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The map label for this gene is iorA [H]

Identifier: 78222058

GI number: 78222058

Start: 924109

End: 924573

Strand: Reverse

Name: iorA [H]

Synonym: Gmet_0838

Alternate gene names: 78222058

Gene position: 924573-924109 (Counterclockwise)

Preceding gene: 78222059

Following gene: 78222057

Centisome position: 23.13

GC content: 66.88

Gene sequence:

>465_bases
ATGATAGCTCTGACTGTCAACGGCACGCGGCACCAGGTGGACGTTCCCCCCGACACGCCGCTTCTCTGGGTGATCCGGGA
GGTGATCGGCCTCACGGGAACCAAATTCGGCTGCGGCATGTCCCTCTGCGGCGCCTGTACCGTCCACGTGGAGGGGCGGG
CGATCCGCTCCTGCGTCACCCCCGTGTCGGCCGTGGCCGGCAAGGAGGTAACCACCATCGAGGGGATTCCCGAGTCTCAC
CCGGTGAAGCAGGCGTGGATCGCCGATGATGTCCCCCAATGCGGCTGGTGCCAGCCGGGACAGATTATGGCTGCCACGGC
CCTTCTGGCAACTAACCCCAAGCCCGACGATGCCGCCATTGACGAGGCCATGGAGGGAATCCTCTGCCGATGCGGCACCT
ACCAGCGCATCCGCCGGGCAATCCACCGGGCCGCCGGCACGCCGGCGAAAGGGGGTGCGTCATGA

Upstream 100 bases:

>100_bases
GGTAATCTCCACGGTCAAGAGCGCCACGGCAAAGGATAGCCGCGAAACCAGCTTTACGGTGCGGTAGCCGCACCCCCATC
CACGGAAGGAGGGAAAACGC

Downstream 100 bases:

>100_bases
GCGGAATCGTCATCGTGAGCCGCCGTGATTTTCTGAAGGCAGGCATCGTTCTGGGGGGCGGGCTGATCATAGGGGTCCAC
CTGCCGGGAGGAACCGCCGC

Product: ferredoxin:(2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIALTVNGTRHQVDVPPDTPLLWVIREVIGLTGTKFGCGMSLCGACTVHVEGRAIRSCVTPVSAVAGKEVTTIEGIPESH
PVKQAWIADDVPQCGWCQPGQIMAATALLATNPKPDDAAIDEAMEGILCRCGTYQRIRRAIHRAAGTPAKGGAS

Sequences:

>Translated_154_residues
MIALTVNGTRHQVDVPPDTPLLWVIREVIGLTGTKFGCGMSLCGACTVHVEGRAIRSCVTPVSAVAGKEVTTIEGIPESH
PVKQAWIADDVPQCGWCQPGQIMAATALLATNPKPDDAAIDEAMEGILCRCGTYQRIRRAIHRAAGTPAKGGAS
>Mature_154_residues
MIALTVNGTRHQVDVPPDTPLLWVIREVIGLTGTKFGCGMSLCGACTVHVEGRAIRSCVTPVSAVAGKEVTTIEGIPESH
PVKQAWIADDVPQCGWCQPGQIMAATALLATNPKPDDAAIDEAMEGILCRCGTYQRIRRAIHRAAGTPAKGGAS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=36.0544217687075, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI71773480, Length=85, Percent_Identity=36.4705882352941, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=40.4907975460123, Blast_Score=109, Evalue=9e-26,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=40.5063291139241, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=34.6153846153846, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=34.6153846153846, Blast_Score=92, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=36.8421052631579, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=35, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=32.7160493827161, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=32.7160493827161, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=33.1168831168831, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16172; Mature: 16172

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALTVNGTRHQVDVPPDTPLLWVIREVIGLTGTKFGCGMSLCGACTVHVEGRAIRSCVT
CEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEECCHHHHHHHH
PVSAVAGKEVTTIEGIPESHPVKQAWIADDVPQCGWCQPGQIMAATALLATNPKPDDAAI
HHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
DEAMEGILCRCGTYQRIRRAIHRAAGTPAKGGAS
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIALTVNGTRHQVDVPPDTPLLWVIREVIGLTGTKFGCGMSLCGACTVHVEGRAIRSCVT
CEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEECCHHHHHHHH
PVSAVAGKEVTTIEGIPESHPVKQAWIADDVPQCGWCQPGQIMAATALLATNPKPDDAAI
HHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
DEAMEGILCRCGTYQRIRRAIHRAAGTPAKGGAS
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]