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The map label for this gene is aroA

Identifier: 78222084

GI number: 78222084

Start: 953523

End: 954812

Strand: Direct

Name: aroA

Synonym: Gmet_0864

Alternate gene names: 78222084

Gene position: 953523-954812 (Clockwise)

Preceding gene: 78222083

Following gene: 78222085

Centisome position: 23.85

GC content: 64.42

Gene sequence:

>1290_bases
GTGCAGAGCTATACCGTTCGGCCGGCCAAGGGGATTCGTGGCGAGATCACCGTTCCCGGCGACAAGTCCATATCCCACCG
TTCCATCATGCTCGGTTCCATTGCCCGCGGGGAAACCACGGTGCGCGGCTTTCTCCGGGGCGAGGACAATATTGCCACCC
TGAACGCCTTCCGGGCCATGGGCGTTGTCATCGACGACGACGGCGAGACGCTCCGCATCGCCGGGAAAGGACTTCGTGGC
CTCGCGGAACCGACGGACGTCCTTGACTGCGGCAATTCCGGGACTTCCATGAGGCTTCTGACCGGTCTTCTGGCTCCCCA
ACGGTTCTACTCGGTGCTGTCCGGCGACCAGTACCTGCGGCGCCGTCCCATGCGGCGGGTGGTGGAGCCCCTCTCACGGA
TGGGTGCCTGCATTCATGGTCGTGAAGGAGGGGAAAAGGCGCCCCTTGCCATTGTCGGACGGGACCTGAAAGGGATCTCC
TACACGTCGTCCGTTGCGAGTGCCCAGGTGAAGTCGGCGCTCATGCTGGCCGGGCTCTATGCAGAAGGTGAGACGCGGGT
TACCGAGCCGCACCTTTCCCGGGATCACTCGGAGCGGATGTTTCGCCACTTCGGAGCCGACATCGAGAACGGCCCCGCCG
GAGTAGTCGTCCGCGGCGGCCGGGAGTTGGAAGGGCGGGACATTATAGTTCCCGGAGATATCTCGTCTGCCGCCTTCTTC
ATGGTGGCGGCCCTCATCGTCCCCGGCTCCGAGCTTCTCATCCGCGGGGTCGGGGTGAACCCGACACGCACCGGCATCAT
CGACATCCTGACCGCCATGGGAGGCTCCCTGGAGTTGCTCGACCAGCGGGAGGTTTCCGGAGAGCCGGTTGCCGATATAC
TGGTACGCTCGTCTCGCCTCAAGGGGATTGAAATTGCCGGCGAGGTGGTCCCCCGGGCCATCGATGAATTCCCCGTCATC
TGTGTCGCCGCTGCCGTGGCCGAGGGGCGCACTGTCGTCAGGGAGGCCCGGGAACTCCGTGTCAAGGAGACCGACCGGAT
TGCCGCCATGGCCACCAACCTGCGGGCGGTAGGTGTGACGGTCACCGAAAGCGAAGACGGCATGGATATCGAGGGGGCGG
AGCAGATTGCCGCAGGCACCGTGGAGAGCTTCGGCGATCACCGGATCGCCATGTCGATGCTCATCGCGGGCCTCACGGCA
GGGGGCGATATTACCGTTACCGACACCGAGTGTATCGGCACGTCGTTCCCCACGTTCTTCCCGCTGCTCGAAAAGGTTGC
GGCCCGGTGA

Upstream 100 bases:

>100_bases
ACGCCCCTGGACTCGAACGCTTCTTCCGGGAATCGAAGGAAAGCAGAGACGCTATTCTGTAGGGAAGGCAGTTCCTAAAT
CTCAGCCAAGGTGGTTAATC

Downstream 100 bases:

>100_bases
GCGGCGTGGGAAGACGGGGACTCATCATAGCCATTGACGGACCCTCCGGCGCAGGGAAGAGCACCATCACCAAGCGCCTG
GCCGACCGCCTCGGCTATGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQSYTVRPAKGIRGEITVPGDKSISHRSIMLGSIARGETTVRGFLRGEDNIATLNAFRAMGVVIDDDGETLRIAGKGLRG
LAEPTDVLDCGNSGTSMRLLTGLLAPQRFYSVLSGDQYLRRRPMRRVVEPLSRMGACIHGREGGEKAPLAIVGRDLKGIS
YTSSVASAQVKSALMLAGLYAEGETRVTEPHLSRDHSERMFRHFGADIENGPAGVVVRGGRELEGRDIIVPGDISSAAFF
MVAALIVPGSELLIRGVGVNPTRTGIIDILTAMGGSLELLDQREVSGEPVADILVRSSRLKGIEIAGEVVPRAIDEFPVI
CVAAAVAEGRTVVREARELRVKETDRIAAMATNLRAVGVTVTESEDGMDIEGAEQIAAGTVESFGDHRIAMSMLIAGLTA
GGDITVTDTECIGTSFPTFFPLLEKVAAR

Sequences:

>Translated_429_residues
MQSYTVRPAKGIRGEITVPGDKSISHRSIMLGSIARGETTVRGFLRGEDNIATLNAFRAMGVVIDDDGETLRIAGKGLRG
LAEPTDVLDCGNSGTSMRLLTGLLAPQRFYSVLSGDQYLRRRPMRRVVEPLSRMGACIHGREGGEKAPLAIVGRDLKGIS
YTSSVASAQVKSALMLAGLYAEGETRVTEPHLSRDHSERMFRHFGADIENGPAGVVVRGGRELEGRDIIVPGDISSAAFF
MVAALIVPGSELLIRGVGVNPTRTGIIDILTAMGGSLELLDQREVSGEPVADILVRSSRLKGIEIAGEVVPRAIDEFPVI
CVAAAVAEGRTVVREARELRVKETDRIAAMATNLRAVGVTVTESEDGMDIEGAEQIAAGTVESFGDHRIAMSMLIAGLTA
GGDITVTDTECIGTSFPTFFPLLEKVAAR
>Mature_429_residues
MQSYTVRPAKGIRGEITVPGDKSISHRSIMLGSIARGETTVRGFLRGEDNIATLNAFRAMGVVIDDDGETLRIAGKGLRG
LAEPTDVLDCGNSGTSMRLLTGLLAPQRFYSVLSGDQYLRRRPMRRVVEPLSRMGACIHGREGGEKAPLAIVGRDLKGIS
YTSSVASAQVKSALMLAGLYAEGETRVTEPHLSRDHSERMFRHFGADIENGPAGVVVRGGRELEGRDIIVPGDISSAAFF
MVAALIVPGSELLIRGVGVNPTRTGIIDILTAMGGSLELLDQREVSGEPVADILVRSSRLKGIEIAGEVVPRAIDEFPVI
CVAAAVAEGRTVVREARELRVKETDRIAAMATNLRAVGVTVTESEDGMDIEGAEQIAAGTVESFGDHRIAMSMLIAGLTA
GGDITVTDTECIGTSFPTFFPLLEKVAAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=440, Percent_Identity=31.1363636363636, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6320332, Length=455, Percent_Identity=27.4725274725275, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_GEOMG (Q39XB8)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383831.1
- HSSP:   P22487
- ProteinModelPortal:   Q39XB8
- SMR:   Q39XB8
- STRING:   Q39XB8
- GeneID:   3739293
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0864
- NMPDR:   fig|269799.3.peg.939
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   PAPSRDH
- PhylomeDB:   Q39XB8
- ProtClustDB:   PRK02427
- BioCyc:   GMET269799:GMET_0864-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45625; Mature: 45625

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYTVRPAKGIRGEITVPGDKSISHRSIMLGSIARGETTVRGFLRGEDNIATLNAFRAM
CCCCCCCCCCCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHEECCCCCEEHHHHHHHE
GVVIDDDGETLRIAGKGLRGLAEPTDVLDCGNSGTSMRLLTGLLAPQRFYSVLSGDQYLR
EEEECCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCHHHHH
RRPMRRVVEPLSRMGACIHGREGGEKAPLAIVGRDLKGISYTSSVASAQVKSALMLAGLY
HHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
AEGETRVTEPHLSRDHSERMFRHFGADIENGPAGVVVRGGRELEGRDIIVPGDISSAAFF
CCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHH
MVAALIVPGSELLIRGVGVNPTRTGIIDILTAMGGSLELLDQREVSGEPVADILVRSSRL
HHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHCCCCEEEHHCCCCCCCCHHHHHHHHHCC
KGIEIAGEVVPRAIDEFPVICVAAAVAEGRTVVREARELRVKETDRIAAMATNLRAVGVT
CCEEHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEE
VTESEDGMDIEGAEQIAAGTVESFGDHRIAMSMLIAGLTAGGDITVTDTECIGTSFPTFF
EECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHCCCCCHHHH
PLLEKVAAR
HHHHHHHCC
>Mature Secondary Structure
MQSYTVRPAKGIRGEITVPGDKSISHRSIMLGSIARGETTVRGFLRGEDNIATLNAFRAM
CCCCCCCCCCCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHEECCCCCEEHHHHHHHE
GVVIDDDGETLRIAGKGLRGLAEPTDVLDCGNSGTSMRLLTGLLAPQRFYSVLSGDQYLR
EEEECCCCCEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCHHHHH
RRPMRRVVEPLSRMGACIHGREGGEKAPLAIVGRDLKGISYTSSVASAQVKSALMLAGLY
HHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
AEGETRVTEPHLSRDHSERMFRHFGADIENGPAGVVVRGGRELEGRDIIVPGDISSAAFF
CCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHH
MVAALIVPGSELLIRGVGVNPTRTGIIDILTAMGGSLELLDQREVSGEPVADILVRSSRL
HHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHCCCCEEEHHCCCCCCCCHHHHHHHHHCC
KGIEIAGEVVPRAIDEFPVICVAAAVAEGRTVVREARELRVKETDRIAAMATNLRAVGVT
CCEEHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEE
VTESEDGMDIEGAEQIAAGTVESFGDHRIAMSMLIAGLTAGGDITVTDTECIGTSFPTFF
EECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHCCCCCHHHH
PLLEKVAAR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA