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The map label for this gene is rpe [H]

Identifier: 78221294

GI number: 78221294

Start: 82324

End: 82989

Strand: Direct

Name: rpe [H]

Synonym: Gmet_0067

Alternate gene names: 78221294

Gene position: 82324-82989 (Clockwise)

Preceding gene: 78221293

Following gene: 78221295

Centisome position: 2.06

GC content: 59.91

Gene sequence:

>666_bases
ATGAAGAAGATAGCGCCATCAATTCTGTCCGCCGATTTTTCCCGGCTCGGCGACGAGGTCAGGGCCGTGGCAGCCGCCGG
GGCCGACTATATCCACGTGGACGTCATGGACGGGCACTTCGTGCCCAACATCACCATCGGTCCCCCGGTGGTGGAGGCGG
TCCGGAAGGTGACCGAACTTCCCCTCGACGTGCACCTCATGATCGAAAACCCCGACCGCTACATTCCCGATTTCGCCAAG
GCCGGCTCCGACATCATCGTCGTTCATGCCGAGGCATCGGTTCACCTCCACCGGACCATCCAGCTCATCAAGTCCCTGGG
AAAAAAGGCAGGGGTATCCCTTAACCCGGCCACCCCCCTGTCGGTCCTGGAGTATGTCCTTGACGAACTGGACCTGGTCC
TCCTCATGACCGTCAACCCCGGCTTTGGGGGACAGTCATTCATCGAGGCCTGCCTGCCGAAGATCCAGGCCCTGCGGGCC
ATGCTCGACCGGCGGGGATGCAATGCCGAACTGGAAGTGGACGGCGGCGTGAAGATCGACAACATCGACCGGATCGCCCA
TGCGGGAGCCAATGTCTTCGTGGCCGGAAGCGCCGTTTTCGGAAGCAAAGATTACAAGGAAACAATAAAAGAACTAAAGC
GCCGGGCAAAAGAGCCGATACTGTAA

Upstream 100 bases:

>100_bases
ATTTACCGGTCGGGGGCATTTCCGGAGCTGGCCCCACCGGCACGGCATGGACGGTTTTTTCGCCGCCCGGATCAGAAAGC
TCTAGCACGTGGAGGATGCA

Downstream 100 bases:

>100_bases
CTACGTGTCGTGCACGTTATTCGACAAGCGTTTAGAAATGACAGAGTTGGTTGTCAAGCAGAGTGAACTCCCGGAGCGGA
TCAGGACCGCCCTGGCAAAC

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPPVVEAVRKVTELPLDVHLMIENPDRYIPDFAK
AGSDIIVVHAEASVHLHRTIQLIKSLGKKAGVSLNPATPLSVLEYVLDELDLVLLMTVNPGFGGQSFIEACLPKIQALRA
MLDRRGCNAELEVDGGVKIDNIDRIAHAGANVFVAGSAVFGSKDYKETIKELKRRAKEPIL

Sequences:

>Translated_221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPPVVEAVRKVTELPLDVHLMIENPDRYIPDFAK
AGSDIIVVHAEASVHLHRTIQLIKSLGKKAGVSLNPATPLSVLEYVLDELDLVLLMTVNPGFGGQSFIEACLPKIQALRA
MLDRRGCNAELEVDGGVKIDNIDRIAHAGANVFVAGSAVFGSKDYKETIKELKRRAKEPIL
>Mature_221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPPVVEAVRKVTELPLDVHLMIENPDRYIPDFAK
AGSDIIVVHAEASVHLHRTIQLIKSLGKKAGVSLNPATPLSVLEYVLDELDLVLLMTVNPGFGGQSFIEACLPKIQALRA
MLDRRGCNAELEVDGGVKIDNIDRIAHAGANVFVAGSAVFGSKDYKETIKELKRRAKEPIL

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=218, Percent_Identity=41.743119266055, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI219879828, Length=218, Percent_Identity=39.9082568807339, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI24307923, Length=173, Percent_Identity=31.7919075144509, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=58.2938388625592, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1790523, Length=220, Percent_Identity=38.6363636363636, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=35.7487922705314, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=40.0900900900901, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=43.5555555555556, Blast_Score=192, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=42.9245283018868, Blast_Score=174, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23894; Mature: 23894

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPPVVEAVRKVTEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
PLDVHLMIENPDRYIPDFAKAGSDIIVVHAEASVHLHRTIQLIKSLGKKAGVSLNPATPL
CCEEEEEEECCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SVLEYVLDELDLVLLMTVNPGFGGQSFIEACLPKIQALRAMLDRRGCNAELEVDGGVKID
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEC
NIDRIAHAGANVFVAGSAVFGSKDYKETIKELKRRAKEPIL
CHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPPVVEAVRKVTEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
PLDVHLMIENPDRYIPDFAKAGSDIIVVHAEASVHLHRTIQLIKSLGKKAGVSLNPATPL
CCEEEEEEECCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SVLEYVLDELDLVLLMTVNPGFGGQSFIEACLPKIQALRAMLDRRGCNAELEVDGGVKID
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEC
NIDRIAHAGANVFVAGSAVFGSKDYKETIKELKRRAKEPIL
CHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]