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The map label for this gene is asd [H]

Identifier: 78221825

GI number: 78221825

Start: 675149

End: 676168

Strand: Direct

Name: asd [H]

Synonym: Gmet_0604

Alternate gene names: 78221825

Gene position: 675149-676168 (Clockwise)

Preceding gene: 78221824

Following gene: 78221826

Centisome position: 16.89

GC content: 61.08

Gene sequence:

>1020_bases
ATGGCAAAACTGTGGAACGTGGCCGTCGTCGGCGCCACTGGCGCCGTCGGTGGCCAGATGATCGAATGCCTCGAAGAGCG
CAACTTCCCTGTGGGGAAGATCCGCTACCTGGCCAGTGCCCGGAGCGCCGGCGAGGTGCTGGAGTTCAAGGGAAAGCCGG
TGATGGTGGAAGAGCTGACCCGCGACTCCTTTGAGGGGATCGACATCGCCCTCTTTTCGGCTGGCGGCGACCGTTCCCGG
GATTTCTGTCCCGCGGCGGCAGCTGCCGGCGCCGTTTGTATCGACAACTCCAGTGCCTGGCGGATGGATCCGGACGTGCC
GCTGGTGGTTCCCGAGGTGAATCCCCACGCCATCGCCGACTACCGGAAGAAGGGTATCATCGCCAACCCCAACTGCTCCA
CCATCCAGATGGTGGTGGCCCTGAAGCCGCTCCACGACCACGCTGTCATCAGGCGGATCGTGGTCTCCACCTACCAGGCT
GTTTCCGGCACCGGCAAGAAAGCTATTGAAGAGCTACAGAAACAGGTGGTCACCCTTTTTCAGGGGAAGTCGCCGGAAGT
GGCGACCTACCCCCACCAGATCGCCTTCAACTGCCTTCCTCAGATCGATTCCTTCGGTGACAACGGTTATACCAAGGAAG
AGATGAAGATGGTGCACGAAACCCGGAAGATTCTTGAGGCGAACATCGGGGTAACCGCCACTGCAGTTCGAGTGCCGGTC
TTCTACGGCCACTCCGAGTCAGTGAATATCGAAACCGAGAACAAGCTGACCGTGGCCACGGCCCGCGAACTTCTGGCAAA
GGCGCCCGGGGTGGAGCTGGTGGACGATCCGGCCACGTCATCCTATCCCATGGCCATCGACGCTGCCGGCCAGGACCTGA
CCCTCGTGGGGCGAATCCGTGAGGACGAGTCCATCGCCAACGGCCTCAACCTCTGGGTGGTGGCGGACAATATCCGCAAG
GGTGCGGCCACGAATGCCGTCCAAATCGCCGAGATTCTGATCGAAAAGTATCTCAGGTAG

Upstream 100 bases:

>100_bases
CCCCCAGTACATGCAGGCCTTCACCTGCGGCGATCAACTCCTCTGGGGGGCTGCCGAGCCCCTGCGCCGGATGCTCCGTA
TCCTCGTGGAGAAATAAGTA

Downstream 100 bases:

>100_bases
GGCCTGTTCGTATATCCCCCAGCCGGGACGCATGGCAACATGTCACCATGAGCGGGACGCCCTCCAGGGCGTCCTTGATT
TTTATGCATACCATTAAACT

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAKLWNVAVVGATGAVGGQMIECLEERNFPVGKIRYLASARSAGEVLEFKGKPVMVEELTRDSFEGIDIALFSAGGDRSR
DFCPAAAAAGAVCIDNSSAWRMDPDVPLVVPEVNPHAIADYRKKGIIANPNCSTIQMVVALKPLHDHAVIRRIVVSTYQA
VSGTGKKAIEELQKQVVTLFQGKSPEVATYPHQIAFNCLPQIDSFGDNGYTKEEMKMVHETRKILEANIGVTATAVRVPV
FYGHSESVNIETENKLTVATARELLAKAPGVELVDDPATSSYPMAIDAAGQDLTLVGRIREDESIANGLNLWVVADNIRK
GAATNAVQIAEILIEKYLR

Sequences:

>Translated_339_residues
MAKLWNVAVVGATGAVGGQMIECLEERNFPVGKIRYLASARSAGEVLEFKGKPVMVEELTRDSFEGIDIALFSAGGDRSR
DFCPAAAAAGAVCIDNSSAWRMDPDVPLVVPEVNPHAIADYRKKGIIANPNCSTIQMVVALKPLHDHAVIRRIVVSTYQA
VSGTGKKAIEELQKQVVTLFQGKSPEVATYPHQIAFNCLPQIDSFGDNGYTKEEMKMVHETRKILEANIGVTATAVRVPV
FYGHSESVNIETENKLTVATARELLAKAPGVELVDDPATSSYPMAIDAAGQDLTLVGRIREDESIANGLNLWVVADNIRK
GAATNAVQIAEILIEKYLR
>Mature_338_residues
AKLWNVAVVGATGAVGGQMIECLEERNFPVGKIRYLASARSAGEVLEFKGKPVMVEELTRDSFEGIDIALFSAGGDRSRD
FCPAAAAAGAVCIDNSSAWRMDPDVPLVVPEVNPHAIADYRKKGIIANPNCSTIQMVVALKPLHDHAVIRRIVVSTYQAV
SGTGKKAIEELQKQVVTLFQGKSPEVATYPHQIAFNCLPQIDSFGDNGYTKEEMKMVHETRKILEANIGVTATAVRVPVF
YGHSESVNIETENKLTVATARELLAKAPGVELVDDPATSSYPMAIDAAGQDLTLVGRIREDESIANGLNLWVVADNIRKG
AATNAVQIAEILIEKYLR

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=39.766081871345, Blast_Score=237, Evalue=8e-64,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=26.8361581920904, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320362, Length=388, Percent_Identity=28.0927835051546, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36630; Mature: 36499

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLWNVAVVGATGAVGGQMIECLEERNFPVGKIRYLASARSAGEVLEFKGKPVMVEELT
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCEEEHHHHH
RDSFEGIDIALFSAGGDRSRDFCPAAAAAGAVCIDNSSAWRMDPDVPLVVPEVNPHAIAD
CCCCCCCEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCEEECCCCCEEEECCCCHHHHH
YRKKGIIANPNCSTIQMVVALKPLHDHAVIRRIVVSTYQAVSGTGKKAIEELQKQVVTLF
HHHCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QGKSPEVATYPHQIAFNCLPQIDSFGDNGYTKEEMKMVHETRKILEANIGVTATAVRVPV
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
FYGHSESVNIETENKLTVATARELLAKAPGVELVDDPATSSYPMAIDAAGQDLTLVGRIR
EECCCCEEEEECCCCEEHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCCEEEEEECC
EDESIANGLNLWVVADNIRKGAATNAVQIAEILIEKYLR
CCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKLWNVAVVGATGAVGGQMIECLEERNFPVGKIRYLASARSAGEVLEFKGKPVMVEELT
CCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCEEEHHHHH
RDSFEGIDIALFSAGGDRSRDFCPAAAAAGAVCIDNSSAWRMDPDVPLVVPEVNPHAIAD
CCCCCCCEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCEEECCCCCEEEECCCCHHHHH
YRKKGIIANPNCSTIQMVVALKPLHDHAVIRRIVVSTYQAVSGTGKKAIEELQKQVVTLF
HHHCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QGKSPEVATYPHQIAFNCLPQIDSFGDNGYTKEEMKMVHETRKILEANIGVTATAVRVPV
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
FYGHSESVNIETENKLTVATARELLAKAPGVELVDDPATSSYPMAIDAAGQDLTLVGRIR
EECCCCEEEEECCCCEEHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCCEEEEEECC
EDESIANGLNLWVVADNIRKGAATNAVQIAEILIEKYLR
CCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]