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The map label for this gene is argC

Identifier: 78221829

GI number: 78221829

Start: 678076

End: 679116

Strand: Direct

Name: argC

Synonym: Gmet_0608

Alternate gene names: 78221829

Gene position: 678076-679116 (Clockwise)

Preceding gene: 78221828

Following gene: 78221830

Centisome position: 16.96

GC content: 59.75

Gene sequence:

>1041_bases
ATGCTGAATGTTGCCGTCGTCGGAGCGAGCGGATACACCGGAGTCGAGCTGCTCAGGCTGCTTTACTGCCATCCCGAGGT
GGCTGTCACCTGTATTACCTCTGAACAGAGCGCCGGCCGGCCCGTCGCCGCTGTCTTCCCGACGTTGCGCAGCCGCTACA
CACAGGTGCTTGAGAATCTGGAACCGGTCAAGGTGGCCCAGAAGGCCGACCTTATCTTTACGGCCCTTCCCCACAAGGCG
GCTATGGAAGTGGTTCCCACGTTTCTGGAGCTGGGGAAGAGGGTGGTTGACCTCTCCGCCGACTATCGCTTCAATGATCC
AGCCGTTTATGAGAAGTGGTACGAACCCCACATGAACCCCGAGAACCTGAAGGAGGCGGTCTACGGCCTTCCAGAGATCC
GGCGGGAGAAGATCGGTGATGCCTGGCTCGTGGGTAACCCCGGCTGCTACCCCACGAGCGTCATTCTGGGGCTCATGCCG
CTCCTGAAAAAGCGCCTTATCGACCCGTCGACCATTATTGCCGACTCCAAGTCTGGGGTTTCGGGTGCAGGCCGGGGCGC
CAAGGTAGAGAACCTTTACTGCGAAGTGAATGACGGGTTCAAGGCATACGGGGTGGGTGGAGTGCACCGGCATATCCCCG
AAATCGAGCAGGAGTTGTCGCTTCTGGCTGGTGGGCCGATCACCATCACCTTCACTCCCCACCTGGTTCCCATGGACCGG
GGAATCCTCTCCACCATCTACGCGCGGCTTACAGGCACTGACTCCGTCGCCGAACTGGTGAAGCTCTATGCTGAATTCTA
CGAAGGGGAGCCCTTTGTCCGTGTGCTTCCCGCCGGAAACGTCCCATCCACTGCTCACGTGCGTGGCTCCAATTTCTGCG
ACATCGGGTTGGCTGTGGACAGTCGCACTGGGCGGGTCATCGTGGTTTCCGCCATCGATAACCTCGTGAAAGGTGCCGCC
GGCCAAGCCGTGCAGAACATGAACATTATGTACGGCTTCCCTGAGACGATGGGGCTGGAAGGGCTCCCCCTTTTTCCCTG
A

Upstream 100 bases:

>100_bases
AGGGGAAAATCCATTCGGGTTTTCCCCTTTTGCTTTGCCAGAGTTTGCCCTATACTTTTGATACTTCGTGTCAGCCACCT
TTTTTCTCAGGAGTTTGCCT

Downstream 100 bases:

>100_bases
CGGGTATCTATGCCGTTTCTTCCAACCACAAGAGCCGAGGCGTTAAAACGGGGATGGCACGAACTTGACGTCGTTTTTGT
TACCGGTGACGCCTATATCG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLNVAVVGASGYTGVELLRLLYCHPEVAVTCITSEQSAGRPVAAVFPTLRSRYTQVLENLEPVKVAQKADLIFTALPHKA
AMEVVPTFLELGKRVVDLSADYRFNDPAVYEKWYEPHMNPENLKEAVYGLPEIRREKIGDAWLVGNPGCYPTSVILGLMP
LLKKRLIDPSTIIADSKSGVSGAGRGAKVENLYCEVNDGFKAYGVGGVHRHIPEIEQELSLLAGGPITITFTPHLVPMDR
GILSTIYARLTGTDSVAELVKLYAEFYEGEPFVRVLPAGNVPSTAHVRGSNFCDIGLAVDSRTGRVIVVSAIDNLVKGAA
GQAVQNMNIMYGFPETMGLEGLPLFP

Sequences:

>Translated_346_residues
MLNVAVVGASGYTGVELLRLLYCHPEVAVTCITSEQSAGRPVAAVFPTLRSRYTQVLENLEPVKVAQKADLIFTALPHKA
AMEVVPTFLELGKRVVDLSADYRFNDPAVYEKWYEPHMNPENLKEAVYGLPEIRREKIGDAWLVGNPGCYPTSVILGLMP
LLKKRLIDPSTIIADSKSGVSGAGRGAKVENLYCEVNDGFKAYGVGGVHRHIPEIEQELSLLAGGPITITFTPHLVPMDR
GILSTIYARLTGTDSVAELVKLYAEFYEGEPFVRVLPAGNVPSTAHVRGSNFCDIGLAVDSRTGRVIVVSAIDNLVKGAA
GQAVQNMNIMYGFPETMGLEGLPLFP
>Mature_346_residues
MLNVAVVGASGYTGVELLRLLYCHPEVAVTCITSEQSAGRPVAAVFPTLRSRYTQVLENLEPVKVAQKADLIFTALPHKA
AMEVVPTFLELGKRVVDLSADYRFNDPAVYEKWYEPHMNPENLKEAVYGLPEIRREKIGDAWLVGNPGCYPTSVILGLMP
LLKKRLIDPSTIIADSKSGVSGAGRGAKVENLYCEVNDGFKAYGVGGVHRHIPEIEQELSLLAGGPITITFTPHLVPMDR
GILSTIYARLTGTDSVAELVKLYAEFYEGEPFVRVLPAGNVPSTAHVRGSNFCDIGLAVDSRTGRVIVVSAIDNLVKGAA
GQAVQNMNIMYGFPETMGLEGLPLFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=40.5797101449275, Blast_Score=218, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320913, Length=341, Percent_Identity=31.3782991202346, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_GEOMG (Q39Y23)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383576.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q39Y23
- SMR:   Q39Y23
- STRING:   Q39Y23
- GeneID:   3738955
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0608
- NMPDR:   fig|269799.3.peg.636
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q39Y23
- ProtClustDB:   PRK00436
- BioCyc:   GMET269799:GMET_0608-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37484; Mature: 37484

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVAVVGASGYTGVELLRLLYCHPEVAVTCITSEQSAGRPVAAVFPTLRSRYTQVLENL
CCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
EPVKVAQKADLIFTALPHKAAMEVVPTFLELGKRVVDLSADYRFNDPAVYEKWYEPHMNP
CHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCHHEEECCCCCCCCCCHHHHHHCCCCCCH
ENLKEAVYGLPEIRREKIGDAWLVGNPGCYPTSVILGLMPLLKKRLIDPSTIIADSKSGV
HHHHHHHHCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCC
SGAGRGAKVENLYCEVNDGFKAYGVGGVHRHIPEIEQELSLLAGGPITITFTPHLVPMDR
CCCCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
GILSTIYARLTGTDSVAELVKLYAEFYEGEPFVRVLPAGNVPSTAHVRGSNFCDIGLAVD
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEE
SRTGRVIVVSAIDNLVKGAAGQAVQNMNIMYGFPETMGLEGLPLFP
CCCCCEEEEHHHHHHHHCCCCHHHHCCEEEEECCHHCCCCCCCCCC
>Mature Secondary Structure
MLNVAVVGASGYTGVELLRLLYCHPEVAVTCITSEQSAGRPVAAVFPTLRSRYTQVLENL
CCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
EPVKVAQKADLIFTALPHKAAMEVVPTFLELGKRVVDLSADYRFNDPAVYEKWYEPHMNP
CHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCHHEEECCCCCCCCCCHHHHHHCCCCCCH
ENLKEAVYGLPEIRREKIGDAWLVGNPGCYPTSVILGLMPLLKKRLIDPSTIIADSKSGV
HHHHHHHHCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCC
SGAGRGAKVENLYCEVNDGFKAYGVGGVHRHIPEIEQELSLLAGGPITITFTPHLVPMDR
CCCCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
GILSTIYARLTGTDSVAELVKLYAEFYEGEPFVRVLPAGNVPSTAHVRGSNFCDIGLAVD
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEE
SRTGRVIVVSAIDNLVKGAAGQAVQNMNIMYGFPETMGLEGLPLFP
CCCCCEEEEHHHHHHHHCCCCHHHHCCEEEEECCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA