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The map label for this gene is ruvA

Identifier: 78221965

GI number: 78221965

Start: 818987

End: 819586

Strand: Direct

Name: ruvA

Synonym: Gmet_0745

Alternate gene names: 78221965

Gene position: 818987-819586 (Clockwise)

Preceding gene: 78221964

Following gene: 78221966

Centisome position: 20.49

GC content: 61.5

Gene sequence:

>600_bases
ATGATAGCCCGTCTCACCGGCATGCTCGCCCACAAGTCCCCCGACGCCATCATCATCGACGTGAACGGTGTCGGCTACCG
GGTCCAGATCCCCTTTTCCACCTACTACGAGCTTCCCGATGAGGGGAAGACGGTTTCCCTTTCCATTTACACCCACGTCA
AGGAAGACGCCATCAGCCTCTTCGGGTTCAGGACCGTTGCCGAGAAGGAGTTCTTCCAGGTTCTCATCTCCGTTTCCGGC
ATCGGCCCCAAGATGGCCCGGGACATCCTCTCCAACATCCAGCCCGACGAGCTGGCCGGAGCCATCCTCCAGGGGAATCT
GGTCCGGCTCTCGTCGATTCCCGGCATCGGGAAGAAGACCGCCGAACGCCTCGTGCTGGAGCTGAAGGAGAAGGTGCGGA
AGATGGATGTAGCTCCCTCGACAAAGGAGGCGGCCCCCAGCGAGGCACCCCCCGAAGTGGCCGATGACGTGGCCTCCGCC
CTGGTGAACCTGGGCTACAAGGAGGCGGTGGTCCGTAAGGTGCTGGCGGAAATGGCCATCGAATCCGGCGCCTCCACCGA
AGCGGTCCTCCGGCAGGCATTGAAGATTCTGATGAAATGA

Upstream 100 bases:

>100_bases
ACCTTCCTGAGATCGCCCAGGCCGACGCCTCCGACGCATTGGCCGTGGCGGTCTGTCACGCCAATTCGGCCGGCATGAAA
AACATCCTCCGGAGCATCAG

Downstream 100 bases:

>100_bases
CAATGTAGGGGCAATTCATGAATTGCCCTTACGGGTAGACACCCGTTATGACCCGACTCGTTACCCCCGACATAACCGAA
GACGACCTGATCGAATCGTC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISLFGFRTVAEKEFFQVLISVSG
IGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASA
LVNLGYKEAVVRKVLAEMAIESGASTEAVLRQALKILMK

Sequences:

>Translated_199_residues
MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISLFGFRTVAEKEFFQVLISVSG
IGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASA
LVNLGYKEAVVRKVLAEMAIESGASTEAVLRQALKILMK
>Mature_199_residues
MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISLFGFRTVAEKEFFQVLISVSG
IGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASA
LVNLGYKEAVVRKVLAEMAIESGASTEAVLRQALKILMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=36.318407960199, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_GEOMG (Q39XN7)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383712.1
- HSSP:   P40832
- ProteinModelPortal:   Q39XN7
- SMR:   Q39XN7
- STRING:   Q39XN7
- GeneID:   3740551
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0745
- NMPDR:   fig|269799.3.peg.772
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q39XN7
- ProtClustDB:   PRK00116
- BioCyc:   GMET269799:GMET_0745-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21507; Mature: 21507

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISL
CCHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHCCCCCCCCEEEEEEEEHHHHHHHHH
FGFRTVAEKEFFQVLISVSGIGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCHHH
AERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASALVNLGYKEAVVRKVLAEMAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ESGASTEAVLRQALKILMK
HCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISL
CCHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHCCCCCCCCEEEEEEEEHHHHHHHHH
FGFRTVAEKEFFQVLISVSGIGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCHHH
AERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASALVNLGYKEAVVRKVLAEMAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ESGASTEAVLRQALKILMK
HCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA