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The map label for this gene is kch [C]

Identifier: 78221290

GI number: 78221290

Start: 77504

End: 78559

Strand: Direct

Name: kch [C]

Synonym: Gmet_0063

Alternate gene names: 78221290

Gene position: 77504-78559 (Clockwise)

Preceding gene: 78221283

Following gene: 78221291

Centisome position: 1.94

GC content: 58.33

Gene sequence:

>1056_bases
ATGGACCCCGTACGCCATTTTAAAATTTCCATAGCTGTTCTGCTGCTCCTCGTCTCTGTCGGGACGGCCGGCTACATGGC
CATTGAGGGGTGGCAGTTCCTCGACGCTCTCTACATGACGGTCATCACCCTCGGCACCGTGGGTTTCAAGGAGGTCCACG
ACCTAAGCAATGCGGGGAAGATATTCACCATCGGGTTGATAATTTTCGGGGTGAGCGTTCTCGGCTACATCGTCGGCAGT
CTCGCCCAGATCATGTTCGAGGGGCAGATACAGCGGATCATCGGGAGGAAGAAGGTGGAGCGAAAGATAGAGGCCCTGCA
TGACCACTACATCATCTGCGGCTTTGGCCGGATCGGCGCCCTCATCTGCCGGGAATTCGCGGCCAAGCCGATGCCGTTTC
TGGTCATCGAGAAGCATCCGGAGGTGCACGAGAAACTGCACCATGAGGAGTACCTCCACATCCGGGGCGACGCCACCGAG
GACGAGACGCTGCTGCGGGCCGGGATCAAGCGGGCCAAGGGGCTGATCTCGGTGGTCACCTCCGATACGGAGAACGTCTA
CATAACCCTCACGGCCCGGGGGCTCAACCCCGACCTCTTTATTCTGGCCCGCTCCGGCGAGGAGGGGTCCGAACTCAAGC
TCAAGCGGGCCGGCGCCAACAAGGTGGTTTCGCCGTACGTCATCGGCGGGAGCCGGATGGCCCAGGCGATCCTTCGCCCC
AACGTGGTGGATTTCATCGAGATCGCCACGGGCCGGGAGCACCTGGATCTTCAGATGGAGGAGATTCAAATTCCCGAGAA
ATCAGCCTTTATTGGCGAGAACCTGGTAACTTCCGGATTCCGCAAGGAGACCGGCGTCATCATTGTGGGGATAAAAAAGG
CCTCGGGCAAGATGGTTTTCAACCCGAATCCCCACACCAAGATAGAAGCCCTCGACACCCTTATCGTCCTCGGCGAACCG
GTGGCTATTACAAAGCTGGAGCAACTGGTCGCCTGCGAATCGTGCGCCGATACGATCATCAAAAAACACCGAAAAGAGCA
CCCCGATCATGTCTAA

Upstream 100 bases:

>100_bases
TAACATGGCCTAAAAAAAAGAAAAAAGAGCGGTTCGTGGCCCGGTTACGCTCTTGCCAAGGAGGCTGGTCCGATAGTATC
TTGAGTGCGAAAGAGAGGCC

Downstream 100 bases:

>100_bases
TTGCGTCTATGCCCACGTCCCCTATTCGATGCTGGCGGCAAACCTGCCAGCCATTATCTCCCGGCGTATCAACCCGGAGA
TATTTTTTTCCGGCGATACC

Product: TrkA family potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK2 [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MDPVRHFKISIAVLLLLVSVGTAGYMAIEGWQFLDALYMTVITLGTVGFKEVHDLSNAGKIFTIGLIIFGVSVLGYIVGS
LAQIMFEGQIQRIIGRKKVERKIEALHDHYIICGFGRIGALICREFAAKPMPFLVIEKHPEVHEKLHHEEYLHIRGDATE
DETLLRAGIKRAKGLISVVTSDTENVYITLTARGLNPDLFILARSGEEGSELKLKRAGANKVVSPYVIGGSRMAQAILRP
NVVDFIEIATGREHLDLQMEEIQIPEKSAFIGENLVTSGFRKETGVIIVGIKKASGKMVFNPNPHTKIEALDTLIVLGEP
VAITKLEQLVACESCADTIIKKHRKEHPDHV

Sequences:

>Translated_351_residues
MDPVRHFKISIAVLLLLVSVGTAGYMAIEGWQFLDALYMTVITLGTVGFKEVHDLSNAGKIFTIGLIIFGVSVLGYIVGS
LAQIMFEGQIQRIIGRKKVERKIEALHDHYIICGFGRIGALICREFAAKPMPFLVIEKHPEVHEKLHHEEYLHIRGDATE
DETLLRAGIKRAKGLISVVTSDTENVYITLTARGLNPDLFILARSGEEGSELKLKRAGANKVVSPYVIGGSRMAQAILRP
NVVDFIEIATGREHLDLQMEEIQIPEKSAFIGENLVTSGFRKETGVIIVGIKKASGKMVFNPNPHTKIEALDTLIVLGEP
VAITKLEQLVACESCADTIIKKHRKEHPDHV
>Mature_351_residues
MDPVRHFKISIAVLLLLVSVGTAGYMAIEGWQFLDALYMTVITLGTVGFKEVHDLSNAGKIFTIGLIIFGVSVLGYIVGS
LAQIMFEGQIQRIIGRKKVERKIEALHDHYIICGFGRIGALICREFAAKPMPFLVIEKHPEVHEKLHHEEYLHIRGDATE
DETLLRAGIKRAKGLISVVTSDTENVYITLTARGLNPDLFILARSGEEGSELKLKRAGANKVVSPYVIGGSRMAQAILRP
NVVDFIEIATGREHLDLQMEEIQIPEKSAFIGENLVTSGFRKETGVIIVGIKKASGKMVFNPNPHTKIEALDTLIVLGEP
VAITKLEQLVACESCADTIIKKHRKEHPDHV

Specific function: Probable potassium channel protein [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=241, Percent_Identity=23.2365145228216, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 38743; Mature: 38743

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPVRHFKISIAVLLLLVSVGTAGYMAIEGWQFLDALYMTVITLGTVGFKEVHDLSNAGK
CCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
IFTIGLIIFGVSVLGYIVGSLAQIMFEGQIQRIIGRKKVERKIEALHDHYIICGFGRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHH
LICREFAAKPMPFLVIEKHPEVHEKLHHEEYLHIRGDATEDETLLRAGIKRAKGLISVVT
HHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEE
SDTENVYITLTARGLNPDLFILARSGEEGSELKLKRAGANKVVSPYVIGGSRMAQAILRP
CCCCCEEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHCC
NVVDFIEIATGREHLDLQMEEIQIPEKSAFIGENLVTSGFRKETGVIIVGIKKASGKMVF
CHHHHHHHCCCCHHHCEEHHHHCCCCHHHHHCCHHHHCCCCCCCCEEEEEEEECCCEEEE
NPNPHTKIEALDTLIVLGEPVAITKLEQLVACESCADTIIKKHRKEHPDHV
CCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDPVRHFKISIAVLLLLVSVGTAGYMAIEGWQFLDALYMTVITLGTVGFKEVHDLSNAGK
CCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
IFTIGLIIFGVSVLGYIVGSLAQIMFEGQIQRIIGRKKVERKIEALHDHYIICGFGRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHH
LICREFAAKPMPFLVIEKHPEVHEKLHHEEYLHIRGDATEDETLLRAGIKRAKGLISVVT
HHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEE
SDTENVYITLTARGLNPDLFILARSGEEGSELKLKRAGANKVVSPYVIGGSRMAQAILRP
CCCCCEEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHCC
NVVDFIEIATGREHLDLQMEEIQIPEKSAFIGENLVTSGFRKETGVIIVGIKKASGKMVF
CHHHHHHHCCCCHHHCEEHHHHCCCCHHHHHCCHHHHCCCCCCCCEEEEEEEECCCEEEE
NPNPHTKIEALDTLIVLGEPVAITKLEQLVACESCADTIIKKHRKEHPDHV
CCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]