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The map label for this gene is fabG [H]

Identifier: 78221671

GI number: 78221671

Start: 496574

End: 497398

Strand: Reverse

Name: fabG [H]

Synonym: Gmet_0450

Alternate gene names: 78221671

Gene position: 497398-496574 (Counterclockwise)

Preceding gene: 78221672

Following gene: 78221670

Centisome position: 12.44

GC content: 57.21

Gene sequence:

>825_bases
ATGAACATCGTCGTTCTGGGGGCAAGCGGGGTCTTGGGGCGGGCCTTCGCCCAAGCAGCAACGGCAGTAGGGGCGGCCTG
CATCGTCGCGGGGCGAAAAGATCCCGAGATCGGCCTCCCTCACCTGCCAGTGGACGTTACCGACCCGTCTTCGGTCAGCA
ACTTCTTCACCGCTCTGGGAAAACGCAACCTCCGCATCGATGTGGCCTTCAATTTTACCGGGACACACCATGCCGTGATG
AAGCTCGGGCAAGAAGATATTCCAGAGCTTTTAAACGACTGGTCGCGAGTCATAAACACAAACCTCACCGGCGCATTTCT
TCTGACAGCCGGATTCGCGCGTCTGTTTGTCAAGCAGCGCCACGGTCATCTCGTCCACTTGTGTTCCGATGCATCCAGGG
TTTCCCTGGAAGGTTCTCACGCCTATGTCGCATCAAAACATGGCCTTGAAGGTCTAGTCAAAAGTTCCGCAGCGCAACTG
GCCCGTTTTGGGGTCCGTGTCAACGGGTTGGCCCCGGGAACCGTTGAAACACCGCTCAATCGGCACTTGTTGCGGGACGA
TGTCGGGCAACTGTCACGCAGAGCTGCTTCGATACTGGCGCATACTCCCACCAAGCGGTTCGCTACGGTAGAGGGGGTCG
TGGAATCGGCCATTGCCCTATGTATCCCCCAACGGCACCTGACTGGCAACGTGATTTTCTGCGACGACGGATACGTTATA
GAAGGGCACTCGTGGCCCGACGGGACATGGGCGGCATACCAGAGCCCAGAAACGTTGACCGATCTTCTGCACTTCTATGA
CGACCCTGAATCAAACCTGGAATAA

Upstream 100 bases:

>100_bases
CCCGATCAGGTTGACATCGATGAGTTTTGCCGTGACCTTTTCTATGCTAATGCACAATCTTTCTTCGGATGGAAGGTAGC
CCATGGGAATTCTTAGTGGC

Downstream 100 bases:

>100_bases
AAGATTCCAACAGCCCAAAAGTAACCATCAGGTAAGGAATTTCCCCATGAACTCTGAAAAACGCCCCGCCATTCTCGTAG
TCAGTGCCGGCATAATGCAG

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNIVVLGASGVLGRAFAQAATAVGAACIVAGRKDPEIGLPHLPVDVTDPSSVSNFFTALGKRNLRIDVAFNFTGTHHAVM
KLGQEDIPELLNDWSRVINTNLTGAFLLTAGFARLFVKQRHGHLVHLCSDASRVSLEGSHAYVASKHGLEGLVKSSAAQL
ARFGVRVNGLAPGTVETPLNRHLLRDDVGQLSRRAASILAHTPTKRFATVEGVVESAIALCIPQRHLTGNVIFCDDGYVI
EGHSWPDGTWAAYQSPETLTDLLHFYDDPESNLE

Sequences:

>Translated_274_residues
MNIVVLGASGVLGRAFAQAATAVGAACIVAGRKDPEIGLPHLPVDVTDPSSVSNFFTALGKRNLRIDVAFNFTGTHHAVM
KLGQEDIPELLNDWSRVINTNLTGAFLLTAGFARLFVKQRHGHLVHLCSDASRVSLEGSHAYVASKHGLEGLVKSSAAQL
ARFGVRVNGLAPGTVETPLNRHLLRDDVGQLSRRAASILAHTPTKRFATVEGVVESAIALCIPQRHLTGNVIFCDDGYVI
EGHSWPDGTWAAYQSPETLTDLLHFYDDPESNLE
>Mature_274_residues
MNIVVLGASGVLGRAFAQAATAVGAACIVAGRKDPEIGLPHLPVDVTDPSSVSNFFTALGKRNLRIDVAFNFTGTHHAVM
KLGQEDIPELLNDWSRVINTNLTGAFLLTAGFARLFVKQRHGHLVHLCSDASRVSLEGSHAYVASKHGLEGLVKSSAAQL
ARFGVRVNGLAPGTVETPLNRHLLRDDVGQLSRRAASILAHTPTKRFATVEGVVESAIALCIPQRHLTGNVIFCDDGYVI
EGHSWPDGTWAAYQSPETLTDLLHFYDDPESNLE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=204, Percent_Identity=27.9411764705882, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=28.1632653061224, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15277342, Length=103, Percent_Identity=33.0097087378641, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=25.8964143426295, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=28.4552845528455, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=184, Percent_Identity=30.9782608695652, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=24.6031746031746, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=30.4123711340206, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=204, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789208, Length=229, Percent_Identity=25.764192139738, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639444, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=31.2820512820513, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29462; Mature: 29462

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVVLGASGVLGRAFAQAATAVGAACIVAGRKDPEIGLPHLPVDVTDPSSVSNFFTALG
CEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
KRNLRIDVAFNFTGTHHAVMKLGQEDIPELLNDWSRVINTNLTGAFLLTAGFARLFVKQR
CCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
HGHLVHLCSDASRVSLEGSHAYVASKHGLEGLVKSSAAQLARFGVRVNGLAPGTVETPLN
CCCEEEEECCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCHH
RHLLRDDVGQLSRRAASILAHTPTKRFATVEGVVESAIALCIPQRHLTGNVIFCDDGYVI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEE
EGHSWPDGTWAAYQSPETLTDLLHFYDDPESNLE
ECCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIVVLGASGVLGRAFAQAATAVGAACIVAGRKDPEIGLPHLPVDVTDPSSVSNFFTALG
CEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
KRNLRIDVAFNFTGTHHAVMKLGQEDIPELLNDWSRVINTNLTGAFLLTAGFARLFVKQR
CCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
HGHLVHLCSDASRVSLEGSHAYVASKHGLEGLVKSSAAQLARFGVRVNGLAPGTVETPLN
CCCEEEEECCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCHH
RHLLRDDVGQLSRRAASILAHTPTKRFATVEGVVESAIALCIPQRHLTGNVIFCDDGYVI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEE
EGHSWPDGTWAAYQSPETLTDLLHFYDDPESNLE
ECCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]