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The map label for this gene is aroB [H]

Identifier: 78189972

GI number: 78189972

Start: 2558847

End: 2559785

Strand: Reverse

Name: aroB [H]

Synonym: Cag_2019

Alternate gene names: 78189972

Gene position: 2559785-2558847 (Counterclockwise)

Preceding gene: 78189974

Following gene: 78189966

Centisome position: 99.52

GC content: 49.09

Gene sequence:

>939_bases
ATGACACACCGCGTAGCTTGCATAGATATTGGCACCAACACCGCCTTATTGCTTATTGCTGATCTTAATCCAACTAACGG
CACCATTCACCCCCTGTGCCATCGCCAAACCATTGTGCGACTTGGCAAAAACGTTGATGCCCATAAAGTAATTGATAGCG
CCGCTCAAACTCGCTTGATGGCTTGTATGCAGCAATATCGTCAACTTGCTGACGAGCATGGGTGTAGTTCAATTGTTGCT
GCGGGCACCAGTGCTTTGCGCGATGCCGTCAATCGTGATGAAGTGGTTCAAGCGGTAGAAAATGCAAGTGGTATTACCAT
TACTCCCATTGCAGGAGAGAGCGAAGCCGCTTTAACCTTTATGGGCGCTGTTGCAGGCGTGCAAGAGGTGCCCGAACGCT
TTGTGGTGATTGATATTGGTGGCGGCAGCACCGAAATTTCCATTGGTTCCATGCAAGGCATTGAGCACGGCATTAGCCTC
AATATTGGTTCCGTGCGTTTAACCGAGCGCTTTTTTTCATCCCTTCCCCCATCCGAAGAGGAGTTTGAAGCGGCAAAACT
CTACATCACCATGCACCTTACCACCAAGCTCTTTCCCTTTTTTGCAGGCAGAGAAGCGGTGTATGGTGTGGCTGGCACCG
TAACCACCATTGCACAAGTAACTCAAGGAATGCGCCATTTTGATGCCGAGCGGGTGCAACATTATCCACTTCAGTATCAA
GAGGTGCGCAATTTTCTTGAAAAGCTCAAAAGCAGCTCATTGGAAGAAATTATTGCGCATGGCATTCCCGATGGACGTGC
TGACGTTATTACTATGGGAACGTTGATTTTGCATCAATTTATGCGCTTGCTTGGAGCCGCCGAAGTACGCACCAGCATTC
AGGGGTTGCGCTTTGGTTTGGCGCAGCAAGAGTTGGTGAGGTTGCAAATGAAGGCATAA

Upstream 100 bases:

>100_bases
GAACCCAAGGGTTCTGCTGGGGATGATTTACTGAGTGTTATTTTACAAATACTGCAAATAAAAAGCAAACAATAATTACC
GTATTGACTTTGAATGAATT

Downstream 100 bases:

>100_bases
AAAAATGATGAGGATACATTTCGCAGAGCCTTCCTAACATAGAAATAGCAGGTAATGAGATTTTTTTGAAGAAAACGAAT
CACCTATAAATCTATTCAGT

Product: exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTHRVACIDIGTNTALLLIADLNPTNGTIHPLCHRQTIVRLGKNVDAHKVIDSAAQTRLMACMQQYRQLADEHGCSSIVA
AGTSALRDAVNRDEVVQAVENASGITITPIAGESEAALTFMGAVAGVQEVPERFVVIDIGGGSTEISIGSMQGIEHGISL
NIGSVRLTERFFSSLPPSEEEFEAAKLYITMHLTTKLFPFFAGREAVYGVAGTVTTIAQVTQGMRHFDAERVQHYPLQYQ
EVRNFLEKLKSSSLEEIIAHGIPDGRADVITMGTLILHQFMRLLGAAEVRTSIQGLRFGLAQQELVRLQMKA

Sequences:

>Translated_312_residues
MTHRVACIDIGTNTALLLIADLNPTNGTIHPLCHRQTIVRLGKNVDAHKVIDSAAQTRLMACMQQYRQLADEHGCSSIVA
AGTSALRDAVNRDEVVQAVENASGITITPIAGESEAALTFMGAVAGVQEVPERFVVIDIGGGSTEISIGSMQGIEHGISL
NIGSVRLTERFFSSLPPSEEEFEAAKLYITMHLTTKLFPFFAGREAVYGVAGTVTTIAQVTQGMRHFDAERVQHYPLQYQ
EVRNFLEKLKSSSLEEIIAHGIPDGRADVITMGTLILHQFMRLLGAAEVRTSIQGLRFGLAQQELVRLQMKA
>Mature_311_residues
THRVACIDIGTNTALLLIADLNPTNGTIHPLCHRQTIVRLGKNVDAHKVIDSAAQTRLMACMQQYRQLADEHGCSSIVAA
GTSALRDAVNRDEVVQAVENASGITITPIAGESEAALTFMGAVAGVQEVPERFVVIDIGGGSTEISIGSMQGIEHGISLN
IGSVRLTERFFSSLPPSEEEFEAAKLYITMHLTTKLFPFFAGREAVYGVAGTVTTIAQVTQGMRHFDAERVQHYPLQYQE
VRNFLEKLKSSSLEEIIAHGIPDGRADVITMGTLILHQFMRLLGAAEVRTSIQGLRFGLAQQELVRLQMKA

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=302, Percent_Identity=28.476821192053, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788848, Length=302, Percent_Identity=27.8145695364238, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33925; Mature: 33794

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRVACIDIGTNTALLLIADLNPTNGTIHPLCHRQTIVRLGKNVDAHKVIDSAAQTRLM
CCCEEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ACMQQYRQLADEHGCSSIVAAGTSALRDAVNRDEVVQAVENASGITITPIAGESEAALTF
HHHHHHHHHHHHCCCHHHHHHCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHH
MGAVAGVQEVPERFVVIDIGGGSTEISIGSMQGIEHGISLNIGSVRLTERFFSSLPPSEE
HHHHHHHHHCCCEEEEEEECCCCCEEEECCHHHHCCCCEEECCCCHHHHHHHHCCCCCHH
EFEAAKLYITMHLTTKLFPFFAGREAVYGVAGTVTTIAQVTQGMRHFDAERVQHYPLQYQ
HCCEEEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHH
EVRNFLEKLKSSSLEEIIAHGIPDGRADVITMGTLILHQFMRLLGAAEVRTSIQGLRFGL
HHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQELVRLQMKA
HHHHHHHHHCCC
>Mature Secondary Structure 
THRVACIDIGTNTALLLIADLNPTNGTIHPLCHRQTIVRLGKNVDAHKVIDSAAQTRLM
CCEEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ACMQQYRQLADEHGCSSIVAAGTSALRDAVNRDEVVQAVENASGITITPIAGESEAALTF
HHHHHHHHHHHHCCCHHHHHHCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHH
MGAVAGVQEVPERFVVIDIGGGSTEISIGSMQGIEHGISLNIGSVRLTERFFSSLPPSEE
HHHHHHHHHCCCEEEEEEECCCCCEEEECCHHHHCCCCEEECCCCHHHHHHHHCCCCCHH
EFEAAKLYITMHLTTKLFPFFAGREAVYGVAGTVTTIAQVTQGMRHFDAERVQHYPLQYQ
HCCEEEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHH
EVRNFLEKLKSSSLEEIIAHGIPDGRADVITMGTLILHQFMRLLGAAEVRTSIQGLRFGL
HHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQELVRLQMKA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]