Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 78221426

GI number: 78221426

Start: 235068

End: 236192

Strand: Direct

Name: yycG [H]

Synonym: Gmet_0202

Alternate gene names: 78221426

Gene position: 235068-236192 (Clockwise)

Preceding gene: 78221425

Following gene: 78221427

Centisome position: 5.88

GC content: 60.0

Gene sequence:

>1125_bases
ATGGACGTTGTGGCGAAATTCCAGGCTGAGCGGGATGTCAAGACGATCCTCGTCGTTGACGACGAGGCGGTGATCCGTGA
CCTCTGCGCCCGGGCACTCAAGGGGTACCGGGTGCTCCAGGCGGCCGACGGCGAGGAGGCGTTGCGGCTCTTCGAGAAGG
GGGGGGTCGACGTCATCCTCACCGACGTGATGATGCCGAAGATCAACGGCATCGAGCTGTTGCGCCGCCTGAAAGATCTG
GAGCCCACCATCGTGGTCATCGTCATGACCGGCTATGCCGAGAAGGAGATCATTCTCAACGCCCTCAAGGCCGATGCCGA
CGACTTCATCACCAAACCCCTGAACATCCTTCAGCTCAAGACGGCGGTGGACAAGGCCCTGGACAAGAAGGCCCTTAAGG
AGGAACTCGCCAACCTCAAGAGCATGGATCGACTCAAGAGCAACTTCCTCTCCCTCATCTCGCACAAGTTTCGCACCCCC
ATTACCGCCATCTCCCTCTTTCTCCAGAACCTGGCGAGCGGGGTTTGCGACCCGGACGACCCTGATTCGCGCGAGAACCT
GAAACTCATCTGCGGCCAGTCCAGATACCTTGAGAACCTTGTCGCCGAGCTCCTGGTATTCAGCCGCTTCTTGGCCGCCG
GGGAAGAGCTTCACCTGGAGCCGTGCAGCCTCCCTGAAATCATTCGTCCCCTGGTTGCCTCTTCCAAGGAGGCGACTGCC
AAGCCGGGCGTCGTTGCGTCCTTCGATCTGGAGCAGCTCTCCCCCCTGTCCCTCGATCGGGAGAAAATCGCCTTTGCCAT
CGGCCAGGTGATCGACAACGCCTTTAAGTTTTCCCGCGAAACGGGGACTGTCTCCTTCTCCCTGCGTGAGGACAACGTTG
CCTGCCGCCTGACCGTGGAGGATGAAGGCATCGGGATCCCGAAGGAAGAGCTGCCGAAGATCTTCGAGAAGTTCTATCAG
GTGGACCTTGAGGGCGCCGGCCAGATTCGCGGTTTCGGCCTCGGCCTTTTCTACGCACGGGAGTTTGTCAAGCTTCACGG
CGGCACCATCACCGTGGAAAGCGAGCCCGAAAAGGGAACCCGCGTTACGGTCCTTCTTCCCCTCCATTCGTCCATTACGC
CCTGA

Upstream 100 bases:

>100_bases
GGCGGGGGGGAGCCAGCCCGACATGCTGGCCGAGGCCCTCGGTAAGGTGTACGGGCTCATCGGCTGATCGGGCGGCCGGG
CAGGGAGAGGGTGGTACACC

Downstream 100 bases:

>100_bases
GTTTCCTCACACTCCGGAGGTGGGCAAACCCGCCTTTCGTATTGATTATTTCCCCCTATCTGCTATAGTTGCACCTTTCT
TGAGCCCCTTCCGGCACCAC

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDVVAKFQAERDVKTILVVDDEAVIRDLCARALKGYRVLQAADGEEALRLFEKGGVDVILTDVMMPKINGIELLRRLKDL
EPTIVVIVMTGYAEKEIILNALKADADDFITKPLNILQLKTAVDKALDKKALKEELANLKSMDRLKSNFLSLISHKFRTP
ITAISLFLQNLASGVCDPDDPDSRENLKLICGQSRYLENLVAELLVFSRFLAAGEELHLEPCSLPEIIRPLVASSKEATA
KPGVVASFDLEQLSPLSLDREKIAFAIGQVIDNAFKFSRETGTVSFSLREDNVACRLTVEDEGIGIPKEELPKIFEKFYQ
VDLEGAGQIRGFGLGLFYAREFVKLHGGTITVESEPEKGTRVTVLLPLHSSITP

Sequences:

>Translated_374_residues
MDVVAKFQAERDVKTILVVDDEAVIRDLCARALKGYRVLQAADGEEALRLFEKGGVDVILTDVMMPKINGIELLRRLKDL
EPTIVVIVMTGYAEKEIILNALKADADDFITKPLNILQLKTAVDKALDKKALKEELANLKSMDRLKSNFLSLISHKFRTP
ITAISLFLQNLASGVCDPDDPDSRENLKLICGQSRYLENLVAELLVFSRFLAAGEELHLEPCSLPEIIRPLVASSKEATA
KPGVVASFDLEQLSPLSLDREKIAFAIGQVIDNAFKFSRETGTVSFSLREDNVACRLTVEDEGIGIPKEELPKIFEKFYQ
VDLEGAGQIRGFGLGLFYAREFVKLHGGTITVESEPEKGTRVTVLLPLHSSITP
>Mature_374_residues
MDVVAKFQAERDVKTILVVDDEAVIRDLCARALKGYRVLQAADGEEALRLFEKGGVDVILTDVMMPKINGIELLRRLKDL
EPTIVVIVMTGYAEKEIILNALKADADDFITKPLNILQLKTAVDKALDKKALKEELANLKSMDRLKSNFLSLISHKFRTP
ITAISLFLQNLASGVCDPDDPDSRENLKLICGQSRYLENLVAELLVFSRFLAAGEELHLEPCSLPEIIRPLVASSKEATA
KPGVVASFDLEQLSPLSLDREKIAFAIGQVIDNAFKFSRETGTVSFSLREDNVACRLTVEDEGIGIPKEELPKIFEKFYQ
VDLEGAGQIRGFGLGLFYAREFVKLHGGTITVESEPEKGTRVTVLLPLHSSITP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=268, Percent_Identity=26.4925373134328, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=31.7991631799163, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.4900398406374, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=36.6412213740458, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=27.0742358078603, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=27.1317829457364, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=30.2521008403361, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=25, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=37.719298245614, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=25.2, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=127, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=24.3119266055046, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=104, Percent_Identity=35.5769230769231, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786599, Length=203, Percent_Identity=27.0935960591133, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789809, Length=181, Percent_Identity=28.1767955801105, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41368; Mature: 41368

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVAKFQAERDVKTILVVDDEAVIRDLCARALKGYRVLQAADGEEALRLFEKGGVDVIL
CCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEE
TDVMMPKINGIELLRRLKDLEPTIVVIVMTGYAEKEIILNALKADADDFITKPLNILQLK
ECHHCCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHCCHHHHHHH
TAVDKALDKKALKEELANLKSMDRLKSNFLSLISHKFRTPITAISLFLQNLASGVCDPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
PDSRENLKLICGQSRYLENLVAELLVFSRFLAAGEELHLEPCSLPEIIRPLVASSKEATA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCC
KPGVVASFDLEQLSPLSLDREKIAFAIGQVIDNAFKFSRETGTVSFSLREDNVACRLTVE
CCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEC
DEGIGIPKEELPKIFEKFYQVDLEGAGQIRGFGLGLFYAREFVKLHGGTITVESEPEKGT
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCC
RVTVLLPLHSSITP
EEEEEEECCCCCCC
>Mature Secondary Structure
MDVVAKFQAERDVKTILVVDDEAVIRDLCARALKGYRVLQAADGEEALRLFEKGGVDVIL
CCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEE
TDVMMPKINGIELLRRLKDLEPTIVVIVMTGYAEKEIILNALKADADDFITKPLNILQLK
ECHHCCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHCCHHHHHHH
TAVDKALDKKALKEELANLKSMDRLKSNFLSLISHKFRTPITAISLFLQNLASGVCDPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
PDSRENLKLICGQSRYLENLVAELLVFSRFLAAGEELHLEPCSLPEIIRPLVASSKEATA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCC
KPGVVASFDLEQLSPLSLDREKIAFAIGQVIDNAFKFSRETGTVSFSLREDNVACRLTVE
CCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEC
DEGIGIPKEELPKIFEKFYQVDLEGAGQIRGFGLGLFYAREFVKLHGGTITVESEPEKGT
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCC
RVTVLLPLHSSITP
EEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]