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The map label for this gene is yugK [H]

Identifier: 78189666

GI number: 78189666

Start: 2223435

End: 2224622

Strand: Reverse

Name: yugK [H]

Synonym: Cag_1710

Alternate gene names: 78189666

Gene position: 2224622-2223435 (Counterclockwise)

Preceding gene: 78189667

Following gene: 78189665

Centisome position: 86.49

GC content: 47.9

Gene sequence:

>1188_bases
ATGAACTTTACATTCCACAATCCAACGCAACTTATTTTTGGCGCAGGTACTCTATTGCAACTTGGCGAAATTGTGCGCAC
CTATGGTAAAAAAGCTTTGCTTGTTACCGGTGGCGGTAGCGTTAAACGCAATGGCACCTTCGATCGCGCCGTTGCAAGCC
TGAATGCTGCTGGTATTGCTGTGGTTGAATGCTCTGGCGTTGAACCAAATCCTCGCCTATCATCGGTGGTAAAAGGTGCC
GAAATTGCTCGTGCCGAACAATGTGATGTGGTTATTGCTTTAGGTGGGGGAAGCACTATGGACGCAGCAAAAGTTATTGC
CGCAGCGGTTTTCTACGATGGTGATTTATGGGATATGTTCCCACATGGGCAAGCAGAACGAAGGCTCCCAACTCGTGCGT
TACCAATTATCACGGTGCCAACACTTGCAGCTACCGGTTCTGAAATGAATGGCGGCTCGGTTATTACCAATGAACAAACC
ACCGTAAAGTCATTTGTTATTGGAAAATGCCTTTACCCGCAAGTAGCTCTGGTTGATCCTGAACTGACGGTAACGGTACC
AAAAGATCAAACCGCTTATGGCATTTGTGATCTCATCACCCATGTAACCGAATCGTACTTTAACGGTGTTGATGGCACTC
CGTTGCAAGATCGTTTTGCTGAGGGTGTTATTCTTACCGCTATGGAATGGGGAGCAAAAGCCATTGCAAATGGGCACGAT
CTCGAAGCTCGGGCGCAAGTACAATGGGCATCGGTTGTGGCGCTTAACGGATGGGTGCAAGTTGGCACGTTTGGCGCTTT
TCCTGTACACATGATTGAGCACACGCTTTCGGCTCATCACGATATTGCACATGGTGCAGGGCTTGCAATTGTTAATCCCG
CATGGATGCGCTTTGCTGCTCAATCACGTCCCACAAAATTTGTACAGTTTGCCGAGCGCGTTTTTGGTTTGTCGTCTAAA
GATGCTGACGATATTGATGTTACTATGGAAGGAATCGAGCGTTTTGAGCACTTTTTACGCTCTCTTGGTTGCCCAACTCG
ATTGTCGGAAGTAGGTATTGGTGATGAGCTGCTTGCACGCTATGCAGAAGATACGTTGCTTGTTGCCCATGACGATCAAG
GTCGTCTTCCAGCACGTCCATCCATGAGCAACGCTGATATTATCGAAGTGCTCCGTTCAGCATTGTAA

Upstream 100 bases:

>100_bases
CAAGGCATAGTCTGCTCTTAAAAAGCCTATCGCATCTTATTCTGCTAATAACACCCTTCCTCCTCTTCTTAAAACTACGT
TTTTTTAATAAGCATTGAAC

Downstream 100 bases:

>100_bases
TAGCTCAGGCGGAACAATAGACTTTGCACGATGTAGAGTAAAAAGGTAGAAGGGCTTACTGAACCATTACAACCTCAGTA
AGCCCCTCTGTGTAAGGAAA

Product: NADH-dependent butanol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNFTFHNPTQLIFGAGTLLQLGEIVRTYGKKALLVTGGGSVKRNGTFDRAVASLNAAGIAVVECSGVEPNPRLSSVVKGA
EIARAEQCDVVIALGGGSTMDAAKVIAAAVFYDGDLWDMFPHGQAERRLPTRALPIITVPTLAATGSEMNGGSVITNEQT
TVKSFVIGKCLYPQVALVDPELTVTVPKDQTAYGICDLITHVTESYFNGVDGTPLQDRFAEGVILTAMEWGAKAIANGHD
LEARAQVQWASVVALNGWVQVGTFGAFPVHMIEHTLSAHHDIAHGAGLAIVNPAWMRFAAQSRPTKFVQFAERVFGLSSK
DADDIDVTMEGIERFEHFLRSLGCPTRLSEVGIGDELLARYAEDTLLVAHDDQGRLPARPSMSNADIIEVLRSAL

Sequences:

>Translated_395_residues
MNFTFHNPTQLIFGAGTLLQLGEIVRTYGKKALLVTGGGSVKRNGTFDRAVASLNAAGIAVVECSGVEPNPRLSSVVKGA
EIARAEQCDVVIALGGGSTMDAAKVIAAAVFYDGDLWDMFPHGQAERRLPTRALPIITVPTLAATGSEMNGGSVITNEQT
TVKSFVIGKCLYPQVALVDPELTVTVPKDQTAYGICDLITHVTESYFNGVDGTPLQDRFAEGVILTAMEWGAKAIANGHD
LEARAQVQWASVVALNGWVQVGTFGAFPVHMIEHTLSAHHDIAHGAGLAIVNPAWMRFAAQSRPTKFVQFAERVFGLSSK
DADDIDVTMEGIERFEHFLRSLGCPTRLSEVGIGDELLARYAEDTLLVAHDDQGRLPARPSMSNADIIEVLRSAL
>Mature_395_residues
MNFTFHNPTQLIFGAGTLLQLGEIVRTYGKKALLVTGGGSVKRNGTFDRAVASLNAAGIAVVECSGVEPNPRLSSVVKGA
EIARAEQCDVVIALGGGSTMDAAKVIAAAVFYDGDLWDMFPHGQAERRLPTRALPIITVPTLAATGSEMNGGSVITNEQT
TVKSFVIGKCLYPQVALVDPELTVTVPKDQTAYGICDLITHVTESYFNGVDGTPLQDRFAEGVILTAMEWGAKAIANGHD
LEARAQVQWASVVALNGWVQVGTFGAFPVHMIEHTLSAHHDIAHGAGLAIVNPAWMRFAAQSRPTKFVQFAERVFGLSSK
DADDIDVTMEGIERFEHFLRSLGCPTRLSEVGIGDELLARYAEDTLLVAHDDQGRLPARPSMSNADIIEVLRSAL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=381, Percent_Identity=25.1968503937008, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789386, Length=355, Percent_Identity=36.3380281690141, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082107, Length=350, Percent_Identity=30.8571428571429, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787493, Length=434, Percent_Identity=30.4147465437788, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI48994951, Length=363, Percent_Identity=25.8953168044077, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789163, Length=388, Percent_Identity=27.319587628866, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=384, Percent_Identity=24.21875, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=370, Percent_Identity=27.5675675675676, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24657991, Length=407, Percent_Identity=25.5528255528256, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42284; Mature: 42284

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFTFHNPTQLIFGAGTLLQLGEIVRTYGKKALLVTGGGSVKRNGTFDRAVASLNAAGIA
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHCCCCCEE
VVECSGVEPNPRLSSVVKGAEIARAEQCDVVIALGGGSTMDAAKVIAAAVFYDGDLWDMF
EEEECCCCCCCHHHHHHCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PHGQAERRLPTRALPIITVPTLAATGSEMNGGSVITNEQTTVKSFVIGKCLYPQVALVDP
CCCCHHHCCCCCCCCEEEECCCEECCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEECC
ELTVTVPKDQTAYGICDLITHVTESYFNGVDGTPLQDRFAEGVILTAMEWGAKAIANGHD
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEHHHCHHHHCCCCC
LEARAQVQWASVVALNGWVQVGTFGAFPVHMIEHTLSAHHDIAHGAGLAIVNPAWMRFAA
CCHHHEEEEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
QSRPTKFVQFAERVFGLSSKDADDIDVTMEGIERFEHFLRSLGCPTRLSEVGIGDELLAR
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
YAEDTLLVAHDDQGRLPARPSMSNADIIEVLRSAL
HCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNFTFHNPTQLIFGAGTLLQLGEIVRTYGKKALLVTGGGSVKRNGTFDRAVASLNAAGIA
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHCCCCCEE
VVECSGVEPNPRLSSVVKGAEIARAEQCDVVIALGGGSTMDAAKVIAAAVFYDGDLWDMF
EEEECCCCCCCHHHHHHCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PHGQAERRLPTRALPIITVPTLAATGSEMNGGSVITNEQTTVKSFVIGKCLYPQVALVDP
CCCCHHHCCCCCCCCEEEECCCEECCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEECC
ELTVTVPKDQTAYGICDLITHVTESYFNGVDGTPLQDRFAEGVILTAMEWGAKAIANGHD
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEHHHCHHHHCCCCC
LEARAQVQWASVVALNGWVQVGTFGAFPVHMIEHTLSAHHDIAHGAGLAIVNPAWMRFAA
CCHHHEEEEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
QSRPTKFVQFAERVFGLSSKDADDIDVTMEGIERFEHFLRSLGCPTRLSEVGIGDELLAR
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
YAEDTLLVAHDDQGRLPARPSMSNADIIEVLRSAL
HCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]