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The map label for this gene is yhdR [H]

Identifier: 78221952

GI number: 78221952

Start: 805086

End: 806279

Strand: Reverse

Name: yhdR [H]

Synonym: Gmet_0732

Alternate gene names: 78221952

Gene position: 806279-805086 (Counterclockwise)

Preceding gene: 78221958

Following gene: 78221948

Centisome position: 20.17

GC content: 64.57

Gene sequence:

>1194_bases
ATGCCCATCGCCACAAAAATCGCCGGCCACATCTCCAAGTCGTCCTGGATCAGGAAGATGTTCGAGGAGGGGGAGCGGCT
GCGCCAGGTCCACGGGGCCGAGAACGTGTACGACTTCACCCTCGGCAATCCCGACACGGAGCCCCCCCGGGAGTTCCAGG
AGGAGTTCGCCCGCCTCGCCACCAATCCCATCCCCGGCATGCACCGCTACATGAACAACGCCGGCTACCAGGAGACCCGG
GCCGCCGTGGCTGAGGTGCTTGCCGAGGCGTCCGGCCTCCCCGTGGAAGCCGGGCACGTGGTGATGACCTGCGGGGCCGG
CGGCGCCCTGAACGTGGTCCTAAAGACCATCCTCAATCCGGGCGAAGAGGTGATCATCCTCACCCCCTACTTCGTGGAGT
ACAAGTTCTACATCGACAACCACGGCGGGGTGCCGAAGGAGGTCTGGACCAACAGGGAGACCTTCCAGCTGAACATCCCG
GCCATCGAAGCCGCCATCACCAACAAAACCCGGGCCGTCATCATCTGCTCCCCCAACAACCCCACCGGCGTCATCTACCC
GGAAGAGAGCCTGAAGGAACTGGGCGAAATGCTTGCGCGGGCAGAGCGGCGCTACGACCGACAGATTTACGTCATCTCCG
ACGAACCCTACGCCCGGATCGCCTTTGACGGCAAGCATGTGCCGAACATCTTCCGGTACGTGGAGAGCTCGGTCATCGTC
ACCTCCCACAGCAAGGACCTGGCACTCCCCGGCGAGCGGATCGGCTACCTGGCCGTCAACCCCAGTGCCCGGGGAGTAGA
GCAGTTCGTGGAAGGGGCGGTCTTCAGCAACCGGGTCCTCGGCTACGTGAACGCGCCGGCCCTCATGCAGCGGCTCGTGA
CAAAGCTCCAGCGGGCCTCCGTGGACATCGGCGAGTACCAGTCCAAGCGGGACCTTCTCTACGACCGCCTCACCGCCATG
GGCTTCGAGATGGTGCGGCCCGACGGCGCCTTTTACCTCTTTCCCAAGTCACCGCTGACCGACGATGTGGAGTTCGTGAA
GATGGCCCAGAAACACCGGATTCTGCTGGTTCCCGGGGCCGGCTTCGGCGCCCCCGGCTTCTTCCGGATTGCCTACTGCG
TCGACCGGGGAATGATCGAGCGGAGTCTTCCCGCCTGGCAACAGCTGGCCCGGGAGACGGGGCTGGGGGGATAG

Upstream 100 bases:

>100_bases
AGATTGGCACGATTCCAAGCTTAAAACAACTGCATTCTTGCCCATTGATCTAGTCCTGTGCTACAAATTCGCATATCCAT
TTTACAGCGAGGTTGTCACC

Downstream 100 bases:

>100_bases
CGTTGGAGGGAAACTCCACGAAAAAGAGCGGTGCCTGAAGGGGCATCGCTCTTTTCGCTTCCGGCATGACCGGGGCGTCA
CGCCGGGGGGAGCGTGAACG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPIATKIAGHISKSSWIRKMFEEGERLRQVHGAENVYDFTLGNPDTEPPREFQEEFARLATNPIPGMHRYMNNAGYQETR
AAVAEVLAEASGLPVEAGHVVMTCGAGGALNVVLKTILNPGEEVIILTPYFVEYKFYIDNHGGVPKEVWTNRETFQLNIP
AIEAAITNKTRAVIICSPNNPTGVIYPEESLKELGEMLARAERRYDRQIYVISDEPYARIAFDGKHVPNIFRYVESSVIV
TSHSKDLALPGERIGYLAVNPSARGVEQFVEGAVFSNRVLGYVNAPALMQRLVTKLQRASVDIGEYQSKRDLLYDRLTAM
GFEMVRPDGAFYLFPKSPLTDDVEFVKMAQKHRILLVPGAGFGAPGFFRIAYCVDRGMIERSLPAWQQLARETGLGG

Sequences:

>Translated_397_residues
MPIATKIAGHISKSSWIRKMFEEGERLRQVHGAENVYDFTLGNPDTEPPREFQEEFARLATNPIPGMHRYMNNAGYQETR
AAVAEVLAEASGLPVEAGHVVMTCGAGGALNVVLKTILNPGEEVIILTPYFVEYKFYIDNHGGVPKEVWTNRETFQLNIP
AIEAAITNKTRAVIICSPNNPTGVIYPEESLKELGEMLARAERRYDRQIYVISDEPYARIAFDGKHVPNIFRYVESSVIV
TSHSKDLALPGERIGYLAVNPSARGVEQFVEGAVFSNRVLGYVNAPALMQRLVTKLQRASVDIGEYQSKRDLLYDRLTAM
GFEMVRPDGAFYLFPKSPLTDDVEFVKMAQKHRILLVPGAGFGAPGFFRIAYCVDRGMIERSLPAWQQLARETGLGG
>Mature_396_residues
PIATKIAGHISKSSWIRKMFEEGERLRQVHGAENVYDFTLGNPDTEPPREFQEEFARLATNPIPGMHRYMNNAGYQETRA
AVAEVLAEASGLPVEAGHVVMTCGAGGALNVVLKTILNPGEEVIILTPYFVEYKFYIDNHGGVPKEVWTNRETFQLNIPA
IEAAITNKTRAVIICSPNNPTGVIYPEESLKELGEMLARAERRYDRQIYVISDEPYARIAFDGKHVPNIFRYVESSVIVT
SHSKDLALPGERIGYLAVNPSARGVEQFVEGAVFSNRVLGYVNAPALMQRLVTKLQRASVDIGEYQSKRDLLYDRLTAMG
FEMVRPDGAFYLFPKSPLTDDVEFVKMAQKHRILLVPGAGFGAPGFFRIAYCVDRGMIERSLPAWQQLARETGLGG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=373, Percent_Identity=23.0563002680965, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI56713256, Length=372, Percent_Identity=23.1182795698925, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4507369, Length=355, Percent_Identity=25.6338028169014, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI95147551, Length=347, Percent_Identity=22.7665706051873, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169881279, Length=347, Percent_Identity=22.7665706051873, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=27.6712328767123, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=24.21875, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=24.468085106383, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=322, Percent_Identity=23.2919254658385, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=21.978021978022, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=21.978021978022, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=369, Percent_Identity=24.390243902439, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=356, Percent_Identity=24.438202247191, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI18859735, Length=338, Percent_Identity=26.3313609467456, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=22.6470588235294, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=22.6470588235294, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=22.6470588235294, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=22.6470588235294, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44231; Mature: 44100

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIATKIAGHISKSSWIRKMFEEGERLRQVHGAENVYDFTLGNPDTEPPREFQEEFARLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
TNPIPGMHRYMNNAGYQETRAAVAEVLAEASGLPVEAGHVVMTCGAGGALNVVLKTILNP
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHCC
GEEVIILTPYFVEYKFYIDNHGGVPKEVWTNRETFQLNIPAIEAAITNKTRAVIICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCHHHHCCCCEEEEECCCEEHEECCCCEEEEEECCCC
PTGVIYPEESLKELGEMLARAERRYDRQIYVISDEPYARIAFDGKHVPNIFRYVESSVIV
CCEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCEEE
TSHSKDLALPGERIGYLAVNPSARGVEQFVEGAVFSNRVLGYVNAPALMQRLVTKLQRAS
EECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHC
VDIGEYQSKRDLLYDRLTAMGFEMVRPDGAFYLFPKSPLTDDVEFVKMAQKHRILLVPGA
CCHHHHHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCCHHHHHHHHHHCEEEEEECC
GFGAPGFFRIAYCVDRGMIERSLPAWQQLARETGLGG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIATKIAGHISKSSWIRKMFEEGERLRQVHGAENVYDFTLGNPDTEPPREFQEEFARLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
TNPIPGMHRYMNNAGYQETRAAVAEVLAEASGLPVEAGHVVMTCGAGGALNVVLKTILNP
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHCC
GEEVIILTPYFVEYKFYIDNHGGVPKEVWTNRETFQLNIPAIEAAITNKTRAVIICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCHHHHCCCCEEEEECCCEEHEECCCCEEEEEECCCC
PTGVIYPEESLKELGEMLARAERRYDRQIYVISDEPYARIAFDGKHVPNIFRYVESSVIV
CCEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCEEE
TSHSKDLALPGERIGYLAVNPSARGVEQFVEGAVFSNRVLGYVNAPALMQRLVTKLQRAS
EECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHC
VDIGEYQSKRDLLYDRLTAMGFEMVRPDGAFYLFPKSPLTDDVEFVKMAQKHRILLVPGA
CCHHHHHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCCHHHHHHHHHHCEEEEEECC
GFGAPGFFRIAYCVDRGMIERSLPAWQQLARETGLGG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]