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The map label for this gene is obgE

Identifier: 78189826

GI number: 78189826

Start: 2378864

End: 2379880

Strand: Reverse

Name: obgE

Synonym: Cag_1871

Alternate gene names: 78189826

Gene position: 2379880-2378864 (Counterclockwise)

Preceding gene: 78189828

Following gene: 78189825

Centisome position: 92.53

GC content: 48.87

Gene sequence:

>1017_bases
GTGAAGTTTGTAGATAGTGCATCGGTATTTGTGCAGGCTGGCGATGGTGGGCGTGGTTGCGTAAGCTTCCGTCGCGAAAA
ATTTGTGCCAAAAGGTGGACCTGATGGTGGCGATGGAGGGCGTGGAGGGCATGTGTGGTTAGAAACCAACAGCCATCTTA
CCACGTTGCTTGATTTTAAGTATAAGAATAAATATATCGCCGAGCGCGGTGTGCATGGGCAGGGTGCTCGTAAAACTGGC
AAAGATGGCGTTGAGGTGGTTATTCAAGTGCCGTGTGGCACCATTGTGCGCAATGCCGCAACGGGGGAAGTAATTGCCGA
TTTAACCGAAGATGCTCAAAAAATATTAATAGCACGAGGTGGACGAGGCGGACGAGGCAATCAGCATTTTGCAACGTCAA
CGCATCAAGCGCCACGCCATGCAGAGCCCGGGCAAAAAGGCGAAGAGTTTACGCTCGATTTAGAGTTAAAGCTCATGGCT
GATGTTGGCTTGGTGGGCTTTCCTAATGCAGGCAAATCAACCCTTATTTCAGTAGTAAGTGCGGCTCGTCCAAAAATTGC
CGATTACCCCTTTACCACGCTTGTGCCCAATCTTGGCATTGTGCGTTACGACGATTATAAGTCGTTTGTAATGGCAGACA
TTCCCGGTATTATTGAGGGCGCGGCTGAAGGGCGTGGGCTTGGCTTGCAATTCCTTCGCCATATTGAGCGCACCAAAGTG
CTCGCTATTCTGATTGCGGTTGATTCCCCCGATATTGAAGCTGAGTATCAAACCATTCTTGGTGAGCTTGAAAAATTTAG
TGCGACGCTTTTGCAAAAGCCACGTATTGTGGTTATTACAAAAATGGATGTAACTGACGAACCGCTTGCATTGCAACTCG
CTGGTGAGCAAACGCCAATTTTTGCTATTTCAGCCGTTGCAGGGCAGGGTTTAAAAGAGTTAAAGGATGCACTGTGGCGC
ATTATTGTTGCCGAACGTGCCGTGCCAACCAACCAAGTTCCACAAGGAGGAGAGTAA

Upstream 100 bases:

>100_bases
AAGATGTCATGGCTGTAAGATGATAAAGTGATTTATAGAGTGTGTGTAGGCGTTAAAAATAAGTAAAGAGAAAGATTTTT
TCAAATATGAGGAGTTGGTG

Downstream 100 bases:

>100_bases
GTAACATGGCAGCAGATGATGTTGTGGTACGCTATGCCCGTTTAGATGATGCACCTGTTATTGCCGCTATAACGGCAAAA
TATGCTCGTCAAGATATTAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKFVDSASVFVQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVWLETNSHLTTLLDFKYKNKYIAERGVHGQGARKTG
KDGVEVVIQVPCGTIVRNAATGEVIADLTEDAQKILIARGGRGGRGNQHFATSTHQAPRHAEPGQKGEEFTLDLELKLMA
DVGLVGFPNAGKSTLISVVSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKV
LAILIAVDSPDIEAEYQTILGELEKFSATLLQKPRIVVITKMDVTDEPLALQLAGEQTPIFAISAVAGQGLKELKDALWR
IIVAERAVPTNQVPQGGE

Sequences:

>Translated_338_residues
MKFVDSASVFVQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVWLETNSHLTTLLDFKYKNKYIAERGVHGQGARKTG
KDGVEVVIQVPCGTIVRNAATGEVIADLTEDAQKILIARGGRGGRGNQHFATSTHQAPRHAEPGQKGEEFTLDLELKLMA
DVGLVGFPNAGKSTLISVVSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKV
LAILIAVDSPDIEAEYQTILGELEKFSATLLQKPRIVVITKMDVTDEPLALQLAGEQTPIFAISAVAGQGLKELKDALWR
IIVAERAVPTNQVPQGGE
>Mature_338_residues
MKFVDSASVFVQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVWLETNSHLTTLLDFKYKNKYIAERGVHGQGARKTG
KDGVEVVIQVPCGTIVRNAATGEVIADLTEDAQKILIARGGRGGRGNQHFATSTHQAPRHAEPGQKGEEFTLDLELKLMA
DVGLVGFPNAGKSTLISVVSAARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKV
LAILIAVDSPDIEAEYQTILGELEKFSATLLQKPRIVVITKMDVTDEPLALQLAGEQTPIFAISAVAGQGLKELKDALWR
IIVAERAVPTNQVPQGGE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=314, Percent_Identity=39.8089171974522, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI111955139, Length=355, Percent_Identity=34.3661971830986, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI111955063, Length=184, Percent_Identity=38.5869565217391, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI4758796, Length=115, Percent_Identity=42.6086956521739, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4557537, Length=122, Percent_Identity=34.4262295081967, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=345, Percent_Identity=50.1449275362319, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1787454, Length=96, Percent_Identity=37.5, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=39.1975308641975, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=349, Percent_Identity=29.512893982808, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981008, Length=141, Percent_Identity=35.4609929078014, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=115, Percent_Identity=39.1304347826087, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=165, Percent_Identity=40.6060606060606, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=123, Percent_Identity=40.650406504065, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321612, Length=118, Percent_Identity=35.5932203389831, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=39.8148148148148, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24585318, Length=289, Percent_Identity=37.7162629757785, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI21356473, Length=115, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17981711, Length=124, Percent_Identity=37.9032258064516, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CHLCH (Q3APF4)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_380164.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q3APF4
- SMR:   Q3APF4
- STRING:   Q3APF4
- GeneID:   3747023
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1871
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- BioCyc:   CCHL340177:CAG_1871-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36247; Mature: 36247

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDSASVFVQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVWLETNSHLTTLLDFK
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEH
YKNKYIAERGVHGQGARKTGKDGVEVVIQVPCGTIVRNAATGEVIADLTEDAQKILIARG
HCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHEEEEEEC
GRGGRGNQHFATSTHQAPRHAEPGQKGEEFTLDLELKLMADVGLVGFPNAGKSTLISVVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHEE
LAILIAVDSPDIEAEYQTILGELEKFSATLLQKPRIVVITKMDVTDEPLALQLAGEQTPI
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCE
FAISAVAGQGLKELKDALWRIIVAERAVPTNQVPQGGE
EEEEEHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKFVDSASVFVQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHVWLETNSHLTTLLDFK
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEH
YKNKYIAERGVHGQGARKTGKDGVEVVIQVPCGTIVRNAATGEVIADLTEDAQKILIARG
HCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHEEEEEEC
GRGGRGNQHFATSTHQAPRHAEPGQKGEEFTLDLELKLMADVGLVGFPNAGKSTLISVVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVRYDDYKSFVMADIPGIIEGAAEGRGLGLQFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHEE
LAILIAVDSPDIEAEYQTILGELEKFSATLLQKPRIVVITKMDVTDEPLALQLAGEQTPI
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCE
FAISAVAGQGLKELKDALWRIIVAERAVPTNQVPQGGE
EEEEEHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA