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The map label for this gene is yqeV [H]

Identifier: 78222094

GI number: 78222094

Start: 962940

End: 964235

Strand: Direct

Name: yqeV [H]

Synonym: Gmet_0874

Alternate gene names: 78222094

Gene position: 962940-964235 (Clockwise)

Preceding gene: 78222093

Following gene: 78222098

Centisome position: 24.09

GC content: 66.51

Gene sequence:

>1296_bases
ATGCAGAGAGTGGCGATTTCAACCCTGGGTTGCAAGATCAACCAGTTCGAGTCGGCGGCCATGACCGAGAGCCTCGGTAG
GGAAGGGTTCCGGGTGGTCCCCTTTGACGAGGATGCCGACATTTACGTGATCAACACCTGCACGGTGACCGCGAAAACCG
ATGCCGAGTCGCGGCGCCTGATTCGTCGCGCCCTGCGCCGCAATCCCGCGGCCCGGGTGGTGGTGACCGGCTGCTACGCC
CAGGTGGCCCCCGATGCGGTGAAAGATCTTCCTGGCGTGGCTCTGGTGGTGGGGAATAGCGAGAAGCGGAGCATCGGCGA
GCTTTTGCGGGACGCTGCCCCGGCGGAAAAGGTCATGGTGTCGGACATTTCCCGGGAGCGGACCGCGGAGGGGCTCCGTC
TCGAAAGCTTTGCCGAGCATACCCGGGCCTTCCTCCAGGTCCAGAACGGGTGCGATGCCTTCTGCTCCTACTGCATCGTC
CCCTATGCCCGGGGGCGGAGCCGGAGCGTCTCCTTCAGCGAAGCCCTCGCAGGGATCAGGAACTTCGCCGCCCAGGGGTT
CCGGGAGGTGGTGCTGACCGGCATCCACCTGGGGGCCTACGGCCTTGACCTTGCCCCGCCGACGAACCTCCTGGCGCTTC
TGGAGGCCTCCGAGGCGGAAAAGGCGGTGCCGCGGCTCCGGGTCGGGTCGGTGGAGCCCAATGAACTGACCGACGCTCTC
GTTGATTTCCTGGCCCGGTCGGAGACGGTCTGCCCCCACCTCCACATCCCGCTCCAGAGCGGCGATGACCGGGTGCTCGA
ACGGATGGGGCGGCGCTACACGGCGGCGTTCTTCCGGGAACGGGTGGAACGGCTCGTGGCGGTGGTCCCCGACATCTTCA
TCGGCTGCGACGTCATTGCCGGTTTTCCGGGAGAGACTGACGAGGAGTTCCAGAACACCGTACGTCTCATCGAGGAACTG
CCGGTGGCCTCCCTCCACGTCTTCCCCTATTCCCGGCGGGAGGGGACGGCGGCTGCCCGGATGGAGGGACAGGTGGATGG
GAAGGTGATTCGCGGCCGGGCTGAGATCCTGAGGGAGGTTGGCGAGCGTAAGCGGCGCTCTTTCTGCGAGCGGTTCGTGG
GGCGTGAGCTGGCGGTCCTGATGCAGAACCGGGGCCGTGACGGCGAAGCTGTGGGGCTGTCGCGCAACTACCTGCCGGTC
CGGGTGCCCGGCTACGCAGGGGAGATGAACGCCGAGGCGACGGTCATGGTCACGGAGGTGACGCCGGACGGAGTGGGGGG
AATCATCCGAGGGTAA

Upstream 100 bases:

>100_bases
TCACGCCGGGGCAGGCGGTGGTCTTCTACCACGGTGACGAGGTGCTCGGTGGCGGTTGGATCGATGCGGCGATGACCGAG
GGGTAGCGGAAGAGGGATTC

Downstream 100 bases:

>100_bases
AGAAGAAGGTTGCACCCTTGCCCTCTTCTGCTTCGGCCCAGATTCTTCCCCCGTGGCGGTGAACGATCCGCTGGACCGTG
GCGAGCCCGATGCCGTTCCC

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MQRVAISTLGCKINQFESAAMTESLGREGFRVVPFDEDADIYVINTCTVTAKTDAESRRLIRRALRRNPAARVVVTGCYA
QVAPDAVKDLPGVALVVGNSEKRSIGELLRDAAPAEKVMVSDISRERTAEGLRLESFAEHTRAFLQVQNGCDAFCSYCIV
PYARGRSRSVSFSEALAGIRNFAAQGFREVVLTGIHLGAYGLDLAPPTNLLALLEASEAEKAVPRLRVGSVEPNELTDAL
VDFLARSETVCPHLHIPLQSGDDRVLERMGRRYTAAFFRERVERLVAVVPDIFIGCDVIAGFPGETDEEFQNTVRLIEEL
PVASLHVFPYSRREGTAAARMEGQVDGKVIRGRAEILREVGERKRRSFCERFVGRELAVLMQNRGRDGEAVGLSRNYLPV
RVPGYAGEMNAEATVMVTEVTPDGVGGIIRG

Sequences:

>Translated_431_residues
MQRVAISTLGCKINQFESAAMTESLGREGFRVVPFDEDADIYVINTCTVTAKTDAESRRLIRRALRRNPAARVVVTGCYA
QVAPDAVKDLPGVALVVGNSEKRSIGELLRDAAPAEKVMVSDISRERTAEGLRLESFAEHTRAFLQVQNGCDAFCSYCIV
PYARGRSRSVSFSEALAGIRNFAAQGFREVVLTGIHLGAYGLDLAPPTNLLALLEASEAEKAVPRLRVGSVEPNELTDAL
VDFLARSETVCPHLHIPLQSGDDRVLERMGRRYTAAFFRERVERLVAVVPDIFIGCDVIAGFPGETDEEFQNTVRLIEEL
PVASLHVFPYSRREGTAAARMEGQVDGKVIRGRAEILREVGERKRRSFCERFVGRELAVLMQNRGRDGEAVGLSRNYLPV
RVPGYAGEMNAEATVMVTEVTPDGVGGIIRG
>Mature_431_residues
MQRVAISTLGCKINQFESAAMTESLGREGFRVVPFDEDADIYVINTCTVTAKTDAESRRLIRRALRRNPAARVVVTGCYA
QVAPDAVKDLPGVALVVGNSEKRSIGELLRDAAPAEKVMVSDISRERTAEGLRLESFAEHTRAFLQVQNGCDAFCSYCIV
PYARGRSRSVSFSEALAGIRNFAAQGFREVVLTGIHLGAYGLDLAPPTNLLALLEASEAEKAVPRLRVGSVEPNELTDAL
VDFLARSETVCPHLHIPLQSGDDRVLERMGRRYTAAFFRERVERLVAVVPDIFIGCDVIAGFPGETDEEFQNTVRLIEEL
PVASLHVFPYSRREGTAAARMEGQVDGKVIRGRAEILREVGERKRRSFCERFVGRELAVLMQNRGRDGEAVGLSRNYLPV
RVPGYAGEMNAEATVMVTEVTPDGVGGIIRG

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=425, Percent_Identity=30.3529411764706, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI28872784, Length=403, Percent_Identity=28.0397022332506, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI28872782, Length=403, Percent_Identity=28.0397022332506, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1786882, Length=436, Percent_Identity=30.7339449541284, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787057, Length=403, Percent_Identity=26.5508684863524, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553146, Length=416, Percent_Identity=28.125, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71996771, Length=357, Percent_Identity=30.2521008403361, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356207, Length=451, Percent_Identity=27.9379157427938, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI19922432, Length=418, Percent_Identity=28.9473684210526, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47272; Mature: 47272

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVAISTLGCKINQFESAAMTESLGREGFRVVPFDEDADIYVINTCTVTAKTDAESRRL
CCCEEEHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEEEEEECCCHHHHHH
IRRALRRNPAARVVVTGCYAQVAPDAVKDLPGVALVVGNSEKRSIGELLRDAAPAEKVMV
HHHHHHCCCCCEEEEEECHHHHCCHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHH
SDISRERTAEGLRLESFAEHTRAFLQVQNGCDAFCSYCIVPYARGRSRSVSFSEALAGIR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NFAAQGFREVVLTGIHLGAYGLDLAPPTNLLALLEASEAEKAVPRLRVGSVEPNELTDAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHH
VDFLARSETVCPHLHIPLQSGDDRVLERMGRRYTAAFFRERVERLVAVVPDIFIGCDVIA
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GFPGETDEEFQNTVRLIEELPVASLHVFPYSRREGTAAARMEGQVDGKVIRGRAEILREV
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCEECCHHHHHHHH
GERKRRSFCERFVGRELAVLMQNRGRDGEAVGLSRNYLPVRVPGYAGEMNAEATVMVTEV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCEEEEEEEE
TPDGVGGIIRG
CCCCCCCCCCC
>Mature Secondary Structure
MQRVAISTLGCKINQFESAAMTESLGREGFRVVPFDEDADIYVINTCTVTAKTDAESRRL
CCCEEEHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEEEEEECCCHHHHHH
IRRALRRNPAARVVVTGCYAQVAPDAVKDLPGVALVVGNSEKRSIGELLRDAAPAEKVMV
HHHHHHCCCCCEEEEEECHHHHCCHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHH
SDISRERTAEGLRLESFAEHTRAFLQVQNGCDAFCSYCIVPYARGRSRSVSFSEALAGIR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NFAAQGFREVVLTGIHLGAYGLDLAPPTNLLALLEASEAEKAVPRLRVGSVEPNELTDAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHH
VDFLARSETVCPHLHIPLQSGDDRVLERMGRRYTAAFFRERVERLVAVVPDIFIGCDVIA
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GFPGETDEEFQNTVRLIEELPVASLHVFPYSRREGTAAARMEGQVDGKVIRGRAEILREV
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCEECCHHHHHHHH
GERKRRSFCERFVGRELAVLMQNRGRDGEAVGLSRNYLPVRVPGYAGEMNAEATVMVTEV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCEEEEEEEE
TPDGVGGIIRG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]