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The map label for this gene is tyrC [H]

Identifier: 78222083

GI number: 78222083

Start: 952624

End: 953484

Strand: Direct

Name: tyrC [H]

Synonym: Gmet_0863

Alternate gene names: 78222083

Gene position: 952624-953484 (Clockwise)

Preceding gene: 78222082

Following gene: 78222084

Centisome position: 23.83

GC content: 61.44

Gene sequence:

>861_bases
ATGCCCTTCATCCATAGATTAGCCATCATCGGCGTTGGCCTTATCGGCGGCTCCCTGGCCCGCATCCTGCGAGAGAAGGG
GGCGGTGGGGGAGATTGTCGGAATCGGGCGCGGCGAAGCAAACCTGCGCAAGGCGGTGGAACTTGGGGTTATCGATCGGT
ACTCCCTGGATTCCGTAGCCGGCGTCGAGGGTGCTGACGTCGTTTTCCTGGCCACGCCGGTCTGCTCCATTCCTTCCATA
ACGGCCGAGATTGCCCCCCATCTGGCTCCCGGTTGCGTGGTGACCGACGGGGGGAGCGTGAAGGAAGAGATTGTTTCCGC
CTGCGAACCCCTCATGCCGAACGGGATTCATTTCGTCGGCGGGCACCCCATCGCCGGCACCGAGCACTCGGGTGTGGAAG
CGTCGTTTTCCTCCCTCTATGTGGGAAAGCGCTGCATCGTGACCCCTACCTCCCGTACCAGCCAGGATGCCCTTGCCAAG
GTGGTGCGGATGTGGGAGGTCGCCGGTTCCGAAGTGGTCATCATGGATACGGAGAAGCACGACCGGGTGCTTGCGGCCAT
TTCCCATCTCCCCCACATGGTTGCCTATGCTCTGGTGAATGCCGTTGAAGGGTACGACCGCTTCGAGGAGAGTATCCTTC
GCTACTCCGCCGGCGGGTTCCGCGACTTTACCCGGATAGCCTCGTCGGACCCGGCCATGTGGCGGGACATCGCCCTCATG
AATCGGGAAGCGGTCATCGAAATGATGGACCATTTTGCCGCATACTTTGCGAGACTCCGGGAGTTGGTGGCAGCGGCCGA
CGCCCCTGGACTCGAACGCTTCTTCCGGGAATCGAAGGAAAGCAGAGACGCTATTCTGTAG

Upstream 100 bases:

>100_bases
AGATCCGGTGGTGTCCGACGCGGTCCAGGAACTGAAGAACTACTGCCAGTTTGTCAAGATCCTCGGATCATACCCCCGGG
CGAAATAGCCGTTGGATACA

Downstream 100 bases:

>100_bases
GGAAGGCAGTTCCTAAATCTCAGCCAAGGTGGTTAATCGTGCAGAGCTATACCGTTCGGCCGGCCAAGGGGATTCGTGGC
GAGATCACCGTTCCCGGCGA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPFIHRLAIIGVGLIGGSLARILREKGAVGEIVGIGRGEANLRKAVELGVIDRYSLDSVAGVEGADVVFLATPVCSIPSI
TAEIAPHLAPGCVVTDGGSVKEEIVSACEPLMPNGIHFVGGHPIAGTEHSGVEASFSSLYVGKRCIVTPTSRTSQDALAK
VVRMWEVAGSEVVIMDTEKHDRVLAAISHLPHMVAYALVNAVEGYDRFEESILRYSAGGFRDFTRIASSDPAMWRDIALM
NREAVIEMMDHFAAYFARLRELVAAADAPGLERFFRESKESRDAIL

Sequences:

>Translated_286_residues
MPFIHRLAIIGVGLIGGSLARILREKGAVGEIVGIGRGEANLRKAVELGVIDRYSLDSVAGVEGADVVFLATPVCSIPSI
TAEIAPHLAPGCVVTDGGSVKEEIVSACEPLMPNGIHFVGGHPIAGTEHSGVEASFSSLYVGKRCIVTPTSRTSQDALAK
VVRMWEVAGSEVVIMDTEKHDRVLAAISHLPHMVAYALVNAVEGYDRFEESILRYSAGGFRDFTRIASSDPAMWRDIALM
NREAVIEMMDHFAAYFARLRELVAAADAPGLERFFRESKESRDAIL
>Mature_285_residues
PFIHRLAIIGVGLIGGSLARILREKGAVGEIVGIGRGEANLRKAVELGVIDRYSLDSVAGVEGADVVFLATPVCSIPSIT
AEIAPHLAPGCVVTDGGSVKEEIVSACEPLMPNGIHFVGGHPIAGTEHSGVEASFSSLYVGKRCIVTPTSRTSQDALAKV
VRMWEVAGSEVVIMDTEKHDRVLAAISHLPHMVAYALVNAVEGYDRFEESILRYSAGGFRDFTRIASSDPAMWRDIALMN
REAVIEMMDHFAAYFARLRELVAAADAPGLERFFRESKESRDAIL

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 30775; Mature: 30644

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFIHRLAIIGVGLIGGSLARILREKGAVGEIVGIGRGEANLRKAVELGVIDRYSLDSVA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHC
GVEGADVVFLATPVCSIPSITAEIAPHLAPGCVVTDGGSVKEEIVSACEPLMPNGIHFVG
CCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEC
GHPIAGTEHSGVEASFSSLYVGKRCIVTPTSRTSQDALAKVVRMWEVAGSEVVIMDTEKH
CCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHH
DRVLAAISHLPHMVAYALVNAVEGYDRFEESILRYSAGGFRDFTRIASSDPAMWRDIALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHH
NREAVIEMMDHFAAYFARLRELVAAADAPGLERFFRESKESRDAIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFIHRLAIIGVGLIGGSLARILREKGAVGEIVGIGRGEANLRKAVELGVIDRYSLDSVA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHC
GVEGADVVFLATPVCSIPSITAEIAPHLAPGCVVTDGGSVKEEIVSACEPLMPNGIHFVG
CCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEC
GHPIAGTEHSGVEASFSSLYVGKRCIVTPTSRTSQDALAKVVRMWEVAGSEVVIMDTEKH
CCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHH
DRVLAAISHLPHMVAYALVNAVEGYDRFEESILRYSAGGFRDFTRIASSDPAMWRDIALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHH
NREAVIEMMDHFAAYFARLRELVAAADAPGLERFFRESKESRDAIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]