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The map label for this gene is nudL [H]

Identifier: 78221295

GI number: 78221295

Start: 83027

End: 83611

Strand: Direct

Name: nudL [H]

Synonym: Gmet_0068

Alternate gene names: 78221295

Gene position: 83027-83611 (Clockwise)

Preceding gene: 78221294

Following gene: 78221296

Centisome position: 2.08

GC content: 61.88

Gene sequence:

>585_bases
ATGACAGAGTTGGTTGTCAAGCAGAGTGAACTCCCGGAGCGGATCAGGACCGCCCTGGCAAACCGGAAGCGGGTACCCAT
GGCGCCGGGGCCGGTTCCGGCCGCCATCCTCGTTCCCCTCTTCCTGGAGGGGGGTGAGTACCATATCCTCTTTACCAAGA
GGGCGGAGCACCTGAACCATCACCGGGGAGAGATTTCCTTCCCCGGCGGGGTACGCCACCCCGACGACGGGGGCCCCCGC
GAGACGGCCCTGCGGGAGACCTGGGAAGAAGTTGGCATCAGACCGGGGGATGTGGACGTGCTGGGGGAACTGGATGATTA
TTTCTCCATCCACAACTACCTGGTGACGCCGGTGGTGGGGATCTTCCCTCCCCGCTACCCGCTGGAAGTGAACCCGGACG
AAATCGAGCGGATCATCACGGTGCCGCTGACGCATCTCCTCAGGCCGGAAATCTTTCGGGTCGAGGATTGGAACTGGAAG
GGACGTACCCATCCGGTCTGTTTTTTCACGTACGAAGGGGACGAGATCTGGGGGCTGACCGCTGCCATCCTCAAGCAGTT
CCTGGATCTGACGTTCCAGCGGTAA

Upstream 100 bases:

>100_bases
AGCAAAGATTACAAGGAAACAATAAAAGAACTAAAGCGCCGGGCAAAAGAGCCGATACTGTAACTACGTGTCGTGCACGT
TATTCGACAAGCGTTTAGAA

Downstream 100 bases:

>100_bases
CGTGTGGAGCAGGAGAAATCGCGTAGCCAGGTGCTACGGGAGCATAGGGCTGAAATGAAGAAGACAGTCTTGGTTATCGA
CGACTCGGACACCCTGCGGG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTELVVKQSELPERIRTALANRKRVPMAPGPVPAAILVPLFLEGGEYHILFTKRAEHLNHHRGEISFPGGVRHPDDGGPR
ETALRETWEEVGIRPGDVDVLGELDDYFSIHNYLVTPVVGIFPPRYPLEVNPDEIERIITVPLTHLLRPEIFRVEDWNWK
GRTHPVCFFTYEGDEIWGLTAAILKQFLDLTFQR

Sequences:

>Translated_194_residues
MTELVVKQSELPERIRTALANRKRVPMAPGPVPAAILVPLFLEGGEYHILFTKRAEHLNHHRGEISFPGGVRHPDDGGPR
ETALRETWEEVGIRPGDVDVLGELDDYFSIHNYLVTPVVGIFPPRYPLEVNPDEIERIITVPLTHLLRPEIFRVEDWNWK
GRTHPVCFFTYEGDEIWGLTAAILKQFLDLTFQR
>Mature_193_residues
TELVVKQSELPERIRTALANRKRVPMAPGPVPAAILVPLFLEGGEYHILFTKRAEHLNHHRGEISFPGGVRHPDDGGPRE
TALRETWEEVGIRPGDVDVLGELDDYFSIHNYLVTPVVGIFPPRYPLEVNPDEIERIITVPLTHLLRPEIFRVEDWNWKG
RTHPVCFFTYEGDEIWGLTAAILKQFLDLTFQR

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=170, Percent_Identity=36.4705882352941, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788115, Length=154, Percent_Identity=37.012987012987, Blast_Score=85, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17536993, Length=173, Percent_Identity=31.2138728323699, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17510677, Length=125, Percent_Identity=35.2, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859683, Length=191, Percent_Identity=32.9842931937173, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22251; Mature: 22120

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELVVKQSELPERIRTALANRKRVPMAPGPVPAAILVPLFLEGGEYHILFTKRAEHLNH
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHC
HRGEISFPGGVRHPDDGGPRETALRETWEEVGIRPGDVDVLGELDDYFSIHNYLVTPVVG
CCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHH
IFPPRYPLEVNPDEIERIITVPLTHLLRPEIFRVEDWNWKGRTHPVCFFTYEGDEIWGLT
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHH
AAILKQFLDLTFQR
HHHHHHHHHHHCCC
>Mature Secondary Structure 
TELVVKQSELPERIRTALANRKRVPMAPGPVPAAILVPLFLEGGEYHILFTKRAEHLNH
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHC
HRGEISFPGGVRHPDDGGPRETALRETWEEVGIRPGDVDVLGELDDYFSIHNYLVTPVVG
CCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHH
IFPPRYPLEVNPDEIERIITVPLTHLLRPEIFRVEDWNWKGRTHPVCFFTYEGDEIWGLT
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHH
AAILKQFLDLTFQR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]