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The map label for this gene is tal

Identifier: 78221718

GI number: 78221718

Start: 541064

End: 541708

Strand: Direct

Name: tal

Synonym: Gmet_0497

Alternate gene names: 78221718

Gene position: 541064-541708 (Clockwise)

Preceding gene: 78221717

Following gene: 78221724

Centisome position: 13.54

GC content: 62.64

Gene sequence:

>645_bases
ATGAAGTTTTTCATCGACACCGCAGACGTGAACGAAATCCGCGAGGCCCACGAGCTGGGGCTCGTGGACGGCGTCACCAC
CAACCCTTCGCTCATCGCCAAATCGGGACGCAAGTTCGAGGAGGTCATCAAGGAGATCACCGGCATCGTTGACGGCCCCA
TCTCCGCCGAGGTGGTCTCCCTGGACCACGACGGCATGATCCGCGAGGCCGAGGAGCTGGCCGCGATCCACAAGAACATC
GTCATCAAGCTCCCCATGACCCCGGAAGGGCTCAAGGCCTGCACCACCCTCACGAAGAAGGGGATCAAGACCAACGTGAC
CCTCATCTTCACCGCCATGCAGGCCCTTCTGGCCGCCAAGGCGGGCGCCACCTACGTCTCCCCCTTCGTGGGGCGCCTCG
ACGACATCTCCCAGGACGGCATGGGGATCATCGACGACATCAAGACCATCTTCGACAACTACGGCTACACCGCCGAGATC
ATCGTGGCCAGCGTCCGGAACCCCATCCACGTCCTGAACGCTGCCCTCATCGGCGCCGACATCGCCACCATCCCCTACTC
GGTCATGCTCCAACTGGCCAAGCACCCCCTCACCGACGCCGGCATCGAGCGGTTCCTGAAGGACTGGGAGAAGGTGCCGA
AGTAA

Upstream 100 bases:

>100_bases
AACGGATCCATTTCTGCTCCATGGCCTGCCTGGAGAAGTACCAGGCCGGCCTTGAGCATGCAGGCACCACCCATAACCAA
TCAAACCCGGAGGAACGAAA

Downstream 100 bases:

>100_bases
GGTTTTCCCTGTATTATTGAAAAAAACCCCGACGGTGGATGCTGTCGGGGTTTTTTTCATGCTGTGAAAACCGTTCGTAG
GCTTCAGAGGTGCTCTAGTT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKFFIDTADVNEIREAHELGLVDGVTTNPSLIAKSGRKFEEVIKEITGIVDGPISAEVVSLDHDGMIREAEELAAIHKNI
VIKLPMTPEGLKACTTLTKKGIKTNVTLIFTAMQALLAAKAGATYVSPFVGRLDDISQDGMGIIDDIKTIFDNYGYTAEI
IVASVRNPIHVLNAALIGADIATIPYSVMLQLAKHPLTDAGIERFLKDWEKVPK

Sequences:

>Translated_214_residues
MKFFIDTADVNEIREAHELGLVDGVTTNPSLIAKSGRKFEEVIKEITGIVDGPISAEVVSLDHDGMIREAEELAAIHKNI
VIKLPMTPEGLKACTTLTKKGIKTNVTLIFTAMQALLAAKAGATYVSPFVGRLDDISQDGMGIIDDIKTIFDNYGYTAEI
IVASVRNPIHVLNAALIGADIATIPYSVMLQLAKHPLTDAGIERFLKDWEKVPK
>Mature_214_residues
MKFFIDTADVNEIREAHELGLVDGVTTNPSLIAKSGRKFEEVIKEITGIVDGPISAEVVSLDHDGMIREAEELAAIHKNI
VIKLPMTPEGLKACTTLTKKGIKTNVTLIFTAMQALLAAKAGATYVSPFVGRLDDISQDGMGIIDDIKTIFDNYGYTAEI
IVASVRNPIHVLNAALIGADIATIPYSVMLQLAKHPLTDAGIERFLKDWEKVPK

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=173, Percent_Identity=31.7919075144509, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI87081788, Length=212, Percent_Identity=33.0188679245283, Blast_Score=133, Evalue=7e-33,
Organism=Escherichia coli, GI1790382, Length=211, Percent_Identity=36.0189573459716, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788807, Length=242, Percent_Identity=30.1652892561983, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786189, Length=185, Percent_Identity=32.972972972973, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25153750, Length=244, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321480, Length=171, Percent_Identity=30.9941520467836, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323386, Length=138, Percent_Identity=35.5072463768116, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=31.9767441860465, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_GEOMG (Q39YD4)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383465.1
- HSSP:   Q9WYD1
- ProteinModelPortal:   Q39YD4
- SMR:   Q39YD4
- STRING:   Q39YD4
- GeneID:   3738330
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0497
- NMPDR:   fig|269799.3.peg.525
- eggNOG:   COG0176
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q39YD4
- ProtClustDB:   PRK01362
- BioCyc:   GMET269799:GMET_0497-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23228; Mature: 23228

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFIDTADVNEIREAHELGLVDGVTTNPSLIAKSGRKFEEVIKEITGIVDGPISAEVVS
CEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEE
LDHDGMIREAEELAAIHKNIVIKLPMTPEGLKACTTLTKKGIKTNVTLIFTAMQALLAAK
ECCCCHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AGATYVSPFVGRLDDISQDGMGIIDDIKTIFDNYGYTAEIIVASVRNPIHVLNAALIGAD
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCH
IATIPYSVMLQLAKHPLTDAGIERFLKDWEKVPK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFFIDTADVNEIREAHELGLVDGVTTNPSLIAKSGRKFEEVIKEITGIVDGPISAEVVS
CEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEE
LDHDGMIREAEELAAIHKNIVIKLPMTPEGLKACTTLTKKGIKTNVTLIFTAMQALLAAK
ECCCCHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AGATYVSPFVGRLDDISQDGMGIIDDIKTIFDNYGYTAEIIVASVRNPIHVLNAALIGAD
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCH
IATIPYSVMLQLAKHPLTDAGIERFLKDWEKVPK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA