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The map label for this gene is plsC [H]

Identifier: 78221584

GI number: 78221584

Start: 406727

End: 407431

Strand: Direct

Name: plsC [H]

Synonym: Gmet_0363

Alternate gene names: 78221584

Gene position: 406727-407431 (Clockwise)

Preceding gene: 78221582

Following gene: 78221585

Centisome position: 10.17

GC content: 66.52

Gene sequence:

>705_bases
ATGCTTAACGGTTTGATTTATCTGCTCTTTTTTGTGCCGCTCACCGCCTTTTTCAGCGTGCTTGCCATGCTCGGCGGACT
CGTCGATTCCCGGGGGGGATTGGCCCACCGGTGCGCCCTTGCCTGGAGCCGCGCCGGCCTCATACTGGCCGGGGTCCGTC
TGAGGGTGAGCGGCGCGGAGCAGGTGCCGGCAGGGGAACCGGTGATTTTCATGGGGAACCACCAGGGGAACTTCGATATC
CTCGTCCTTTCCCGGGCCGTCCCGCGCCGGTTTTCGTGGCTGGCCAAGGAGGAGCTTTTCCGCATTCCGCTGTTCGGGTC
CGCCATGCGGCGGGCCGGCTACATTCCCGTGGACCGGAGTGACGGCCGCAAGGCCCTGCGGAGCCTTGACGCCGCGGCAA
AGAGGATCAGGGCCGGGGCCAGCGTCATCGTCTTCCCCGAGGGGACCCGGACCGTCGACGGTTCGCTCCTCCCCTTCAAG
AAGGGGGGCTTCATCCTGGCGGAGCGGGCGGGAGTGCCGATCGTCCCCTTCACCATCAACGGCAGCATGCGGGTGAACCC
CCGCAATACCTGCAACCTTGTCCGCGGCGCGGAGATCTCGGTCCGGTTCGGTGCGCCGATCCCCACCTCCGGCAGCAAAG
CCCTCAAGGGGCAGCCCCTCATGGACCGGGTGCGGGACTCCATCCAGGCCGGGTTGGAACGTTAG

Upstream 100 bases:

>100_bases
GCAGTGTATAGGAATTGGGGGGATTCTGGCAAGCTATATTTGGTTTGACGAAGGATGGAAAAAGTCGTAAGGTTAACCGG
ATTTACACCCGGAGTCGTGA

Downstream 100 bases:

>100_bases
GATGCAACTTCTTTCCCTCGCACTCATCGCCATAGGGGGCGCGGCCATGGCCTGGGGACTGCCGGCGGCCCACCGGTTGG
CAAAACCGTGGGATGTTCTG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLNGLIYLLFFVPLTAFFSVLAMLGGLVDSRGGLAHRCALAWSRAGLILAGVRLRVSGAEQVPAGEPVIFMGNHQGNFDI
LVLSRAVPRRFSWLAKEELFRIPLFGSAMRRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTVDGSLLPFK
KGGFILAERAGVPIVPFTINGSMRVNPRNTCNLVRGAEISVRFGAPIPTSGSKALKGQPLMDRVRDSIQAGLER

Sequences:

>Translated_234_residues
MLNGLIYLLFFVPLTAFFSVLAMLGGLVDSRGGLAHRCALAWSRAGLILAGVRLRVSGAEQVPAGEPVIFMGNHQGNFDI
LVLSRAVPRRFSWLAKEELFRIPLFGSAMRRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTVDGSLLPFK
KGGFILAERAGVPIVPFTINGSMRVNPRNTCNLVRGAEISVRFGAPIPTSGSKALKGQPLMDRVRDSIQAGLER
>Mature_234_residues
MLNGLIYLLFFVPLTAFFSVLAMLGGLVDSRGGLAHRCALAWSRAGLILAGVRLRVSGAEQVPAGEPVIFMGNHQGNFDI
LVLSRAVPRRFSWLAKEELFRIPLFGSAMRRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTVDGSLLPFK
KGGFILAERAGVPIVPFTINGSMRVNPRNTCNLVRGAEISVRFGAPIPTSGSKALKGQPLMDRVRDSIQAGLER

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=181, Percent_Identity=35.9116022099448, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI15100175, Length=181, Percent_Identity=35.9116022099448, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI6041665, Length=181, Percent_Identity=30.3867403314917, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1789395, Length=115, Percent_Identity=34.7826086956522, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=186, Percent_Identity=29.5698924731183, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568319, Length=127, Percent_Identity=36.2204724409449, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=220, Percent_Identity=32.2727272727273, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641614, Length=227, Percent_Identity=30.8370044052863, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641612, Length=227, Percent_Identity=30.8370044052863, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281364648, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582856, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582854, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 25255; Mature: 25255

Theoretical pI: Translated: 11.85; Mature: 11.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNGLIYLLFFVPLTAFFSVLAMLGGLVDSRGGLAHRCALAWSRAGLILAGVRLRVSGAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCC
QVPAGEPVIFMGNHQGNFDILVLSRAVPRRFSWLAKEELFRIPLFGSAMRRAGYIPVDRS
CCCCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCC
DGRKALRSLDAAAKRIRAGASVIVFPEGTRTVDGSLLPFKKGGFILAERAGVPIVPFTIN
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEC
GSMRVNPRNTCNLVRGAEISVRFGAPIPTSGSKALKGQPLMDRVRDSIQAGLER
CEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNGLIYLLFFVPLTAFFSVLAMLGGLVDSRGGLAHRCALAWSRAGLILAGVRLRVSGAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCC
QVPAGEPVIFMGNHQGNFDILVLSRAVPRRFSWLAKEELFRIPLFGSAMRRAGYIPVDRS
CCCCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCC
DGRKALRSLDAAAKRIRAGASVIVFPEGTRTVDGSLLPFKKGGFILAERAGVPIVPFTIN
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEC
GSMRVNPRNTCNLVRGAEISVRFGAPIPTSGSKALKGQPLMDRVRDSIQAGLER
CEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]