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The map label for this gene is crp [C]

Identifier: 78221970

GI number: 78221970

Start: 824509

End: 825225

Strand: Reverse

Name: crp [C]

Synonym: Gmet_0750

Alternate gene names: 78221970

Gene position: 825225-824509 (Counterclockwise)

Preceding gene: 78221971

Following gene: 78221969

Centisome position: 20.64

GC content: 56.21

Gene sequence:

>717_bases
ATGAACTCCAAGAATCCACGTACAACCATACCGGCCCCTCTCCAATCGATTCTGAGCGCCATTCCGCTCTTTGCCCCCCT
CCCACCCGATGACATCAATACGTTAAGCAAGCTCATTGAGATCCAGGTCTTTCCGAAAAATCGCACCATCCTTCATGAAG
CCGATACAGCCAACTACATGTACCTCGTCCTTGCGGGAAAAGTGCGGGTAGTCCAGCACAGCAACGACGGCACGGAACAG
GTCCTTGCCATTCATCGCAAGGGGGCGTTTTTCGGCGAAATGGCCCTCCTTGACGGCCGCACGTCTCCGGCAACGCTCAT
CGCCCACGAAGACGCCACCGTCGGCCTCATTGCCCGGACAGCCTTTGAAAACCAGATTCTCACCAACGACCGGATGCTGC
GGCAGATCATCAGCGTGCTTTGTTCGCGGCTGCGCGAATCATGGTTCCTCATGAAGCTGTCACGCTTTTCCTCCGCCGAG
CAGAAGGTCAGGGGAGTCCTCAAATATCTCGGAACCCAGTATGGCGTGGACGATTCTCGTGGCAAAATTCTCAGCATCAA
GCTAACCCACCGCACCGTCGCCGGTTACGCATCGGTATCCCGGGAGACGGCAAGCCGCATTTTGGGCCGCTTCTCCCGTG
CTGGAGAGATCGAACTCCTCGCCAGCAGAAGAATGCTCCTCAAACCTACCCTCTTTCTCAATCCCCCGTTTTTGTGA

Upstream 100 bases:

>100_bases
AGCCCCTCCCCTCTTTTTTTGTCTGTTACCCTGTTACGTGTATTCATCTTCAAGGCTGCTATACTTGCATTATAATCCGG
CAACCGACAGGTATCTCACC

Downstream 100 bases:

>100_bases
TTCAAGTCACATTTTTTCCCCTCAAGTTATCCATCCTGACGCCGAAATGTAGTAACAGATAAAGAAGAAAGTTTCCGAAA
GGGCAAACTTCGGGTAACCG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Catabolite Gene Activator; CRP Family Transcriptional Regulator; Transcriptional Regulatory Protein; Cyclic AMP Receptor Protein; Pyruvate Formate-Lyase 1-Activating; Crp-Family Transcriptional Regulator; Transcription Regulator; CAMP-Bindin Transcriptional Regulator; Transcription Regulator Crp Family; Pyruvate-Formate-Lyase-Activating; Global Nitrogen Regulator NtcA; Response Regulator Receiver; Transcriptional Regulatory Protein Crp Family; CAMP-Dependent Transcriptional Regulator; Crp Family Regulatory Protein

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNSKNPRTTIPAPLQSILSAIPLFAPLPPDDINTLSKLIEIQVFPKNRTILHEADTANYMYLVLAGKVRVVQHSNDGTEQ
VLAIHRKGAFFGEMALLDGRTSPATLIAHEDATVGLIARTAFENQILTNDRMLRQIISVLCSRLRESWFLMKLSRFSSAE
QKVRGVLKYLGTQYGVDDSRGKILSIKLTHRTVAGYASVSRETASRILGRFSRAGEIELLASRRMLLKPTLFLNPPFL

Sequences:

>Translated_238_residues
MNSKNPRTTIPAPLQSILSAIPLFAPLPPDDINTLSKLIEIQVFPKNRTILHEADTANYMYLVLAGKVRVVQHSNDGTEQ
VLAIHRKGAFFGEMALLDGRTSPATLIAHEDATVGLIARTAFENQILTNDRMLRQIISVLCSRLRESWFLMKLSRFSSAE
QKVRGVLKYLGTQYGVDDSRGKILSIKLTHRTVAGYASVSRETASRILGRFSRAGEIELLASRRMLLKPTLFLNPPFL
>Mature_238_residues
MNSKNPRTTIPAPLQSILSAIPLFAPLPPDDINTLSKLIEIQVFPKNRTILHEADTANYMYLVLAGKVRVVQHSNDGTEQ
VLAIHRKGAFFGEMALLDGRTSPATLIAHEDATVGLIARTAFENQILTNDRMLRQIISVLCSRLRESWFLMKLSRFSSAE
QKVRGVLKYLGTQYGVDDSRGKILSIKLTHRTVAGYASVSRETASRILGRFSRAGEIELLASRRMLLKPTLFLNPPFL

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26544; Mature: 26544

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2 ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKNPRTTIPAPLQSILSAIPLFAPLPPDDINTLSKLIEIQVFPKNRTILHEADTANYM
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCEEEEECCCCCEE
YLVLAGKVRVVQHSNDGTEQVLAIHRKGAFFGEMALLDGRTSPATLIAHEDATVGLIART
EEEEECEEEEEEECCCCHHHHHHHHHCCCCHHHHHEECCCCCCEEEEEECCCCEEHHHHH
AFENQILTNDRMLRQIISVLCSRLRESWFLMKLSRFSSAEQKVRGVLKYLGTQYGVDDSR
HHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
GKILSIKLTHRTVAGYASVSRETASRILGRFSRAGEIELLASRRMLLKPTLFLNPPFL
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHCCCHHHHCCEEECCCCCC
>Mature Secondary Structure
MNSKNPRTTIPAPLQSILSAIPLFAPLPPDDINTLSKLIEIQVFPKNRTILHEADTANYM
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEECCCCEEEEECCCCCEE
YLVLAGKVRVVQHSNDGTEQVLAIHRKGAFFGEMALLDGRTSPATLIAHEDATVGLIART
EEEEECEEEEEEECCCCHHHHHHHHHCCCCHHHHHEECCCCCCEEEEEECCCCEEHHHHH
AFENQILTNDRMLRQIISVLCSRLRESWFLMKLSRFSSAEQKVRGVLKYLGTQYGVDDSR
HHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
GKILSIKLTHRTVAGYASVSRETASRILGRFSRAGEIELLASRRMLLKPTLFLNPPFL
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHCCCHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA