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The map label for this gene is prmA

Identifier: 78189974

GI number: 78189974

Start: 2560587

End: 2561453

Strand: Reverse

Name: prmA

Synonym: Cag_2021

Alternate gene names: 78189974

Gene position: 2561453-2560587 (Counterclockwise)

Preceding gene: 78189975

Following gene: 78189972

Centisome position: 99.59

GC content: 46.37

Gene sequence:

>867_bases
ATGCCACACATCGGAAAGCAACCATACATTGAAATAGCCTTTACCATTGAGGCTGAACACCATGAAATGTGCATTGCATT
GCTTGCCAGCGAAGGTGTAGAATCCTTTTTAGAGGAAGATCAGCGCTTGCTCGCCTACGTTCCGCAAAGCGCATGGTCGG
AAGAAAAAAAGCAAGCCATTACCATTGCTCTCGATAATTGGCTGGGGCAGGTGCCGCCCATGCACGTCAACGTTATTGCC
GATAGAAATTGGAATGAAGAGTGGGAAGCAACACTTGAGCCGATTGAAATTTCTGACCGCTTGCTCATTGTGCAAAACAA
TAAGCAAATCACCCCAAAAGAGGGGCAAATGGTTATTTCCATTAACCCAAAAATGTCGTTTGGCACAGGTTACCATGCCA
CAACTCGCTTAATGCTGCGCCAAATGGAGGAGCTTGCATTGGCAGATAAGCGCATTATGGATATTGGAACGGGTACGGGC
GTGCTTGCTATTGCCGCCCGCAAAATGGGCAATCAGTATCCTATTTTTGCCTTCGATAACAATACGTGGTCGGTTGAAAA
TGCGGTTGAAAATTGTGAGGTCAATCAAACGGCAGATATTGCCATTCACTTGCTTGATGCCGAAGAGGAGTTAGTAAGCG
AATTGCGCAATGGCTACAATTTGATTTTAGCCAACATTAATAAAAATGTGCTCGACCGCATTTTGCCGGTGCTGCGCTCT
GCTGCCCCAACGGCTACGGTGCTGCTATCGGGCGTGCTAACGTATGATGAAGCGTGGTTAAAAAAGCTCTGCAAAAAGCT
TGGGTACGATATTGCGAAAACGTTGTATGAGGATGAATGGCTTTCGGCGTTATTGGTGGGAAAATGA

Upstream 100 bases:

>100_bases
TGCCTTTGGTGCTCGTTTACTTATTGCTGAATAATTATTCCCCCTCTTGAAAAAGAATATATTTGAAGAAAAAATTTCGG
AACATTTCACCCTTACCGTT

Downstream 100 bases:

>100_bases
GAGACTGCATTACCATTTTATGGGTTTCGGAATAGTTGTGCCATCAGAAAGTATAAATGGGTTAGGGAATTGATGTTTGG
CATAAGCCGCCGAACTCAGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MPHIGKQPYIEIAFTIEAEHHEMCIALLASEGVESFLEEDQRLLAYVPQSAWSEEKKQAITIALDNWLGQVPPMHVNVIA
DRNWNEEWEATLEPIEISDRLLIVQNNKQITPKEGQMVISINPKMSFGTGYHATTRLMLRQMEELALADKRIMDIGTGTG
VLAIAARKMGNQYPIFAFDNNTWSVENAVENCEVNQTADIAIHLLDAEEELVSELRNGYNLILANINKNVLDRILPVLRS
AAPTATVLLSGVLTYDEAWLKKLCKKLGYDIAKTLYEDEWLSALLVGK

Sequences:

>Translated_288_residues
MPHIGKQPYIEIAFTIEAEHHEMCIALLASEGVESFLEEDQRLLAYVPQSAWSEEKKQAITIALDNWLGQVPPMHVNVIA
DRNWNEEWEATLEPIEISDRLLIVQNNKQITPKEGQMVISINPKMSFGTGYHATTRLMLRQMEELALADKRIMDIGTGTG
VLAIAARKMGNQYPIFAFDNNTWSVENAVENCEVNQTADIAIHLLDAEEELVSELRNGYNLILANINKNVLDRILPVLRS
AAPTATVLLSGVLTYDEAWLKKLCKKLGYDIAKTLYEDEWLSALLVGK
>Mature_287_residues
PHIGKQPYIEIAFTIEAEHHEMCIALLASEGVESFLEEDQRLLAYVPQSAWSEEKKQAITIALDNWLGQVPPMHVNVIAD
RNWNEEWEATLEPIEISDRLLIVQNNKQITPKEGQMVISINPKMSFGTGYHATTRLMLRQMEELALADKRIMDIGTGTGV
LAIAARKMGNQYPIFAFDNNTWSVENAVENCEVNQTADIAIHLLDAEEELVSELRNGYNLILANINKNVLDRILPVLRSA
APTATVLLSGVLTYDEAWLKKLCKKLGYDIAKTLYEDEWLSALLVGK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=162, Percent_Identity=30.2469135802469, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32403; Mature: 32271

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIGKQPYIEIAFTIEAEHHEMCIALLASEGVESFLEEDQRLLAYVPQSAWSEEKKQAI
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHEE
TIALDNWLGQVPPMHVNVIADRNWNEEWEATLEPIEISDRLLIVQNNKQITPKEGQMVIS
EEEEECHHCCCCCEEEEEEECCCCCCCHHCCCCCEEECCEEEEEECCCEECCCCCCEEEE
INPKMSFGTGYHATTRLMLRQMEELALADKRIMDIGTGTGVLAIAARKMGNQYPIFAFDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCEEEECC
NTWSVENAVENCEVNQTADIAIHLLDAEEELVSELRNGYNLILANINKNVLDRILPVLRS
CCEEHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHC
AAPTATVLLSGVLTYDEAWLKKLCKKLGYDIAKTLYEDEWLSALLVGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHIGKQPYIEIAFTIEAEHHEMCIALLASEGVESFLEEDQRLLAYVPQSAWSEEKKQAI
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHEE
TIALDNWLGQVPPMHVNVIADRNWNEEWEATLEPIEISDRLLIVQNNKQITPKEGQMVIS
EEEEECHHCCCCCEEEEEEECCCCCCCHHCCCCCEEECCEEEEEECCCEECCCCCCEEEE
INPKMSFGTGYHATTRLMLRQMEELALADKRIMDIGTGTGVLAIAARKMGNQYPIFAFDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCEEEECC
NTWSVENAVENCEVNQTADIAIHLLDAEEELVSELRNGYNLILANINKNVLDRILPVLRS
CCEEHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHC
AAPTATVLLSGVLTYDEAWLKKLCKKLGYDIAKTLYEDEWLSALLVGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA