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The map label for this gene is cbiD

Identifier: 78221699

GI number: 78221699

Start: 523536

End: 524645

Strand: Direct

Name: cbiD

Synonym: Gmet_0478

Alternate gene names: 78221699

Gene position: 523536-524645 (Clockwise)

Preceding gene: 78221698

Following gene: 78221700

Centisome position: 13.1

GC content: 66.85

Gene sequence:

>1110_bases
ATGAACACGAAACCACTCCGTCACGGTTACACCACCGGCGCCTGTGCCGCCGCCGCCGCCAAGGGGGCAGCCCGGATGCT
CCGGGAGCAGCGTCCCGTGGAGGAGGTGGAGCTCGTCCTTCCCAAAGGAGAGCGGGTCGCTTTTCGCCTCCATGGCCAGG
AATTCGATGACAGCGCCGCCTCCTGCTTCGTGGTGAAGGACGCGGGGGACGACCCCGACGTGACCAACGGCGCCGAGATC
CACGCCCGGGTCCGGCGCGAGCCCCTGAACCGCTCCGGCGCCCGGACCATGGTCTTCGTGGATGGCGGGAAGGGGGTCGG
CACGGTGACCAAACCGGGGCTCGGGGTGGGGGTGGGGAATCCGGCCATCAACCCGGTGCCGATGCGGATGATCACCGAGG
GGGTGAAGGAAGAGTTCTCCGTCGTCTGCCTTCCCCAGGTTCTCCACGTCACCATCTCCATCCCCAACGGCGAGGAACTG
GCGAAGAAGACCCTCAATGCCCGCCTCGGCATCGTGGGGGGGCTCTCCATCCTCGGCACCACCGGCATCGTGCGCCCCAT
CTCCGCCAAGGCCTGGACCGATACCCTCGATGCGGCCCTGGACGTGGCCCGGGCCTGCGGCTGCGAAACGATTGTCCTCT
CCACGGGGAGGACCAGCGAGTTGGTGGCTATACATGCCGGGATCGGGGACCGGGGACCGGGGACCGGGAAAACCTTGCCC
GAAGAGGCCTATGTGATGATGGGGGACCACGTGGGGTACGCGCTCCGGGCCTGCGCCCGCAAGGGGGTGCGTCACGTTAT
CCTGGTGGGGCAGTTCGCCAAGCTCCTCAAGATTGCCTGCGGCCACGAGCAGACCCACGTCTCCTCCTCGGAGCTGGATC
TGCAAATGCTGGCGGAGTGGCTTCACGAATTGGGTTCCCGGTCCCCGGTCCCCGGCCCCTGGTCCCGGTACAACACCGCC
CGCCAGGTGCTGGAGGAGTCGGGTAACGACTCGCTCTTCATGGAGCTCGTCTGTACCCGGGCCCGTGATGCGGCCCGGCG
CCTGGCCCCTTCCCTCGACATCAAGGTTTTGCTGGCAGGGTACGATTCAACGGTGCTATATTTCGGGTAA

Upstream 100 bases:

>100_bases
GGGGCGCAAGGGGGGGTCCAACGTGGCCGCTGCCGTGGTGAATGCGCTCCTGATCCTGGCGGAGGAGGCGGGGTAGGGTG
ACTCCTGCCGGCCACGTTCC

Downstream 100 bases:

>100_bases
AATTTCGGCATGGAAACCTTCGTCGGGGAGAATGTCATGACAGAGCCTCGTATCCATATCCCGCGAGACAGAATCATAGA
ATTCTGCCAGCGGTGGAAGA

Product: cobalamin (vitamin B12) biosynthesis CbiD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNTKPLRHGYTTGACAAAAAKGAARMLREQRPVEEVELVLPKGERVAFRLHGQEFDDSAASCFVVKDAGDDPDVTNGAEI
HARVRREPLNRSGARTMVFVDGGKGVGTVTKPGLGVGVGNPAINPVPMRMITEGVKEEFSVVCLPQVLHVTISIPNGEEL
AKKTLNARLGIVGGLSILGTTGIVRPISAKAWTDTLDAALDVARACGCETIVLSTGRTSELVAIHAGIGDRGPGTGKTLP
EEAYVMMGDHVGYALRACARKGVRHVILVGQFAKLLKIACGHEQTHVSSSELDLQMLAEWLHELGSRSPVPGPWSRYNTA
RQVLEESGNDSLFMELVCTRARDAARRLAPSLDIKVLLAGYDSTVLYFG

Sequences:

>Translated_369_residues
MNTKPLRHGYTTGACAAAAAKGAARMLREQRPVEEVELVLPKGERVAFRLHGQEFDDSAASCFVVKDAGDDPDVTNGAEI
HARVRREPLNRSGARTMVFVDGGKGVGTVTKPGLGVGVGNPAINPVPMRMITEGVKEEFSVVCLPQVLHVTISIPNGEEL
AKKTLNARLGIVGGLSILGTTGIVRPISAKAWTDTLDAALDVARACGCETIVLSTGRTSELVAIHAGIGDRGPGTGKTLP
EEAYVMMGDHVGYALRACARKGVRHVILVGQFAKLLKIACGHEQTHVSSSELDLQMLAEWLHELGSRSPVPGPWSRYNTA
RQVLEESGNDSLFMELVCTRARDAARRLAPSLDIKVLLAGYDSTVLYFG
>Mature_369_residues
MNTKPLRHGYTTGACAAAAAKGAARMLREQRPVEEVELVLPKGERVAFRLHGQEFDDSAASCFVVKDAGDDPDVTNGAEI
HARVRREPLNRSGARTMVFVDGGKGVGTVTKPGLGVGVGNPAINPVPMRMITEGVKEEFSVVCLPQVLHVTISIPNGEEL
AKKTLNARLGIVGGLSILGTTGIVRPISAKAWTDTLDAALDVARACGCETIVLSTGRTSELVAIHAGIGDRGPGTGKTLP
EEAYVMMGDHVGYALRACARKGVRHVILVGQFAKLLKIACGHEQTHVSSSELDLQMLAEWLHELGSRSPVPGPWSRYNTA
RQVLEESGNDSLFMELVCTRARDAARRLAPSLDIKVLLAGYDSTVLYFG

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_GEOMG (Q39YF3)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383446.1
- ProteinModelPortal:   Q39YF3
- SMR:   Q39YF3
- STRING:   Q39YF3
- GeneID:   3739845
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0478
- NMPDR:   fig|269799.3.peg.506
- eggNOG:   COG1903
- HOGENOM:   HBG705387
- OMA:   RRGWTTG
- ProtClustDB:   CLSK829046
- BioCyc:   GMET269799:GMET_0478-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 39352; Mature: 39352

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKPLRHGYTTGACAAAAAKGAARMLREQRPVEEVELVLPKGERVAFRLHGQEFDDSAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCC
SCFVVKDAGDDPDVTNGAEIHARVRREPLNRSGARTMVFVDGGKGVGTVTKPGLGVGVGN
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEECCC
PAINPVPMRMITEGVKEEFSVVCLPQVLHVTISIPNGEELAKKTLNARLGIVGGLSILGT
CCCCCCCHHHHHHHHHHHHEEEEECEEEEEEEECCCCHHHHHHHHHHHHHHEECHHHHCC
TGIVRPISAKAWTDTLDAALDVARACGCETIVLSTGRTSELVAIHAGIGDRGPGTGKTLP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCC
EEAYVMMGDHVGYALRACARKGVRHVILVGQFAKLLKIACGHEQTHVSSSELDLQMLAEW
CCCEEEECCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCHHCCCCHHCCHHHHHHH
LHELGSRSPVPGPWSRYNTARQVLEESGNDSLFMELVCTRARDAARRLAPSLDIKVLLAG
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
YDSTVLYFG
CCCEEEEEC
>Mature Secondary Structure
MNTKPLRHGYTTGACAAAAAKGAARMLREQRPVEEVELVLPKGERVAFRLHGQEFDDSAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCC
SCFVVKDAGDDPDVTNGAEIHARVRREPLNRSGARTMVFVDGGKGVGTVTKPGLGVGVGN
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEECCC
PAINPVPMRMITEGVKEEFSVVCLPQVLHVTISIPNGEELAKKTLNARLGIVGGLSILGT
CCCCCCCHHHHHHHHHHHHEEEEECEEEEEEEECCCCHHHHHHHHHHHHHHEECHHHHCC
TGIVRPISAKAWTDTLDAALDVARACGCETIVLSTGRTSELVAIHAGIGDRGPGTGKTLP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCC
EEAYVMMGDHVGYALRACARKGVRHVILVGQFAKLLKIACGHEQTHVSSSELDLQMLAEW
CCCEEEECCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCHHCCCCHHCCHHHHHHH
LHELGSRSPVPGPWSRYNTARQVLEESGNDSLFMELVCTRARDAARRLAPSLDIKVLLAG
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
YDSTVLYFG
CCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA