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The map label for this gene is ftsA [H]

Identifier: 78221637

GI number: 78221637

Start: 460954

End: 462189

Strand: Direct

Name: ftsA [H]

Synonym: Gmet_0416

Alternate gene names: 78221637

Gene position: 460954-462189 (Clockwise)

Preceding gene: 78221636

Following gene: 78221638

Centisome position: 11.53

GC content: 63.83

Gene sequence:

>1236_bases
ATGTCGGCACGAAGGGATAACCTGATCGTCGGGCTCGATATCGGCACAACCAAGATTTGTGCCATCGTCGGCAACGTCAC
GGAGGACGGCATCGACATCGTTGGGATCGGCAGCAGCCCGTCGCGGGGGATGCGTAAGGGTGTCGTGATCAATATTGAGA
GCACGGTCGAGTCCATCAAGAAGGCGGTCTCCGAGGCGGAACTCATGGCTGGCTGCGAGATCCGCTCCGTCTATGCGGGG
ATCGCCGGGGGCCACATCAAGGGATTCAATTCCCAGGGGGTGATCGCCATCAAGAACCGCGAGGTGACCTCCGAAGACGT
GAAGCGGGTCATCGATGCGGCCAAGGCCATCGCCATACCCATGGACCGGGAGGTGATCCACATCCTTCCCCAGGAATTCA
TCATCGATGACCAGGATGGCATCCGCGAGCCCCTCGGCATGAGCGGGGTGCGGCTCGAAGCCAAGGTCCACATCGTCACC
GGCGCCGTGGCCAGCGCCCAGAACATTGTGAAGGCGTGCAACCGGGCCGGCCTCGACGTGGCCGACATCGTCCTGGAGCA
ACTGGCCTCCTCCGAGGCGGTCCTGTCGGCCGACGAGAAGGAGCTGGGGGTGGCGCTGGTCGACATCGGCGGCGGCACCA
CCGACATCGCCATCTTCGTGGACGGCGCCATCAAGCACACCTCGGTCCTCTCCCTGGGGGGGAACCACCTGACCAACGAC
ATCGCCGTTGGGCTCCGGACCCCCATGGCCGAGGCGGAGAAGATCAAGCAGAAGTACGGCTGCTGCATGGCATCTCTCGT
GGGGAAGGAAGAAACCATCGAGGTGCCGAGCGTGGGGGGGCGCAAGCCGCGGGTTCTCTCCCGGCAGCTTCTGGCCGAGA
TCCTGGAGCCGCGGGTGGAGGAGATCTTCACCCTGGTCAACCGCGAGATCATGAAATCGGGCTTCGAGGACCTCATCGCT
TCCGGCGTGGTCATCACCGGCGGCACCACCATCCTGGAGGGAATGCCGGAACTGGCCGAGCAGGTCTTCAACCTGCCGGT
GCGTCGCGGCATGCCGCAGCAGATCGGCGGCCTCGTTGACGTGGTCAACTCGCCGGTCTACGCAACAGGGGTCGGGCTTG
TGGTCTACGGGAGCAAGAACGTCGGCATCCGTGAGTTCCCCACGGCCCAGACTGACGAGAACCTCTTCCGGCGGGTCTCC
CGGCGGATGAAGGAGTGGTTCGGAGAGTTTTTCTAG

Upstream 100 bases:

>100_bases
GGAACTAAAGACGCAGATGACGGCAGTTGAGTACATCGATTGCGACTACCAGGACAAGATCATCGTCAAAAAAGGATAAA
GCGGGGGAGGGGGAAACACT

Downstream 100 bases:

>100_bases
TAACCGGAGCGTATTGTTCGCATTCATGTATTGTTCTGTATTGCAATGACAACCAAACACATCATGAAAGGAAAAAGGGG
GTAGGGTATGTTCGAATTCG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSARRDNLIVGLDIGTTKICAIVGNVTEDGIDIVGIGSSPSRGMRKGVVINIESTVESIKKAVSEAELMAGCEIRSVYAG
IAGGHIKGFNSQGVIAIKNREVTSEDVKRVIDAAKAIAIPMDREVIHILPQEFIIDDQDGIREPLGMSGVRLEAKVHIVT
GAVASAQNIVKACNRAGLDVADIVLEQLASSEAVLSADEKELGVALVDIGGGTTDIAIFVDGAIKHTSVLSLGGNHLTND
IAVGLRTPMAEAEKIKQKYGCCMASLVGKEETIEVPSVGGRKPRVLSRQLLAEILEPRVEEIFTLVNREIMKSGFEDLIA
SGVVITGGTTILEGMPELAEQVFNLPVRRGMPQQIGGLVDVVNSPVYATGVGLVVYGSKNVGIREFPTAQTDENLFRRVS
RRMKEWFGEFF

Sequences:

>Translated_411_residues
MSARRDNLIVGLDIGTTKICAIVGNVTEDGIDIVGIGSSPSRGMRKGVVINIESTVESIKKAVSEAELMAGCEIRSVYAG
IAGGHIKGFNSQGVIAIKNREVTSEDVKRVIDAAKAIAIPMDREVIHILPQEFIIDDQDGIREPLGMSGVRLEAKVHIVT
GAVASAQNIVKACNRAGLDVADIVLEQLASSEAVLSADEKELGVALVDIGGGTTDIAIFVDGAIKHTSVLSLGGNHLTND
IAVGLRTPMAEAEKIKQKYGCCMASLVGKEETIEVPSVGGRKPRVLSRQLLAEILEPRVEEIFTLVNREIMKSGFEDLIA
SGVVITGGTTILEGMPELAEQVFNLPVRRGMPQQIGGLVDVVNSPVYATGVGLVVYGSKNVGIREFPTAQTDENLFRRVS
RRMKEWFGEFF
>Mature_410_residues
SARRDNLIVGLDIGTTKICAIVGNVTEDGIDIVGIGSSPSRGMRKGVVINIESTVESIKKAVSEAELMAGCEIRSVYAGI
AGGHIKGFNSQGVIAIKNREVTSEDVKRVIDAAKAIAIPMDREVIHILPQEFIIDDQDGIREPLGMSGVRLEAKVHIVTG
AVASAQNIVKACNRAGLDVADIVLEQLASSEAVLSADEKELGVALVDIGGGTTDIAIFVDGAIKHTSVLSLGGNHLTNDI
AVGLRTPMAEAEKIKQKYGCCMASLVGKEETIEVPSVGGRKPRVLSRQLLAEILEPRVEEIFTLVNREIMKSGFEDLIAS
GVVITGGTTILEGMPELAEQVFNLPVRRGMPQQIGGLVDVVNSPVYATGVGLVVYGSKNVGIREFPTAQTDENLFRRVSR
RMKEWFGEFF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=388, Percent_Identity=47.9381443298969, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 43900; Mature: 43769

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRDNLIVGLDIGTTKICAIVGNVTEDGIDIVGIGSSPSRGMRKGVVINIESTVESIK
CCCCCCCEEEEEECCCCEEHHEECCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHH
KAVSEAELMAGCEIRSVYAGIAGGHIKGFNSQGVIAIKNREVTSEDVKRVIDAAKAIAIP
HHHHHHHHHHCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
MDREVIHILPQEFIIDDQDGIREPLGMSGVRLEAKVHIVTGAVASAQNIVKACNRAGLDV
CCCHHHHHCCHHHEECCCHHHCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCCCH
ADIVLEQLASSEAVLSADEKELGVALVDIGGGTTDIAIFVDGAIKHTSVLSLGGNHLTND
HHHHHHHHCCCCHHHCCCCHHHCEEEEEECCCCEEEEEEEECCCCHHHEEECCCCHHCHH
IAVGLRTPMAEAEKIKQKYGCCMASLVGKEETIEVPSVGGRKPRVLSRQLLAEILEPRVE
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
EIFTLVNREIMKSGFEDLIASGVVITGGTTILEGMPELAEQVFNLPVRRGMPQQIGGLVD
HHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCHHHHHHHHCCHHHCCCCHHHHHHHH
VVNSPVYATGVGLVVYGSKNVGIREFPTAQTDENLFRRVSRRMKEWFGEFF
HHCCCEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARRDNLIVGLDIGTTKICAIVGNVTEDGIDIVGIGSSPSRGMRKGVVINIESTVESIK
CCCCCCEEEEEECCCCEEHHEECCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHH
KAVSEAELMAGCEIRSVYAGIAGGHIKGFNSQGVIAIKNREVTSEDVKRVIDAAKAIAIP
HHHHHHHHHHCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
MDREVIHILPQEFIIDDQDGIREPLGMSGVRLEAKVHIVTGAVASAQNIVKACNRAGLDV
CCCHHHHHCCHHHEECCCHHHCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCCCH
ADIVLEQLASSEAVLSADEKELGVALVDIGGGTTDIAIFVDGAIKHTSVLSLGGNHLTND
HHHHHHHHCCCCHHHCCCCHHHCEEEEEECCCCEEEEEEEECCCCHHHEEECCCCHHCHH
IAVGLRTPMAEAEKIKQKYGCCMASLVGKEETIEVPSVGGRKPRVLSRQLLAEILEPRVE
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
EIFTLVNREIMKSGFEDLIASGVVITGGTTILEGMPELAEQVFNLPVRRGMPQQIGGLVD
HHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCHHHHHHHHCCHHHCCCCHHHHHHHH
VVNSPVYATGVGLVVYGSKNVGIREFPTAQTDENLFRRVSRRMKEWFGEFF
HHCCCEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]