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The map label for this gene is cdsA [H]

Identifier: 78189431

GI number: 78189431

Start: 1935951

End: 1936775

Strand: Reverse

Name: cdsA [H]

Synonym: Cag_1470

Alternate gene names: 78189431

Gene position: 1936775-1935951 (Counterclockwise)

Preceding gene: 78189432

Following gene: 78189430

Centisome position: 75.3

GC content: 45.33

Gene sequence:

>825_bases
ATGACAAAGCTTTTACCAAACAATCTTATCCAGAGAATTGCGGTTGCCGTTGTTGGCATTCCGCTTTTGCTATGGCTTGT
GGTTGAAGGCGGTTTTTGGTTTTTTGGCTTTGTACTACTTTTATCGCTTTTAGCGGTTTCGGAATTTCACCATTTGGCAG
CTCGTAAAGCCCATCCACCAGCATTATGGGTTATGCTGCTTGTTACGGCGCTGTGGCAAACTAATGGCTATTTCCATCTT
ATTGAAGTGTGGGAATTGCTGCTTGCAGCCTTGCTCTTTTTAATGGTGATAGCCCTCTTTTTGCGCAATGGTTCACCGTT
GCTGAACATTGGCTCCATGCTTCCCGGATTGCTTTACGTGAATCTTTCGTTTGGCGCTTTGTTGCGTTTGCGGCTTGCAG
CACCAGAAGAGCGAGGGGTTACCATCCTGCTCTTGCTTTTTATTTGCGTGTGGGCAGCCGATATTTTTGCCTATTTCGGT
GGCAGTGCGTTGGGGGGAAAATTTATTCACCGCAAATTATTTGAGCGCCACAGTCCTCATAAAACATGGGAAGGCTTTGT
GCTTGGGTTATTTGGAAGTGTTGGGGCTGCTTACCTTGCCGCACTTTTTTTGCCAAATCTACCACTTCTCTTTACGTTGT
TAACGGGGGTGTTGATTGGGGTTGCAAGCCCAATAGGCGATTTAGTGGAATCCATGTTTAAGCGCGATGCAGGTGTAAAG
GATTCTTCCACGCTTATTCCCGGTCATGGGGGAGTGCTCGATCGGTTTGATACAATTATGTTTGTGGCACCAATCTTATA
CTTTCTGACTTTTTATTATTTGTAA

Upstream 100 bases:

>100_bases
AGGTTGCACACTGCTTTTTTGGCGCCTTATGCGTTGGCTTACCGACCGTATCGTTCGCCATTAATTCCATTTTTTTAGAA
TTAATTTTTTAGATGAAAAA

Downstream 100 bases:

>100_bases
TGGGTCTGTAGGTACTATCTCAGTTTCACTAAAAATTTCAATGCTCTTTGAAGTACCAAGATATAAAAAGATAGTATGAT
GGAACAAGATACCAATCAAT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTKLLPNNLIQRIAVAVVGIPLLLWLVVEGGFWFFGFVLLLSLLAVSEFHHLAARKAHPPALWVMLLVTALWQTNGYFHL
IEVWELLLAALLFLMVIALFLRNGSPLLNIGSMLPGLLYVNLSFGALLRLRLAAPEERGVTILLLLFICVWAADIFAYFG
GSALGGKFIHRKLFERHSPHKTWEGFVLGLFGSVGAAYLAALFLPNLPLLFTLLTGVLIGVASPIGDLVESMFKRDAGVK
DSSTLIPGHGGVLDRFDTIMFVAPILYFLTFYYL

Sequences:

>Translated_274_residues
MTKLLPNNLIQRIAVAVVGIPLLLWLVVEGGFWFFGFVLLLSLLAVSEFHHLAARKAHPPALWVMLLVTALWQTNGYFHL
IEVWELLLAALLFLMVIALFLRNGSPLLNIGSMLPGLLYVNLSFGALLRLRLAAPEERGVTILLLLFICVWAADIFAYFG
GSALGGKFIHRKLFERHSPHKTWEGFVLGLFGSVGAAYLAALFLPNLPLLFTLLTGVLIGVASPIGDLVESMFKRDAGVK
DSSTLIPGHGGVLDRFDTIMFVAPILYFLTFYYL
>Mature_273_residues
TKLLPNNLIQRIAVAVVGIPLLLWLVVEGGFWFFGFVLLLSLLAVSEFHHLAARKAHPPALWVMLLVTALWQTNGYFHLI
EVWELLLAALLFLMVIALFLRNGSPLLNIGSMLPGLLYVNLSFGALLRLRLAAPEERGVTILLLLFICVWAADIFAYFGG
SALGGKFIHRKLFERHSPHKTWEGFVLGLFGSVGAAYLAALFLPNLPLLFTLLTGVLIGVASPIGDLVESMFKRDAGVKD
SSTLIPGHGGVLDRFDTIMFVAPILYFLTFYYL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=223, Percent_Identity=34.9775784753363, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787677, Length=121, Percent_Identity=41.3223140495868, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30280; Mature: 30149

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKLLPNNLIQRIAVAVVGIPLLLWLVVEGGFWFFGFVLLLSLLAVSEFHHLAARKAHPP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ALWVMLLVTALWQTNGYFHLIEVWELLLAALLFLMVIALFLRNGSPLLNIGSMLPGLLYV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
NLSFGALLRLRLAAPEERGVTILLLLFICVWAADIFAYFGGSALGGKFIHRKLFERHSPH
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
KTWEGFVLGLFGSVGAAYLAALFLPNLPLLFTLLTGVLIGVASPIGDLVESMFKRDAGVK
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DSSTLIPGHGGVLDRFDTIMFVAPILYFLTFYYL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]