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The map label for this gene is pagR [H]

Identifier: 78222066

GI number: 78222066

Start: 931626

End: 931901

Strand: Reverse

Name: pagR [H]

Synonym: Gmet_0846

Alternate gene names: 78222066

Gene position: 931901-931626 (Counterclockwise)

Preceding gene: 78222067

Following gene: 78222065

Centisome position: 23.31

GC content: 57.97

Gene sequence:

>276_bases
ATGGACTTCGACATCAGCAGGAATTTCTCCGAGGAAGCGGAAATCTTCAAGGTGCTCGGCCACCCGATCCGGCTCAAGAT
CGTTGCAGGGCTCTGTACGCGGGAGTGCAACGTGAAGCATATCTGGGAGTGCCTCGGACTTCCCCAGGCCACCGTCTCCC
AGCATCTGGCCCTTCTGAAGAACAAGGGAATCATCGAGGGGAAGCGGGACGGGGTGGAAGTCCACTACTCGGTGGTACAT
CCCCTGGCCAAGAAACTCATCGAGGTTCTCGGCTGA

Upstream 100 bases:

>100_bases
AGGTCGGGAACAATATAAATATATTTAGATTTCTCCTCAAACGTGAGGGGAGTTGCACTCTGCATGGCAAGGGTTCTCCC
CCGGCCACAGGACGGAATCC

Downstream 100 bases:

>100_bases
ACGGCAGCCTGCATACCGACACCACACGAATCCCCTCCCGGCGAGGGGATTTTTTTTGGAGATGACCATGGAAACGACCA
CTATCCGCGTGACCCTCAAC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MDFDISRNFSEEAEIFKVLGHPIRLKIVAGLCTRECNVKHIWECLGLPQATVSQHLALLKNKGIIEGKRDGVEVHYSVVH
PLAKKLIEVLG

Sequences:

>Translated_91_residues
MDFDISRNFSEEAEIFKVLGHPIRLKIVAGLCTRECNVKHIWECLGLPQATVSQHLALLKNKGIIEGKRDGVEVHYSVVH
PLAKKLIEVLG
>Mature_91_residues
MDFDISRNFSEEAEIFKVLGHPIRLKIVAGLCTRECNVKHIWECLGLPQATVSQHLALLKNKGIIEGKRDGVEVHYSVVH
PLAKKLIEVLG

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10201; Mature: 10201

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDISRNFSEEAEIFKVLGHPIRLKIVAGLCTRECNVKHIWECLGLPQATVSQHLALLK
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NKGIIEGKRDGVEVHYSVVHPLAKKLIEVLG
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDFDISRNFSEEAEIFKVLGHPIRLKIVAGLCTRECNVKHIWECLGLPQATVSQHLALLK
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NKGIIEGKRDGVEVHYSVVHPLAKKLIEVLG
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]