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The map label for this gene is ppaC [H]

Identifier: 78221724

GI number: 78221724

Start: 545216

End: 546862

Strand: Direct

Name: ppaC [H]

Synonym: Gmet_0503

Alternate gene names: 78221724

Gene position: 545216-546862 (Clockwise)

Preceding gene: 78221718

Following gene: 78221725

Centisome position: 13.64

GC content: 65.27

Gene sequence:

>1647_bases
ATGGATAAGCAGATTTACGTGGTTGGACACCGGAACCCCGACACCGACTCCGTCGCCTCGGCCCTGGCCTACGCGGCCCT
CAAGAACCGTCAGGGACAGATGAACGTGACCGCCGCCATGGCCGGCGAGCCGAACCCCCAGACCCGCTACATTCTGGAAC
GGCTCGGGATCGAGGCGCCGATCTACCTGGCCGACGTCCATCCCAAGGTCTGCCACGTCATCAACCGCCAGCCGGTGACG
ACCGTCAGCAGTACCCCCCTGCGGGATGCTCTGGGGATCTTTCACAAGCACGGCATCAGGGTATTGCCGGTGGTTGACGA
GGGCGGCGCGCCCATGGGGCTCGTGTCGCTCCTCAAACTCTCCGAGAAGTACCTGGTGGCCGGCACCGACCGAAAGCGGG
GGGTCGACGCCTCGCTCCGCACCCTGGCCTCCTGCCTGGACGGCACCTTCCTTACCGGTGCCCCGACCGACGAGGTGGAA
CACCTCCATCTCTTCATCGGCGCCATGCTGGAGGAGTCGTTTTCGAGCCACATCGAGGGGTATGACCCCGCATCGCTCCT
GATCATGACCGGCGACCGCCGCAGCATCCAGCAGGCGGCCATCGAACGGGGGGTGCGGCTCCTGGTGGTAACCGGCGGCT
TCCCCTTGGCCGATGGGCTGCGGGAGCGGGCACAGGAGCAGGGGGTGACGGTCATCTCTTCACCTCACGATACCGCCACC
GCCGCCGGCCTGGCCCGCCTCTCCACCCCTCTCTTCCACTTTGTGGAGGCGAAGTTCGAGAAGATTGGAGTGGCCGAGCC
CCTGGAGCACCTGCGCCTCAAGCTTCTCCACTCGGGGGAGCCGGCGGTGATCGCCGTGGAGGAGGATGGCACCATCGCCG
GCGTCGCCACCAAGTCGTCGCTCCTGGCGCAGATTCCCTACTCCCTCATCCTCGTGGATCACAACGAGCTGGCCCAGTCG
GTCCCCGGGGCCGAAGTGGTGGAGATTCTGGAGGTGATCGACCATCACAAGCTGGGGAACCCCCCCACGAATCAGCCGAT
TACCTTCATGGCGGCACCGGTGGGGAGCACCTGCACCGTGGTGGCCTCCCTCTACCGGGAGCGGGGGATCGAGCCCGACC
AGAAGGTGGCGGCGCTCCTTCTGGCCGGGGTCCTGTCCGACACGGTCATCCTCAAGTCCCCCACAACCACCAGCCGGGAC
CAGGAAATCGTCCGGTGGCTCGAAGAGCGGGCCGGCCTCGATCACGTGGTCTTTGGCAAGGACATCTTCTCCGCCTGCGG
CGGCTTCTCGGCCCACGGCACCCCGGAGAAGGCGATCCGGGCCGATTTCAAGCACTTCACCGCCGGAGACACCCTCTTTG
GCGTGGGGCAGGTGGAGGTGGTGGGGTTCGACGAGTTCTTCGACCTGAAGGAGACCCTCCGGGAGACCCTGAGGAAGGTG
AAGGAGGCGGACCGGCTCCACCTGGCCGGCCTCATGGTGACCGACATCTACAGCGAGACGACGCTTTTCCTGGCCGAAGG
GAAGAACGAGCTGGCCCACATCATGGGGTATCCCCAGGTGGAACCCCACCTCTACGAGTTGAAGGGGGTCATGTCCCGCA
AGAAGCAGATGGTGCCGCATCTCTTGAAAGTACTGAGGAAACTCTAG

Upstream 100 bases:

>100_bases
ATGATCTGTTGCATGGGAAAATGTCCTTCCGTGGGGTTAGGTGAAGCACATTTTTATAGCACAGTTCGGGCCATTGAGGC
CAGAAAAAGCAGGAGAATCA

Downstream 100 bases:

>100_bases
AGCGATGAATTTTCTCGAACGTTTGAACAGCGAAGTCCTCGTGGGGGACGGTGCCATCGGCACCATGCTCTATGCCAAGG
GGGTCTCCCTCGACGCCAAC

Product: putative manganese-dependent inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MDKQIYVVGHRNPDTDSVASALAYAALKNRQGQMNVTAAMAGEPNPQTRYILERLGIEAPIYLADVHPKVCHVINRQPVT
TVSSTPLRDALGIFHKHGIRVLPVVDEGGAPMGLVSLLKLSEKYLVAGTDRKRGVDASLRTLASCLDGTFLTGAPTDEVE
HLHLFIGAMLEESFSSHIEGYDPASLLIMTGDRRSIQQAAIERGVRLLVVTGGFPLADGLRERAQEQGVTVISSPHDTAT
AAGLARLSTPLFHFVEAKFEKIGVAEPLEHLRLKLLHSGEPAVIAVEEDGTIAGVATKSSLLAQIPYSLILVDHNELAQS
VPGAEVVEILEVIDHHKLGNPPTNQPITFMAAPVGSTCTVVASLYRERGIEPDQKVAALLLAGVLSDTVILKSPTTTSRD
QEIVRWLEERAGLDHVVFGKDIFSACGGFSAHGTPEKAIRADFKHFTAGDTLFGVGQVEVVGFDEFFDLKETLRETLRKV
KEADRLHLAGLMVTDIYSETTLFLAEGKNELAHIMGYPQVEPHLYELKGVMSRKKQMVPHLLKVLRKL

Sequences:

>Translated_548_residues
MDKQIYVVGHRNPDTDSVASALAYAALKNRQGQMNVTAAMAGEPNPQTRYILERLGIEAPIYLADVHPKVCHVINRQPVT
TVSSTPLRDALGIFHKHGIRVLPVVDEGGAPMGLVSLLKLSEKYLVAGTDRKRGVDASLRTLASCLDGTFLTGAPTDEVE
HLHLFIGAMLEESFSSHIEGYDPASLLIMTGDRRSIQQAAIERGVRLLVVTGGFPLADGLRERAQEQGVTVISSPHDTAT
AAGLARLSTPLFHFVEAKFEKIGVAEPLEHLRLKLLHSGEPAVIAVEEDGTIAGVATKSSLLAQIPYSLILVDHNELAQS
VPGAEVVEILEVIDHHKLGNPPTNQPITFMAAPVGSTCTVVASLYRERGIEPDQKVAALLLAGVLSDTVILKSPTTTSRD
QEIVRWLEERAGLDHVVFGKDIFSACGGFSAHGTPEKAIRADFKHFTAGDTLFGVGQVEVVGFDEFFDLKETLRETLRKV
KEADRLHLAGLMVTDIYSETTLFLAEGKNELAHIMGYPQVEPHLYELKGVMSRKKQMVPHLLKVLRKL
>Mature_548_residues
MDKQIYVVGHRNPDTDSVASALAYAALKNRQGQMNVTAAMAGEPNPQTRYILERLGIEAPIYLADVHPKVCHVINRQPVT
TVSSTPLRDALGIFHKHGIRVLPVVDEGGAPMGLVSLLKLSEKYLVAGTDRKRGVDASLRTLASCLDGTFLTGAPTDEVE
HLHLFIGAMLEESFSSHIEGYDPASLLIMTGDRRSIQQAAIERGVRLLVVTGGFPLADGLRERAQEQGVTVISSPHDTAT
AAGLARLSTPLFHFVEAKFEKIGVAEPLEHLRLKLLHSGEPAVIAVEEDGTIAGVATKSSLLAQIPYSLILVDHNELAQS
VPGAEVVEILEVIDHHKLGNPPTNQPITFMAAPVGSTCTVVASLYRERGIEPDQKVAALLLAGVLSDTVILKSPTTTSRD
QEIVRWLEERAGLDHVVFGKDIFSACGGFSAHGTPEKAIRADFKHFTAGDTLFGVGQVEVVGFDEFFDLKETLRETLRKV
KEADRLHLAGLMVTDIYSETTLFLAEGKNELAHIMGYPQVEPHLYELKGVMSRKKQMVPHLLKVLRKL

Specific function: Unknown

COG id: COG1227

COG function: function code C; Inorganic pyrophosphatase/exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001807
- InterPro:   IPR000644
- InterPro:   IPR004097
- InterPro:   IPR010766
- InterPro:   IPR001667 [H]

Pfam domain/function: PF00571 CBS; PF01368 DHH; PF02833 DHHA2; PF07085 DRTGG [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 59609; Mature: 59609

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQIYVVGHRNPDTDSVASALAYAALKNRQGQMNVTAAMAGEPNPQTRYILERLGIEAP
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
IYLADVHPKVCHVINRQPVTTVSSTPLRDALGIFHKHGIRVLPVVDEGGAPMGLVSLLKL
EEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
SEKYLVAGTDRKRGVDASLRTLASCLDGTFLTGAPTDEVEHLHLFIGAMLEESFSSHIEG
CCCEEEECCCCCCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
YDPASLLIMTGDRRSIQQAAIERGVRLLVVTGGFPLADGLRERAQEQGVTVISSPHDTAT
CCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHH
AAGLARLSTPLFHFVEAKFEKIGVAEPLEHLRLKLLHSGEPAVIAVEEDGTIAGVATKSS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHH
LLAQIPYSLILVDHNELAQSVPGAEVVEILEVIDHHKLGNPPTNQPITFMAAPVGSTCTV
HHHHCCEEEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHH
VASLYRERGIEPDQKVAALLLAGVLSDTVILKSPTTTSRDQEIVRWLEERAGLDHVVFGK
HHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECH
DIFSACGGFSAHGTPEKAIRADFKHFTAGDTLFGVGQVEVVGFDEFFDLKETLRETLRKV
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHH
KEADRLHLAGLMVTDIYSETTLFLAEGKNELAHIMGYPQVEPHLYELKGVMSRKKQMVPH
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LLKVLRKL
HHHHHHCC
>Mature Secondary Structure
MDKQIYVVGHRNPDTDSVASALAYAALKNRQGQMNVTAAMAGEPNPQTRYILERLGIEAP
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
IYLADVHPKVCHVINRQPVTTVSSTPLRDALGIFHKHGIRVLPVVDEGGAPMGLVSLLKL
EEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
SEKYLVAGTDRKRGVDASLRTLASCLDGTFLTGAPTDEVEHLHLFIGAMLEESFSSHIEG
CCCEEEECCCCCCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
YDPASLLIMTGDRRSIQQAAIERGVRLLVVTGGFPLADGLRERAQEQGVTVISSPHDTAT
CCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHH
AAGLARLSTPLFHFVEAKFEKIGVAEPLEHLRLKLLHSGEPAVIAVEEDGTIAGVATKSS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHH
LLAQIPYSLILVDHNELAQSVPGAEVVEILEVIDHHKLGNPPTNQPITFMAAPVGSTCTV
HHHHCCEEEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHH
VASLYRERGIEPDQKVAALLLAGVLSDTVILKSPTTTSRDQEIVRWLEERAGLDHVVFGK
HHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECH
DIFSACGGFSAHGTPEKAIRADFKHFTAGDTLFGVGQVEVVGFDEFFDLKETLRETLRKV
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHH
KEADRLHLAGLMVTDIYSETTLFLAEGKNELAHIMGYPQVEPHLYELKGVMSRKKQMVPH
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LLKVLRKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]