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The map label for this gene is hypD2 [H]

Identifier: 78221344

GI number: 78221344

Start: 142993

End: 144084

Strand: Reverse

Name: hypD2 [H]

Synonym: Gmet_0117

Alternate gene names: 78221344

Gene position: 144084-142993 (Counterclockwise)

Preceding gene: 78221345

Following gene: 78221343

Centisome position: 3.6

GC content: 67.95

Gene sequence:

>1092_bases
GTGAAATACCAGGACGAATTCCGCGACCGCCACGTGGTGCTGGGCCTTGCCGCCCGGATCAGGGAGCACGTGGCCGGGCG
TACGGAGCCCATGACCTTCATGGAGGTCTGCGGCACTCATACCATGTCGATCTATCAGTACGGGCTCCGCACCCTCCTCC
CTCCCCAGGTGCGGCTCATCTCCGGACCCGGCTGCCCGGTCTGCGTCACCCCCAATGAGTACCTGGACCGGGCCGTGGCC
CTCTGCCGGCTCCCCGACGTTATCGTCGCCACCTTCGGCGACATGGTCCGGGTCCCCGGCTCCACGTCGTCCCTCCAGGA
GGAGCGCGCCCGGGGGGCCGACATCCGGATCGTCTACTCCCCCTTGGACGCCGTTGCCATTGCTGCCAGGAATCCGGAGA
AGCGGGTGGTCTTTCTCGGCGTCGGCTTCGAGACCACGGCCCCGGCCATTGGCGGGAGCATCCTGGCGGCGAAGAAGCAG
GGGCTCGCCAACTACTTCGTGCTGGCAGCCCACAAGACCATGCCCAAGCCCATGGGGGTCCTCTCCGCCGACCCGGAGCT
GAAGATCGACGGCTACATCTGCCCCGCCCACGTGAGCACCATCACCGGGCCGGAGATCTACCGCTTCCTGGCCGAGGAGT
TTCATATCCCCTGCGTCATCACCGGTTTCGAGCCTGCGGACGTCATGCAGGGGGTCGAGATGCTCGTCCGCCAGGTGGTG
GCGGGGGAGAGCCGGGTGGAGACCCAGTACAGCAGGGTGGTACGGCCTGAGGGGAACCGCAAGGCCCAGGAGGTGATCCG
GGAGGTCTTCACCCCCTGCGATGCCCCCTGGCGCGGCATCGGGGTCATCCCGGGGAGCGGCCTGCGGATCGCCGACGCCT
ATGCCGTGTTTGACGCCGAGAAGGCGATTCCCGTGGCGGTGGAGGAGACCCGGGAACACGCGGGATGTCTCTGCGGCGAG
ATCCTCAAGGGGAAAGCGGCCCCAACCGACTGTCCCCTCTTTGGCGGCGCCTGCACCCCCGAGTCCCCCGTGGGGGCCTG
CATGGTCTCCTCCGAGGGGACCTGCGCGGCGGCGTACAAGTATGGGCAGTGA

Upstream 100 bases:

>100_bases
TCATCGTCCACGCGGGTTTTGCCATCTCCCGCCTCGATGAGGAGGAGGCGCAGGAGACGCTGAGGCTCATGAGAGAGGTG
TTCAAACCGGAGGACATGGC

Downstream 100 bases:

>100_bases
CCAGCAGCAAAGAATATGACCGCTCGGAGAATCCTGTGAACAAAGACCTCATCCTCCTGGGCCACGGCAGCGGCGGGAAG
CTTTCCCACCAGCTCCTGGA

Product: hydrogenase formation HypD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKYQDEFRDRHVVLGLAARIREHVAGRTEPMTFMEVCGTHTMSIYQYGLRTLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPDVIVATFGDMVRVPGSTSSLQEERARGADIRIVYSPLDAVAIAARNPEKRVVFLGVGFETTAPAIGGSILAAKKQ
GLANYFVLAAHKTMPKPMGVLSADPELKIDGYICPAHVSTITGPEIYRFLAEEFHIPCVITGFEPADVMQGVEMLVRQVV
AGESRVETQYSRVVRPEGNRKAQEVIREVFTPCDAPWRGIGVIPGSGLRIADAYAVFDAEKAIPVAVEETREHAGCLCGE
ILKGKAAPTDCPLFGGACTPESPVGACMVSSEGTCAAAYKYGQ

Sequences:

>Translated_363_residues
MKYQDEFRDRHVVLGLAARIREHVAGRTEPMTFMEVCGTHTMSIYQYGLRTLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPDVIVATFGDMVRVPGSTSSLQEERARGADIRIVYSPLDAVAIAARNPEKRVVFLGVGFETTAPAIGGSILAAKKQ
GLANYFVLAAHKTMPKPMGVLSADPELKIDGYICPAHVSTITGPEIYRFLAEEFHIPCVITGFEPADVMQGVEMLVRQVV
AGESRVETQYSRVVRPEGNRKAQEVIREVFTPCDAPWRGIGVIPGSGLRIADAYAVFDAEKAIPVAVEETREHAGCLCGE
ILKGKAAPTDCPLFGGACTPESPVGACMVSSEGTCAAAYKYGQ
>Mature_363_residues
MKYQDEFRDRHVVLGLAARIREHVAGRTEPMTFMEVCGTHTMSIYQYGLRTLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPDVIVATFGDMVRVPGSTSSLQEERARGADIRIVYSPLDAVAIAARNPEKRVVFLGVGFETTAPAIGGSILAAKKQ
GLANYFVLAAHKTMPKPMGVLSADPELKIDGYICPAHVSTITGPEIYRFLAEEFHIPCVITGFEPADVMQGVEMLVRQVV
AGESRVETQYSRVVRPEGNRKAQEVIREVFTPCDAPWRGIGVIPGSGLRIADAYAVFDAEKAIPVAVEETREHAGCLCGE
ILKGKAAPTDCPLFGGACTPESPVGACMVSSEGTCAAAYKYGQ

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=368, Percent_Identity=45.6521739130435, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39143; Mature: 39143

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQDEFRDRHVVLGLAARIREHVAGRTEPMTFMEVCGTHTMSIYQYGLRTLLPPQVRLI
CCCCHHHCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
SGPGCPVCVTPNEYLDRAVALCRLPDVIVATFGDMVRVPGSTSSLQEERARGADIRIVYS
ECCCCCEEECCHHHHHHHHHHHCCCHHHHHHCCCCEECCCCCHHHHHHHHCCCCEEEEEC
PLDAVAIAARNPEKRVVFLGVGFETTAPAIGGSILAAKKQGLANYFVLAAHKTMPKPMGV
CCCEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCC
LSADPELKIDGYICPAHVSTITGPEIYRFLAEEFHIPCVITGFEPADVMQGVEMLVRQVV
CCCCCCEEECCEECCCHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
AGESRVETQYSRVVRPEGNRKAQEVIREVFTPCDAPWRGIGVIPGSGLRIADAYAVFDAE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEHHEEEEECC
KAIPVAVEETREHAGCLCGEILKGKAAPTDCPLFGGACTPESPVGACMVSSEGTCAAAYK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEE
YGQ
CCC
>Mature Secondary Structure
MKYQDEFRDRHVVLGLAARIREHVAGRTEPMTFMEVCGTHTMSIYQYGLRTLLPPQVRLI
CCCCHHHCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
SGPGCPVCVTPNEYLDRAVALCRLPDVIVATFGDMVRVPGSTSSLQEERARGADIRIVYS
ECCCCCEEECCHHHHHHHHHHHCCCHHHHHHCCCCEECCCCCHHHHHHHHCCCCEEEEEC
PLDAVAIAARNPEKRVVFLGVGFETTAPAIGGSILAAKKQGLANYFVLAAHKTMPKPMGV
CCCEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCC
LSADPELKIDGYICPAHVSTITGPEIYRFLAEEFHIPCVITGFEPADVMQGVEMLVRQVV
CCCCCCEEECCEECCCHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
AGESRVETQYSRVVRPEGNRKAQEVIREVFTPCDAPWRGIGVIPGSGLRIADAYAVFDAE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEHHEEEEECC
KAIPVAVEETREHAGCLCGEILKGKAAPTDCPLFGGACTPESPVGACMVSSEGTCAAAYK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEE
YGQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]