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The map label for this gene is sixA [C]

Identifier: 78222098

GI number: 78222098

Start: 967167

End: 967715

Strand: Direct

Name: sixA [C]

Synonym: Gmet_0878

Alternate gene names: 78222098

Gene position: 967167-967715 (Clockwise)

Preceding gene: 78222094

Following gene: 78222099

Centisome position: 24.19

GC content: 65.03

Gene sequence:

>549_bases
ATGCCGGAGGAGTCCCCGCGGGGCCTTCTCCGGGAAAGGAGAGGAAACGTGAAACTCTATCTGATCCGCCATGGGGAGGC
CGTCGAGCGGGGCGAGACGGTCCGGGAGGAGGACCGCTGGCTTACCGCCGTCGGGCGTGACGGGTTCCGGGCAAACGCCC
GACGTCTGGCAAAGAAGGTGGTCGCTCCCGAAGTAATCGTTACGAGTCCCCTGGTGCGGGCCGTGCAGACGGCCGATATC
CTCGCCGAGGTTCTCGGTTTTTCCGGCGAAGTCACCGTATCGCAGGAGCTGGCGCCGGGGTTCAGTTCAGAGGGGCTCTT
CCGCCTGGCAGGTGTCCGCGGATCGCCCCGGAGCCTGGCTGTGGTAGGGCACGAGCCCGACCTGGGTGAGGTTTTCGGTC
GGTTGTTGGGGCGCGACGGCGCGCTTCCCCTCAAAAAAGGGGCGATTGTGGCACTGAGGCTGGATTCGGCGGAGAGCGGA
ACGCCTGCCCGGTTCCTGTGGATGATTCAGCGGGGCAAGAAGTTTCGTGAACTTCCCGAACCCGGTTAA

Upstream 100 bases:

>100_bases
CGGTGAAAATACCCTCGGACCCGCAACAGGGGGGCAAGCGGCCATTGAAAACTCCCCGGGCTCTGTTTTACTTAACCAGC
GAAGGGAGCAGGTCGGCTGG

Downstream 100 bases:

>100_bases
GGTTCGGTGAAATTCGAAAATTTGACCGGCGCAGGGAAGGGGAAGCCCTTGACGATCACGGACGAAACGCCTCTCTGGGT
CGCAGCACCGGCGCTTCTGG

Product: phosphohistidine phosphatase, SixA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPEESPRGLLRERRGNVKLYLIRHGEAVERGETVREEDRWLTAVGRDGFRANARRLAKKVVAPEVIVTSPLVRAVQTADI
LAEVLGFSGEVTVSQELAPGFSSEGLFRLAGVRGSPRSLAVVGHEPDLGEVFGRLLGRDGALPLKKGAIVALRLDSAESG
TPARFLWMIQRGKKFRELPEPG

Sequences:

>Translated_182_residues
MPEESPRGLLRERRGNVKLYLIRHGEAVERGETVREEDRWLTAVGRDGFRANARRLAKKVVAPEVIVTSPLVRAVQTADI
LAEVLGFSGEVTVSQELAPGFSSEGLFRLAGVRGSPRSLAVVGHEPDLGEVFGRLLGRDGALPLKKGAIVALRLDSAESG
TPARFLWMIQRGKKFRELPEPG
>Mature_181_residues
PEESPRGLLRERRGNVKLYLIRHGEAVERGETVREEDRWLTAVGRDGFRANARRLAKKVVAPEVIVTSPLVRAVQTADIL
AEVLGFSGEVTVSQELAPGFSSEGLFRLAGVRGSPRSLAVVGHEPDLGEVFGRLLGRDGALPLKKGAIVALRLDSAESGT
PARFLWMIQRGKKFRELPEPG

Specific function: Exhibits Phosphohistidine Phosphatase Activity Towards The Hpt Domain Of The Arcb Sensor Involved In The Multistep His- Asp Phosphorelay. [C]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 19873; Mature: 19742

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEESPRGLLRERRGNVKLYLIRHGEAVERGETVREEDRWLTAVGRDGFRANARRLAKKV
CCCCCHHHHHHHCCCCEEEEEEECCCHHHHCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
VAPEVIVTSPLVRAVQTADILAEVLGFSGEVTVSQELAPGFSSEGLFRLAGVRGSPRSLA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCEEEEECCCCCCCEEE
VVGHEPDLGEVFGRLLGRDGALPLKKGAIVALRLDSAESGTPARFLWMIQRGKKFRELPE
EEECCCCHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHCCHHCCCCC
PG
CC
>Mature Secondary Structure 
PEESPRGLLRERRGNVKLYLIRHGEAVERGETVREEDRWLTAVGRDGFRANARRLAKKV
CCCCHHHHHHHCCCCEEEEEEECCCHHHHCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
VAPEVIVTSPLVRAVQTADILAEVLGFSGEVTVSQELAPGFSSEGLFRLAGVRGSPRSLA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCEEEEECCCCCCCEEE
VVGHEPDLGEVFGRLLGRDGALPLKKGAIVALRLDSAESGTPARFLWMIQRGKKFRELPE
EEECCCCHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHCCHHCCCCC
PG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]