGCCCCTCATTCGCTACCGCTCCCGGGACCTCACCCGGCTGATCCCCGGTGACTGCCCTTGCGGCTGCACGTTCCCC
CGTCACGACCGGATTCTCGGCCGTTCCGACGACGTGGTCATCTTCCGCGGCGTCAACATCTACCCGGGGCAGATCGATGA
GATTCTCGATACCGTGGCGGGGGTCGGGAGCGAATTCCAGGTAGTTCTCGACCATGGCGCCGACGGCCGCGACTACATGA
CCATCCGCGTGGAGCGGGGCGAGGACGGTGCTCCGGCCGACGACCCGGCCCTTGCCCGAAAGGTCGCCTCTGCCGTCAAG
CACAGCCTCATGGTTTCCTGTGAGGTGGTTGTCCTCCCCTACGGCGAGCTCCCCCGCTCGGAGGGGAAGACCAGAAGGAT
GTATGACAACCGGAAGTACTAA

Upstream 100 bases:

>100_bases
CTGGTCGAGAAGGGGAAGCTGCGGGACGCTTCCCTGGCGGCCCTTCGTCTGGGGATGGAGAATGCAGCAGGCTGATTTTC
GTCCGGAGGTTTCATAAACG

Downstream 100 bases:

>100_bases
CGGTGCTCAACATGCAACGATTGCGTGACGACATACGTTGAACGCCAGACTCGACACGGATTCTGTTGAGCATTTCACCC
CTTTGTGCTACCGTTCTCCG

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLTRFPAPFSSPADLERLQLAGVQWTVAHAWNNSPFYRERFQQAGVSPEDIRTLDDLRRLPFTTADDLRAGYPFPLRSAS
FEEIVRIHSSSGTTGKRKILCYTQKDLDDWARMFCRCYELAGVTREDRVQICVGYGLWTAGIGFQAACERYGALAVPVGP
GNLELQTTFLTDVQSTVVCCTASMGLLLAEEVQRRGLRDRIKVRKVILGAERSSEAMLAKIREGLGAESVHDITGLTEVY
GPGTGLSCAAPGANGAVHYWADYYLLEILDPETLQPVAPGEVGEMVFTTLRKEAAPLIRYRSRDLTRLIPGDCPCGCTFP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDTVAGVGSEFQVVLDHGADGRDYMTIRVERGEDGAPADDPALARKVASAVK
HSLMVSCEVVVLPYGELPRSEGKTRRMYDNRKY

Sequences:

>Translated_433_residues
MLTRFPAPFSSPADLERLQLAGVQWTVAHAWNNSPFYRERFQQAGVSPEDIRTLDDLRRLPFTTADDLRAGYPFPLRSAS
FEEIVRIHSSSGTTGKRKILCYTQKDLDDWARMFCRCYELAGVTREDRVQICVGYGLWTAGIGFQAACERYGALAVPVGP
GNLELQTTFLTDVQSTVVCCTASMGLLLAEEVQRRGLRDRIKVRKVILGAERSSEAMLAKIREGLGAESVHDITGLTEVY
GPGTGLSCAAPGANGAVHYWADYYLLEILDPETLQPVAPGEVGEMVFTTLRKEAAPLIRYRSRDLTRLIPGDCPCGCTFP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDTVAGVGSEFQVVLDHGADGRDYMTIRVERGEDGAPADDPALARKVASAVK
HSLMVSCEVVVLPYGELPRSEGKTRRMYDNRKY
>Mature_433_residues
MLTRFPAPFSSPADLERLQLAGVQWTVAHAWNNSPFYRERFQQAGVSPEDIRTLDDLRRLPFTTADDLRAGYPFPLRSAS
FEEIVRIHSSSGTTGKRKILCYTQKDLDDWARMFCRCYELAGVTREDRVQICVGYGLWTAGIGFQAACERYGALAVPVGP
GNLELQTTFLTDVQSTVVCCTASMGLLLAEEVQRRGLRDRIKVRKVILGAERSSEAMLAKIREGLGAESVHDITGLTEVY
GPGTGLSCAAPGANGAVHYWADYYLLEILDPETLQPVAPGEVGEMVFTTLRKEAAPLIRYRSRDLTRLIPGDCPCGCTFP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDTVAGVGSEFQVVLDHGADGRDYMTIRVERGEDGAPADDPALARKVASAVK
HSLMVSCEVVVLPYGELPRSEGKTRRMYDNRKY

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=432, Percent_Identity=38.6574074074074, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47889; Mature: 47889

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRFPAPFSSPADLERLQLAGVQWTVAHAWNNSPFYRERFQQAGVSPEDIRTLDDLRRL
CCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
PFTTADDLRAGYPFPLRSASFEEIVRIHSSSGTTGKRKILCYTQKDLDDWARMFCRCYEL
CCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGVTREDRVQICVGYGLWTAGIGFQAACERYGALAVPVGPGNLELQTTFLTDVQSTVVCC
HCCCCCCCEEEEEECCHHHHCCCHHHHHHHCCCEEEEECCCCEEEEEEEHHHHHHHHHHH
TASMGLLLAEEVQRRGLRDRIKVRKVILGAERSSEAMLAKIREGLGAESVHDITGLTEVY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHCHHHHC
GPGTGLSCAAPGANGAVHYWADYYLLEILDPETLQPVAPGEVGEMVFTTLRKEAAPLIRY
CCCCCCEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RSRDLTRLIPGDCPCGCTFPRHDRILGRSDDVVIFRGVNIYPGQIDEILDTVAGVGSEFQ
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
VVLDHGADGRDYMTIRVERGEDGAPADDPALARKVASAVKHSLMVSCEVVVLPYGELPRS
EEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCC
EGKTRRMYDNRKY
CCCHHHCCCCCCC
>Mature Secondary Structure
MLTRFPAPFSSPADLERLQLAGVQWTVAHAWNNSPFYRERFQQAGVSPEDIRTLDDLRRL
CCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
PFTTADDLRAGYPFPLRSASFEEIVRIHSSSGTTGKRKILCYTQKDLDDWARMFCRCYEL
CCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGVTREDRVQICVGYGLWTAGIGFQAACERYGALAVPVGPGNLELQTTFLTDVQSTVVCC
HCCCCCCCEEEEEECCHHHHCCCHHHHHHHCCCEEEEECCCCEEEEEEEHHHHHHHHHHH
TASMGLLLAEEVQRRGLRDRIKVRKVILGAERSSEAMLAKIREGLGAESVHDITGLTEVY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHCHHHHC
GPGTGLSCAAPGANGAVHYWADYYLLEILDPETLQPVAPGEVGEMVFTTLRKEAAPLIRY
CCCCCCEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RSRDLTRLIPGDCPCGCTFPRHDRILGRSDDVVIFRGVNIYPGQIDEILDTVAGVGSEFQ
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
VVLDHGADGRDYMTIRVERGEDGAPADDPALARKVASAVKHSLMVSCEVVVLPYGELPRS
EEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCC
EGKTRRMYDNRKY
CCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]