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The map label for this gene is cobP [H]

Identifier: 78221687

GI number: 78221687

Start: 513757

End: 514275

Strand: Direct

Name: cobP [H]

Synonym: Gmet_0466

Alternate gene names: 78221687

Gene position: 513757-514275 (Clockwise)

Preceding gene: 78221686

Following gene: 78221688

Centisome position: 12.85

GC content: 66.67

Gene sequence:

>519_bases
ATGGCGCCAGTGATTTTCATAACCGGGGGGGGCCGCAGCGGCAAGAGCCGGCTGGCCGAGCGCATCTCGGGGGGGTTCGG
CGCCCCCCTGGGCTACCTGGCCACCGGAACCGCCGGCGACGGGGAGATGGCGGAGCGGATTGCCCGCCACCGGCAGCGGC
GGGGTGACGACTGGACCACCATCGAAGAGCCGCTTGATCTTGCCGGCGTCCTCCGGGAGAACGACGGCCGCTTCAGCGCC
ATCCTCGTGGACTGTGTGACCCTCTGGCTCACGAATCTCCTTCTTGCCTGCGACGACCCTGCCCGGTGTGTGGCGCGAGT
CAAAGAGCTGACGTCGCTTTTCCCTCAGCTCACGACCCCGCTGGTCCTCGTTTCCAACGAGGTGGGGATGGGGATTGTTC
CCGAGAACCGGCTTGCCCGCCAGTTCCGCGACTTGGCCGGAGAGGCCAACGAGATGATCGCCGCCGCGGCCGGCGAGGTT
TACGTAACCTTCAGCGGACTGCCGTTGAGATTGAAGTGA

Upstream 100 bases:

>100_bases
GCTTCACAGGACCTCCGTGGAAGAGGCTCCGAGGCCCGGCGTTCGGCTTTTCACCGGTTTTTGGACCCCGCTTCCCTTCA
GGAGGCGGGGTTTTTCATTT

Downstream 100 bases:

>100_bases
ATGTGTAGGGGCGCTGCTTGCCGCACCCTTTGTGCAGTTGAAGAAGGGCGCGGCAAGCGGCGCCCCTACGAATAATCTTG
AAAAGAGGTACTCTATGACC

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAPVIFITGGGRSGKSRLAERISGGFGAPLGYLATGTAGDGEMAERIARHRQRRGDDWTTIEEPLDLAGVLRENDGRFSA
ILVDCVTLWLTNLLLACDDPARCVARVKELTSLFPQLTTPLVLVSNEVGMGIVPENRLARQFRDLAGEANEMIAAAAGEV
YVTFSGLPLRLK

Sequences:

>Translated_172_residues
MAPVIFITGGGRSGKSRLAERISGGFGAPLGYLATGTAGDGEMAERIARHRQRRGDDWTTIEEPLDLAGVLRENDGRFSA
ILVDCVTLWLTNLLLACDDPARCVARVKELTSLFPQLTTPLVLVSNEVGMGIVPENRLARQFRDLAGEANEMIAAAAGEV
YVTFSGLPLRLK
>Mature_171_residues
APVIFITGGGRSGKSRLAERISGGFGAPLGYLATGTAGDGEMAERIARHRQRRGDDWTTIEEPLDLAGVLRENDGRFSAI
LVDCVTLWLTNLLLACDDPARCVARVKELTSLFPQLTTPLVLVSNEVGMGIVPENRLARQFRDLAGEANEMIAAAAGEVY
VTFSGLPLRLK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=41.4364640883978, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18513; Mature: 18381

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVIFITGGGRSGKSRLAERISGGFGAPLGYLATGTAGDGEMAERIARHRQRRGDDWTT
CCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
IEEPLDLAGVLRENDGRFSAILVDCVTLWLTNLLLACDDPARCVARVKELTSLFPQLTTP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
LVLVSNEVGMGIVPENRLARQFRDLAGEANEMIAAAAGEVYVTFSGLPLRLK
EEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCEEEEC
>Mature Secondary Structure 
APVIFITGGGRSGKSRLAERISGGFGAPLGYLATGTAGDGEMAERIARHRQRRGDDWTT
CCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
IEEPLDLAGVLRENDGRFSAILVDCVTLWLTNLLLACDDPARCVARVKELTSLFPQLTTP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
LVLVSNEVGMGIVPENRLARQFRDLAGEANEMIAAAAGEVYVTFSGLPLRLK
EEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]