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The map label for this gene is cbiC [H]

Identifier: 78221698

GI number: 78221698

Start: 522867

End: 523511

Strand: Direct

Name: cbiC [H]

Synonym: Gmet_0477

Alternate gene names: 78221698

Gene position: 522867-523511 (Clockwise)

Preceding gene: 78221697

Following gene: 78221699

Centisome position: 13.08

GC content: 68.37

Gene sequence:

>645_bases
ATGTCGGTCCACCTCGCCCCCGAGGAGATCGAGGCCGAATCGTTCCGCCTCATCGATGAAGAAGTGGGAACCCATCACTG
GGGGCCTGCCGAGTGGCCGGTGGTGCGGCGGGCGATCCACACGAGCGCCGATTTCGACTACGTCCGCACCATGGTCTTCT
CCCCCCGGGCCGTTGCCCGTGGCGTGGCGGCCCTGCGACAAGGGCGGGGGATCGTCACCGACACCACCATGGCCCTGTCG
GGGATAGCCAAGCCGCGGCTCAAGCGTTTCGGCCTCGGCGCCGCCTGCTTCGTGGCCGACCCGGAGGTGGCCCGGGAGGC
GAAGGCGCTCGGCATTACCCGTTCTATTGTGGCCATGCGCAAGGGTGCGGCAGACGGAGGGAACGGCATCTTCGTCATCG
GCAACGCCCCCACGGCCCTCTTCGAACTGTTGCGTCTCATCCGCGAGGAAGGGGTGCGTCCGGCGCTGATCGTGGGGCTG
CCGGTGGGGTTCGTGGGGGCCGCAGAGAGCAAGGAGGCCCTTCTGGCCCTGGAGGATGAGTTTCCCGACATCCCCTTCAT
CACCAACCGGGGGCGCAAGGGGGGGTCCAACGTGGCCGCTGCCGTGGTGAATGCGCTCCTGATCCTGGCGGAGGAGGCGG
GGTAG

Upstream 100 bases:

>100_bases
TCGAATTCGCCATGGGGCCGCACCTTGGTGTTCACCGCAAGCTGGCCGAGGTGGAAGTGGAGCGGATCGCCGAGGCCCTC
ACCGCCACGGGGTGGCACTG

Downstream 100 bases:

>100_bases
GGTGACTCCTGCCGGCCACGTTCCATGAACACGAAACCACTCCGTCACGGTTACACCACCGGCGCCTGTGCCGCCGCCGC
CGCCAAGGGGGCAGCCCGGA

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSVHLAPEEIEAESFRLIDEEVGTHHWGPAEWPVVRRAIHTSADFDYVRTMVFSPRAVARGVAALRQGRGIVTDTTMALS
GIAKPRLKRFGLGAACFVADPEVAREAKALGITRSIVAMRKGAADGGNGIFVIGNAPTALFELLRLIREEGVRPALIVGL
PVGFVGAAESKEALLALEDEFPDIPFITNRGRKGGSNVAAAVVNALLILAEEAG

Sequences:

>Translated_214_residues
MSVHLAPEEIEAESFRLIDEEVGTHHWGPAEWPVVRRAIHTSADFDYVRTMVFSPRAVARGVAALRQGRGIVTDTTMALS
GIAKPRLKRFGLGAACFVADPEVAREAKALGITRSIVAMRKGAADGGNGIFVIGNAPTALFELLRLIREEGVRPALIVGL
PVGFVGAAESKEALLALEDEFPDIPFITNRGRKGGSNVAAAVVNALLILAEEAG
>Mature_213_residues
SVHLAPEEIEAESFRLIDEEVGTHHWGPAEWPVVRRAIHTSADFDYVRTMVFSPRAVARGVAALRQGRGIVTDTTMALSG
IAKPRLKRFGLGAACFVADPEVAREAKALGITRSIVAMRKGAADGGNGIFVIGNAPTALFELLRLIREEGVRPALIVGLP
VGFVGAAESKEALLALEDEFPDIPFITNRGRKGGSNVAAAVVNALLILAEEAG

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22718; Mature: 22587

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHLAPEEIEAESFRLIDEEVGTHHWGPAEWPVVRRAIHTSADFDYVRTMVFSPRAVAR
CCCCCCHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
GVAALRQGRGIVTDTTMALSGIAKPRLKRFGLGAACFVADPEVAREAKALGITRSIVAMR
HHHHHHHCCCCEEHHHHHHHHHCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
KGAADGGNGIFVIGNAPTALFELLRLIREEGVRPALIVGLPVGFVGAAESKEALLALEDE
HCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCC
FPDIPFITNRGRKGGSNVAAAVVNALLILAEEAG
CCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVHLAPEEIEAESFRLIDEEVGTHHWGPAEWPVVRRAIHTSADFDYVRTMVFSPRAVAR
CCCCCHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
GVAALRQGRGIVTDTTMALSGIAKPRLKRFGLGAACFVADPEVAREAKALGITRSIVAMR
HHHHHHHCCCCEEHHHHHHHHHCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
KGAADGGNGIFVIGNAPTALFELLRLIREEGVRPALIVGLPVGFVGAAESKEALLALEDE
HCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCC
FPDIPFITNRGRKGGSNVAAAVVNALLILAEEAG
CCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]