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The map label for this gene is ucpA [C]

Identifier: 78221582

GI number: 78221582

Start: 405318

End: 406052

Strand: Direct

Name: ucpA [C]

Synonym: Gmet_0361

Alternate gene names: 78221582

Gene position: 405318-406052 (Clockwise)

Preceding gene: 78221581

Following gene: 78221584

Centisome position: 10.14

GC content: 65.03

Gene sequence:

>735_bases
ATGGATCTCAAAGGTAAAACCGTTTTGGTTACCGGTGCCAACGGCGGCATCGGCGGCGCCCTGGTCAGGACATTGCTGGA
CAAGGGAGTTGCCAAGGTCTACGCCGCTGCCCGGAGTATCGACGCCGTGGCTGATTTGGCCCACGGTGGTGACGACAGGG
TCGTCGCGCTCCGCCTTGACGTGACCCAAGCCGCCAGCGTGGCTGGCACGGCGGAGCAGTGCCGGGACGTGGACCTGATC
ATCAACAACGCCGGCGTCAACCGCTGCACGGGGTTCATGAGCCCCACCACCCTTGAGGACGCCCGGCTGGAGATGGAGGT
CAACTACTTCGGCACCTTGGCCATGTGCCGGGCCTTCGCGCCGGTGCTGGCTTCTCGCGGCGGCGGGGCCATCGTGAACG
TCTGTTCCATCATCGGCTTGGTCAACCTCCCCGTCAACGGGACCTATTGCGCATCCAAGGCCGCGGGGCACTCCCTGTTG
CAGGGGCTCCGTGCCGAACTGGCACCCGGGGCAATCCGGGTGATCGGCGTCTATCCCGGCCCGGTGGACACGAAGATGAC
GGCGGGGCAGGAGATGCCCAAAGCGACAACGGAGCAGGTTGCCGCCGCCATTCTGGCAGGGGTGGAGAAGGGGGACGAGT
ACATCTTCCCCGATCCCATGTCGCAGCATGTCCATGCCATGCTTGAAAAGGACCCCCGTCAGGTGGAGAGGGATTTCGGG
GCCATGGCCGGCTGA

Upstream 100 bases:

>100_bases
CTACTACAAGGAAGGGATCCCGCTCAATAACGTCAGCTGGCTTCCCTGATGAAAGCATGCCGTGGAGGCATTTTCACTGC
TCACCGCGAAAGGAGTCATT

Downstream 100 bases:

>100_bases
TAATCCTGGACTATCCTCCTGAACGCATGAAAGCCGCAGTTTCGGTGAACTGCGGCTTTCATGCGTTCAAGGTTTCAGGC
TACCGGGGTTAAAACGGAAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDLKGKTVLVTGANGGIGGALVRTLLDKGVAKVYAAARSIDAVADLAHGGDDRVVALRLDVTQAASVAGTAEQCRDVDLI
INNAGVNRCTGFMSPTTLEDARLEMEVNYFGTLAMCRAFAPVLASRGGGAIVNVCSIIGLVNLPVNGTYCASKAAGHSLL
QGLRAELAPGAIRVIGVYPGPVDTKMTAGQEMPKATTEQVAAAILAGVEKGDEYIFPDPMSQHVHAMLEKDPRQVERDFG
AMAG

Sequences:

>Translated_244_residues
MDLKGKTVLVTGANGGIGGALVRTLLDKGVAKVYAAARSIDAVADLAHGGDDRVVALRLDVTQAASVAGTAEQCRDVDLI
INNAGVNRCTGFMSPTTLEDARLEMEVNYFGTLAMCRAFAPVLASRGGGAIVNVCSIIGLVNLPVNGTYCASKAAGHSLL
QGLRAELAPGAIRVIGVYPGPVDTKMTAGQEMPKATTEQVAAAILAGVEKGDEYIFPDPMSQHVHAMLEKDPRQVERDFG
AMAG
>Mature_244_residues
MDLKGKTVLVTGANGGIGGALVRTLLDKGVAKVYAAARSIDAVADLAHGGDDRVVALRLDVTQAASVAGTAEQCRDVDLI
INNAGVNRCTGFMSPTTLEDARLEMEVNYFGTLAMCRAFAPVLASRGGGAIVNVCSIIGLVNLPVNGTYCASKAAGHSLL
QGLRAELAPGAIRVIGVYPGPVDTKMTAGQEMPKATTEQVAAAILAGVEKGDEYIFPDPMSQHVHAMLEKDPRQVERDFG
AMAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=35.678391959799, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI150247226, Length=202, Percent_Identity=32.6732673267327, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=32.3232323232323, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19743808, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=35.4166666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=33.6842105263158, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157739938, Length=240, Percent_Identity=27.5, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40548397, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI214010158, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI214010156, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI22758144, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4504503, Length=249, Percent_Identity=28.9156626506024, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22507405, Length=256, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=30.2521008403361, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7657478, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=212, Percent_Identity=30.6603773584906, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=214, Percent_Identity=31.7757009345794, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=219, Percent_Identity=31.9634703196347, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=30.5555555555556, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=32.6315789473684, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=174, Percent_Identity=36.2068965517241, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17557780, Length=224, Percent_Identity=28.125, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=192, Percent_Identity=30.7291666666667, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17558996, Length=237, Percent_Identity=28.2700421940928, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=200, Percent_Identity=34, Blast_Score=95, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=32.6530612244898, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=31.2820512820513, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=36.3636363636364, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=30.5, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=194, Percent_Identity=34.020618556701, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651139, Length=202, Percent_Identity=29.7029702970297, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116007236, Length=242, Percent_Identity=28.9256198347107, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25294; Mature: 25294

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKGKTVLVTGANGGIGGALVRTLLDKGVAKVYAAARSIDAVADLAHGGDDRVVALRLD
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
VTQAASVAGTAEQCRDVDLIINNAGVNRCTGFMSPTTLEDARLEMEVNYFGTLAMCRAFA
HHHHHHHCCCHHHHCCEEEEEECCCCHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
PVLASRGGGAIVNVCSIIGLVNLPVNGTYCASKAAGHSLLQGLRAELAPGAIRVIGVYPG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PVDTKMTAGQEMPKATTEQVAAAILAGVEKGDEYIFPDPMSQHVHAMLEKDPRQVERDFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHCCHHHHHHHHC
AMAG
CCCC
>Mature Secondary Structure
MDLKGKTVLVTGANGGIGGALVRTLLDKGVAKVYAAARSIDAVADLAHGGDDRVVALRLD
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
VTQAASVAGTAEQCRDVDLIINNAGVNRCTGFMSPTTLEDARLEMEVNYFGTLAMCRAFA
HHHHHHHCCCHHHHCCEEEEEECCCCHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
PVLASRGGGAIVNVCSIIGLVNLPVNGTYCASKAAGHSLLQGLRAELAPGAIRVIGVYPG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PVDTKMTAGQEMPKATTEQVAAAILAGVEKGDEYIFPDPMSQHVHAMLEKDPRQVERDFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHCCHHHHHHHHC
AMAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA