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The map label for this gene is gpmB [H]

Identifier: 78221690

GI number: 78221690

Start: 516304

End: 516909

Strand: Direct

Name: gpmB [H]

Synonym: Gmet_0469

Alternate gene names: 78221690

Gene position: 516304-516909 (Clockwise)

Preceding gene: 78221689

Following gene: 78221691

Centisome position: 12.92

GC content: 64.03

Gene sequence:

>606_bases
ATGACACCAAAAACACGGATTCATCTCATCCGCCACGGCGAAGTTGAAGGGGCCGGGCCGGTGCGTCGTTATAACGGCCA
TACCGACGTGGCCCTCTCGGAGCGGGGGCGGAGCCAGTACCACGCCATCAAGGAGCGCTTTGCGGACGCCCCCATAACGG
CCCTCTACACGAGCGATCTCCGGCGCTGCGCCTGGGGGGCCGAGGTGCTCGGCTCCCACCTGGGTCTCACCCCGGTGCGA
AAACCGGAGCTGCGGGAGATGGGGGTGGGGATCTGGGAGGGTAAGAGCTGGCCCGAGCTTATGGAGCAGTATCCTGCAGA
GTGGCAGGCCCGGCTCGACGACATCGTCAACTACCGGGTCCCCCAGGGGGAAAGTGTTCTCGACGTGCACGGCCGGGTGA
TGCCGGTCATCAATGACATCGTGGAGCGCCACCGGGGTGAGGAAGTCCTCGTGGTGGCCCACGGCGGGGTGAACCGGATC
ATCCTCCTGAACGCCATCGGCGCCCCCCTTTCGAGCCTTTTTGCCATCGAGCAGACCTACTGTTGCCTGAACATCATTGA
CTACTTCGCCGACGGCAACACCGTCGTGAAGCTGGTGAACGGCTGA

Upstream 100 bases:

>100_bases
GGCGGGGTGACCGGCGATGTCATCGGCTGTGCCAGTGAGTTGAACGAAATTATCTGCCTGCTGATTATTGTGGGCATGCA
GAAGATGTAAGGAAAGCGAC

Downstream 100 bases:

>100_bases
CGTCATGAAATCAATCATCATCGCAGCGCCCCACAGCGGGTCGGGCAAGACGACCATCACCCTCGGCATTATGGAGTGCC
TGAAGCGGCGCGGACTCACG

Product: phosphoglycerate/bisphosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTPKTRIHLIRHGEVEGAGPVRRYNGHTDVALSERGRSQYHAIKERFADAPITALYTSDLRRCAWGAEVLGSHLGLTPVR
KPELREMGVGIWEGKSWPELMEQYPAEWQARLDDIVNYRVPQGESVLDVHGRVMPVINDIVERHRGEEVLVVAHGGVNRI
ILLNAIGAPLSSLFAIEQTYCCLNIIDYFADGNTVVKLVNG

Sequences:

>Translated_201_residues
MTPKTRIHLIRHGEVEGAGPVRRYNGHTDVALSERGRSQYHAIKERFADAPITALYTSDLRRCAWGAEVLGSHLGLTPVR
KPELREMGVGIWEGKSWPELMEQYPAEWQARLDDIVNYRVPQGESVLDVHGRVMPVINDIVERHRGEEVLVVAHGGVNRI
ILLNAIGAPLSSLFAIEQTYCCLNIIDYFADGNTVVKLVNG
>Mature_200_residues
TPKTRIHLIRHGEVEGAGPVRRYNGHTDVALSERGRSQYHAIKERFADAPITALYTSDLRRCAWGAEVLGSHLGLTPVRK
PELREMGVGIWEGKSWPELMEQYPAEWQARLDDIVNYRVPQGESVLDVHGRVMPVINDIVERHRGEEVLVVAHGGVNRII
LLNAIGAPLSSLFAIEQTYCCLNIIDYFADGNTVVKLVNG

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758902, Length=164, Percent_Identity=35.9756097560976, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI118582286, Length=166, Percent_Identity=36.144578313253, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI64762445, Length=186, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI64762406, Length=186, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790856, Length=184, Percent_Identity=26.6304347826087, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786857, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145314, Length=173, Percent_Identity=32.9479768786127, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510917, Length=164, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71993390, Length=164, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322306, Length=173, Percent_Identity=33.5260115606936, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22460; Mature: 22329

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKTRIHLIRHGEVEGAGPVRRYNGHTDVALSERGRSQYHAIKERFADAPITALYTSDL
CCCCCEEEEEECCCCCCCCCCEECCCCCCEEEHHCCCHHHHHHHHHHCCCCCHHHHHHHH
RRCAWGAEVLGSHLGLTPVRKPELREMGVGIWEGKSWPELMEQYPAEWQARLDDIVNYRV
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEECCCCCHHHHHHCCHHHHHHHHHHHHCCC
PQGESVLDVHGRVMPVINDIVERHRGEEVLVVAHGGVNRIILLNAIGAPLSSLFAIEQTY
CCCCCEEHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHH
CCLNIIDYFADGNTVVKLVNG
HHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
TPKTRIHLIRHGEVEGAGPVRRYNGHTDVALSERGRSQYHAIKERFADAPITALYTSDL
CCCCEEEEEECCCCCCCCCCEECCCCCCEEEHHCCCHHHHHHHHHHCCCCCHHHHHHHH
RRCAWGAEVLGSHLGLTPVRKPELREMGVGIWEGKSWPELMEQYPAEWQARLDDIVNYRV
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEECCCCCHHHHHHCCHHHHHHHHHHHHCCC
PQGESVLDVHGRVMPVINDIVERHRGEEVLVVAHGGVNRIILLNAIGAPLSSLFAIEQTY
CCCCCEEHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHH
CCLNIIDYFADGNTVVKLVNG
HHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA