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The map label for this gene is iscR [H]

Identifier: 78222091

GI number: 78222091

Start: 960223

End: 960651

Strand: Direct

Name: iscR [H]

Synonym: Gmet_0871

Alternate gene names: 78222091

Gene position: 960223-960651 (Clockwise)

Preceding gene: 78222090

Following gene: 78222092

Centisome position: 24.02

GC content: 63.87

Gene sequence:

>429_bases
ATGCGGCTTTCGACACGGGCACAGTATGCGGTTCGGGCCATGGTGGATCTTTCCCTCCACTCGGAGGGGAGACCGGTCTC
GCTCAAGGATATTGCCCTGCGGGAGGATATTCCCCTCAACTATCTGGAGCAGCTCTTCAACCGGCTGCGCCGCGGTGCCA
TCGTGGAGAGTGTGCGGGGACCCGGGGGAGGATACCTCCTGGCCCGGGAGAGTTCGGCAATCCGGGTGGGGGAGATCGTG
GCCACGGTTGAGGAACCCCTGACGCCGGTTTCGTGCATGGACAAGGGGAAGGGGCGTTGCACCCGGACGGCCGCCTGCAC
CACCCACAATGTCTGGGAGATGCTCGGCGAGCGGATCAGAACCTTTCTCGATTCCATTACCCTGGAGGACCTGGTAATCG
AGGCACGGGGGCGCGGAGGCGAGGAGTGA

Upstream 100 bases:

>100_bases
AGGTGGTTTCTTGCGGGGATCGGTTCTCCGCGAGAGCTCCGCCCCTTCCGGGAACCAGTGGTGGGAAAGGTGACAACGTA
GAAGGAGAAGAGGCTGATTT

Downstream 100 bases:

>100_bases
GGGCGGTATTGCCCGCATTTGAGACTGCATGATGATCTATCTGGACCACAATGCGACAACGCCGGTCCACCCTGATGTGG
TGGAGGCGTTGTTGCCGTTT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MRLSTRAQYAVRAMVDLSLHSEGRPVSLKDIALREDIPLNYLEQLFNRLRRGAIVESVRGPGGGYLLARESSAIRVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHNVWEMLGERIRTFLDSITLEDLVIEARGRGGEE

Sequences:

>Translated_142_residues
MRLSTRAQYAVRAMVDLSLHSEGRPVSLKDIALREDIPLNYLEQLFNRLRRGAIVESVRGPGGGYLLARESSAIRVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHNVWEMLGERIRTFLDSITLEDLVIEARGRGGEE
>Mature_142_residues
MRLSTRAQYAVRAMVDLSLHSEGRPVSLKDIALREDIPLNYLEQLFNRLRRGAIVESVRGPGGGYLLARESSAIRVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHNVWEMLGERIRTFLDSITLEDLVIEARGRGGEE

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=132, Percent_Identity=49.2424242424242, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1790621, Length=134, Percent_Identity=32.8358208955224, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15742; Mature: 15742

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSTRAQYAVRAMVDLSLHSEGRPVSLKDIALREDIPLNYLEQLFNRLRRGAIVESVRG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGGGYLLARESSAIRVGEIVATVEEPLTPVSCMDKGKGRCTRTAACTTHNVWEMLGERIR
CCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHH
TFLDSITLEDLVIEARGRGGEE
HHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRLSTRAQYAVRAMVDLSLHSEGRPVSLKDIALREDIPLNYLEQLFNRLRRGAIVESVRG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGGGYLLARESSAIRVGEIVATVEEPLTPVSCMDKGKGRCTRTAACTTHNVWEMLGERIR
CCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHH
TFLDSITLEDLVIEARGRGGEE
HHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA