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The map label for this gene is uxaC [H]

Identifier: 78221672

GI number: 78221672

Start: 497403

End: 498824

Strand: Reverse

Name: uxaC [H]

Synonym: Gmet_0451

Alternate gene names: 78221672

Gene position: 498824-497403 (Counterclockwise)

Preceding gene: 78221673

Following gene: 78221671

Centisome position: 12.48

GC content: 54.01

Gene sequence:

>1422_bases
ATGACGATTAGGCGTAATTTCACGGCATCTGTAAGAGAAAACGCCCTTACCCTGTACGAGCGACATGCCTCCTTGCCAAT
CATTGACTATCACGGCCATCTGCCGCCGGCAAGGCTTGCCAGTAATGCCCACTTCAGGGATCTTTCGGAACTGTGGATCG
AAGGAGACCACTATAAATGGCGAGCCATGCGGATAGCCGGTGAGCGCGAGGATCTGTGCACCGGCTCAGCGTCGCCAAAA
GAACGGTTTGATGCGTGGGCTCGCACCATCACGCGGATGGCCTCAAGCCCAATGCAGGCGTGGTGCCAGATTGAGCTCAA
GCGGACTTTCGGCATAACGGCTCCGCTGACACCGTCTTCTGCAGAGTGCATATGGGAAGAGGCGAACTCGATGCTCGCGA
CCGAAAACTTCCGGCCACGGAAGTTACTGGCAAGAGCTGGCGTCGAAGTCCTCTGCACCACTGACGATCCAGCCGACCAG
TTGGAAGCGCACCGCCAACTTGTAGAAGATAAGGAGGTCTCTTTTCGGGTTTTCCCGACCTTTCGCCCTGACTCCGCGCT
TTGCCTCCACACCCGCCAGAATTTTCACGATTGGCGCTCACGGCTCGAAGCATGTTCCGGCATCGCAATAGAGTCGTTAC
AAACATTCATGGAGGCGCTTCGGGTCCGATATGAATTCTTCCACAAACTCGGATGCCGGGTCTCCGACCATGGGATGGAC
CGGTGCTACGCAACTCCTTGCTCGGACGCCGAAGCCACCACCATCTTCAGCCGGTTGCTTTTAAGTTCTTCCGATATCGA
CGCTGATGATCTCGAAAAATGGCGCAGTTGGTTCATGCGCCAGATCGCAGAATGGAATCACGAATCCGGCTGGACGATGA
TGTTGCACCTTGGGGCTCGCAGGAACAACAACACCCGAATTTTTTCATCATACGGCCTGGATGCAGGTTGCGACTCTATA
GGAGATTTCCCGCAGGGGGAGTCTCTCGTTGCGTTCCTCGATCAACTGGACACCTCCGAGCGGTTGCCGAAAACGATTCT
GTTCAATTCGAATCCCCGTGACACGTTAATGTTCGCGACCATTGCCGGAAGTTTTTGGGGAGAGGGAATTCGAGGGAAAG
TTCAGCACGGTCCCCCTTGGTGGTTTCTCGACCAGATATACGGCATAGAGGACCACCTGAACGCTCAATGCGCTGTTGGT
GTTCTCGGAACTTTCGTCGGCATGGCATCAGACTCCCGAAGTTTTCTCTCAACGGCCCGTCACGAATATTTCCGTAAAGC
CATAACGCTACGTTTGGCTGACGATCTGGAATCCGGTCTTTTCAACCCCGATCAGGTTGACATCGATGAGTTTTGCCGTG
ACCTTTTCTATGCTAATGCACAATCTTTCTTCGGATGGAAGGTAGCCCATGGGAATTCTTAG

Upstream 100 bases:

>100_bases
AAACTGGGTGATCTAGGCTCGACACAGTTGATCCGTTTTGTTCGACGCTGATGTCTAAGCGATTTGACACTGATTCTCAA
ATGCAGGAAAAGGAATCATC

Downstream 100 bases:

>100_bases
TGGCATGAACATCGTCGTTCTGGGGGCAAGCGGGGTCTTGGGGCGGGCCTTCGCCCAAGCAGCAACGGCAGTAGGGGCGG
CCTGCATCGTCGCGGGGCGA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTIRRNFTASVRENALTLYERHASLPIIDYHGHLPPARLASNAHFRDLSELWIEGDHYKWRAMRIAGEREDLCTGSASPK
ERFDAWARTITRMASSPMQAWCQIELKRTFGITAPLTPSSAECIWEEANSMLATENFRPRKLLARAGVEVLCTTDDPADQ
LEAHRQLVEDKEVSFRVFPTFRPDSALCLHTRQNFHDWRSRLEACSGIAIESLQTFMEALRVRYEFFHKLGCRVSDHGMD
RCYATPCSDAEATTIFSRLLLSSSDIDADDLEKWRSWFMRQIAEWNHESGWTMMLHLGARRNNNTRIFSSYGLDAGCDSI
GDFPQGESLVAFLDQLDTSERLPKTILFNSNPRDTLMFATIAGSFWGEGIRGKVQHGPPWWFLDQIYGIEDHLNAQCAVG
VLGTFVGMASDSRSFLSTARHEYFRKAITLRLADDLESGLFNPDQVDIDEFCRDLFYANAQSFFGWKVAHGNS

Sequences:

>Translated_473_residues
MTIRRNFTASVRENALTLYERHASLPIIDYHGHLPPARLASNAHFRDLSELWIEGDHYKWRAMRIAGEREDLCTGSASPK
ERFDAWARTITRMASSPMQAWCQIELKRTFGITAPLTPSSAECIWEEANSMLATENFRPRKLLARAGVEVLCTTDDPADQ
LEAHRQLVEDKEVSFRVFPTFRPDSALCLHTRQNFHDWRSRLEACSGIAIESLQTFMEALRVRYEFFHKLGCRVSDHGMD
RCYATPCSDAEATTIFSRLLLSSSDIDADDLEKWRSWFMRQIAEWNHESGWTMMLHLGARRNNNTRIFSSYGLDAGCDSI
GDFPQGESLVAFLDQLDTSERLPKTILFNSNPRDTLMFATIAGSFWGEGIRGKVQHGPPWWFLDQIYGIEDHLNAQCAVG
VLGTFVGMASDSRSFLSTARHEYFRKAITLRLADDLESGLFNPDQVDIDEFCRDLFYANAQSFFGWKVAHGNS
>Mature_472_residues
TIRRNFTASVRENALTLYERHASLPIIDYHGHLPPARLASNAHFRDLSELWIEGDHYKWRAMRIAGEREDLCTGSASPKE
RFDAWARTITRMASSPMQAWCQIELKRTFGITAPLTPSSAECIWEEANSMLATENFRPRKLLARAGVEVLCTTDDPADQL
EAHRQLVEDKEVSFRVFPTFRPDSALCLHTRQNFHDWRSRLEACSGIAIESLQTFMEALRVRYEFFHKLGCRVSDHGMDR
CYATPCSDAEATTIFSRLLLSSSDIDADDLEKWRSWFMRQIAEWNHESGWTMMLHLGARRNNNTRIFSSYGLDAGCDSIG
DFPQGESLVAFLDQLDTSERLPKTILFNSNPRDTLMFATIAGSFWGEGIRGKVQHGPPWWFLDQIYGIEDHLNAQCAVGV
LGTFVGMASDSRSFLSTARHEYFRKAITLRLADDLESGLFNPDQVDIDEFCRDLFYANAQSFFGWKVAHGNS

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=455, Percent_Identity=39.1208791208791, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53969; Mature: 53838

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRRNFTASVRENALTLYERHASLPIIDYHGHLPPARLASNAHFRDLSELWIEGDHYKW
CCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCHHHHHHHHCCCCCEEE
RAMRIAGEREDLCTGSASPKERFDAWARTITRMASSPMQAWCQIELKRTFGITAPLTPSS
EEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHEEEEHHHCCCCCCCCCCH
AECIWEEANSMLATENFRPRKLLARAGVEVLCTTDDPADQLEAHRQLVEDKEVSFRVFPT
HHHHHHHHCCCEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEC
FRPDSALCLHTRQNFHDWRSRLEACSGIAIESLQTFMEALRVRYEFFHKLGCRVSDHGMD
CCCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
RCYATPCSDAEATTIFSRLLLSSSDIDADDLEKWRSWFMRQIAEWNHESGWTMMLHLGAR
CEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
RNNNTRIFSSYGLDAGCDSIGDFPQGESLVAFLDQLDTSERLPKTILFNSNPRDTLMFAT
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCEEEECCCCCCCEEEEE
IAGSFWGEGIRGKVQHGPPWWFLDQIYGIEDHLNAQCAVGVLGTFVGMASDSRSFLSTAR
HHHHHHCCCCCCCCCCCCCEEEHHHHHCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHH
HEYFRKAITLRLADDLESGLFNPDQVDIDEFCRDLFYANAQSFFGWKVAHGNS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHCEEEECCCCC
>Mature Secondary Structure 
TIRRNFTASVRENALTLYERHASLPIIDYHGHLPPARLASNAHFRDLSELWIEGDHYKW
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCHHHHHHHHCCCCCEEE
RAMRIAGEREDLCTGSASPKERFDAWARTITRMASSPMQAWCQIELKRTFGITAPLTPSS
EEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHEEEEHHHCCCCCCCCCCH
AECIWEEANSMLATENFRPRKLLARAGVEVLCTTDDPADQLEAHRQLVEDKEVSFRVFPT
HHHHHHHHCCCEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEC
FRPDSALCLHTRQNFHDWRSRLEACSGIAIESLQTFMEALRVRYEFFHKLGCRVSDHGMD
CCCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
RCYATPCSDAEATTIFSRLLLSSSDIDADDLEKWRSWFMRQIAEWNHESGWTMMLHLGAR
CEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
RNNNTRIFSSYGLDAGCDSIGDFPQGESLVAFLDQLDTSERLPKTILFNSNPRDTLMFAT
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCEEEECCCCCCCEEEEE
IAGSFWGEGIRGKVQHGPPWWFLDQIYGIEDHLNAQCAVGVLGTFVGMASDSRSFLSTAR
HHHHHHCCCCCCCCCCCCCEEEHHHHHCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHH
HEYFRKAITLRLADDLESGLFNPDQVDIDEFCRDLFYANAQSFFGWKVAHGNS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA