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The map label for this gene is trpB-1 [H]

Identifier: 78189262

GI number: 78189262

Start: 1761182

End: 1762381

Strand: Reverse

Name: trpB-1 [H]

Synonym: Cag_1297

Alternate gene names: 78189262

Gene position: 1762381-1761182 (Counterclockwise)

Preceding gene: 78189264

Following gene: 78189260

Centisome position: 68.52

GC content: 48.75

Gene sequence:

>1200_bases
ATGGAGCCCTCTCTTTACTCTGCACCCGATGCTGCTGGACACTACGGCTATTTTGGCGGCAAATTTATTCCAGAAACGCT
TATTAAAAATGCGGCTGATTTAGAGGCTGAATATTTACGAGCCAAGCAAGACCCCGCTTTTCAGCAAGAGTTAACGCTGT
TGCTGCGCGACTATGTTGGTCGTCCTACGCCGCTCTACCATGCAACGCGTTTAAGCCAACAAGTGCAAGGAGCGCAAATT
TATTTAAAGCGCGAAGATTTGTGCCATACAGGTGCGCATAAAATTAATAATGCCCTTGGTCAAGTGCTGCTTGCTCGACG
CATGGGCAAAAAGCGCGTTATTGCTGAAACAGGTGCAGGGCAGCATGGGGTTGCAACGGCAACGGTGTGTGCGCTTTTTA
ATTTAGAATGCGTGGTTTATATGGGCGAAGAGGATATTTGCCGTCAAGCGCCAAATGTTGCACGCATGAAGCTCTTGGGT
GCTGAAGTGCGAGCCGTAAGCAGTGGTTCGCGAACGCTTAAAGATGCCACCAGCGAAGCAATTCGCGATTGGATGAATAA
TCCCGAAGAGACCTTTTACATTATTGGATCAGTGGTTGGAATGCACCCCTACCCCATGATTGTGAGAGATTTTCAATCAG
TAATTGGGAAGGAAACTCGGCAGCAAATTATTGCACAAGCGGGTCGTCTGCCGGATGTTATTACCGCTTGTGTTGGTGGT
GGCAGCAATGCCATTGGTATGTTTTATGAATTTTTAAAGGATGCCGCAATGGTTGAATTGGTGGGGGTTGAAGCTGCGGG
CGAAGGGCTTACAGGGCGCCATGCCGCATCACTAACGCTTGGAACGCCCGGCGTATTGCATGGAGCCTTAACGCGCCTTC
TCCAAAACAATGACGGGCAAGTGCTTGAAGCACACTCCATTTCAGCGGGGTTAGATTACCCGGGTGTTGGGCCTGAACAT
TGCTATTTGCAAGAGCTTGGCTTGGTTTCTTACACCTCCGTTACCGACACCGAAGCGCTTGAAGCCTTAGCCACGCTTGC
TAAAACGGAAGGCATTATTTGTGCCTTAGAGTCAGCTCATGCAATTCATTATGCCATCAAACGAGCAAAGCAAATGGCGC
ACGATGGAATTTTAATTGTCAACCTGTCGGGCAGGGGCGATAAAGATATGGAGACCATTATTCGCGAATTGGGGTTGTAA

Upstream 100 bases:

>100_bases
TTTTGCTTGTAAGCGTGGCTTTCCGCAAGGATTGGAAGTTTTTCTCTCCTCAAACTTTGGCGAGCAAGCCACGCTCTAAT
GTTTAATTCATTGTACTTTC

Downstream 100 bases:

>100_bases
GTGGTTTTTTAAAAAGCTCTTAAGTTGAGAGTAATGTGATCAATGAAGTGGTGATTTGCATCGGATTACCGCAGGGAGCT
TCTCAAGGCGCACCAGATTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MEPSLYSAPDAAGHYGYFGGKFIPETLIKNAADLEAEYLRAKQDPAFQQELTLLLRDYVGRPTPLYHATRLSQQVQGAQI
YLKREDLCHTGAHKINNALGQVLLARRMGKKRVIAETGAGQHGVATATVCALFNLECVVYMGEEDICRQAPNVARMKLLG
AEVRAVSSGSRTLKDATSEAIRDWMNNPEETFYIIGSVVGMHPYPMIVRDFQSVIGKETRQQIIAQAGRLPDVITACVGG
GSNAIGMFYEFLKDAAMVELVGVEAAGEGLTGRHAASLTLGTPGVLHGALTRLLQNNDGQVLEAHSISAGLDYPGVGPEH
CYLQELGLVSYTSVTDTEALEALATLAKTEGIICALESAHAIHYAIKRAKQMAHDGILIVNLSGRGDKDMETIIRELGL

Sequences:

>Translated_399_residues
MEPSLYSAPDAAGHYGYFGGKFIPETLIKNAADLEAEYLRAKQDPAFQQELTLLLRDYVGRPTPLYHATRLSQQVQGAQI
YLKREDLCHTGAHKINNALGQVLLARRMGKKRVIAETGAGQHGVATATVCALFNLECVVYMGEEDICRQAPNVARMKLLG
AEVRAVSSGSRTLKDATSEAIRDWMNNPEETFYIIGSVVGMHPYPMIVRDFQSVIGKETRQQIIAQAGRLPDVITACVGG
GSNAIGMFYEFLKDAAMVELVGVEAAGEGLTGRHAASLTLGTPGVLHGALTRLLQNNDGQVLEAHSISAGLDYPGVGPEH
CYLQELGLVSYTSVTDTEALEALATLAKTEGIICALESAHAIHYAIKRAKQMAHDGILIVNLSGRGDKDMETIIRELGL
>Mature_399_residues
MEPSLYSAPDAAGHYGYFGGKFIPETLIKNAADLEAEYLRAKQDPAFQQELTLLLRDYVGRPTPLYHATRLSQQVQGAQI
YLKREDLCHTGAHKINNALGQVLLARRMGKKRVIAETGAGQHGVATATVCALFNLECVVYMGEEDICRQAPNVARMKLLG
AEVRAVSSGSRTLKDATSEAIRDWMNNPEETFYIIGSVVGMHPYPMIVRDFQSVIGKETRQQIIAQAGRLPDVITACVGG
GSNAIGMFYEFLKDAAMVELVGVEAAGEGLTGRHAASLTLGTPGVLHGALTRLLQNNDGQVLEAHSISAGLDYPGVGPEH
CYLQELGLVSYTSVTDTEALEALATLAKTEGIICALESAHAIHYAIKRAKQMAHDGILIVNLSGRGDKDMETIIRELGL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=52.0942408376963, Blast_Score=400, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321412, Length=381, Percent_Identity=55.9055118110236, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43061; Mature: 43061

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPSLYSAPDAAGHYGYFGGKFIPETLIKNAADLEAEYLRAKQDPAFQQELTLLLRDYVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
RPTPLYHATRLSQQVQGAQIYLKREDLCHTGAHKINNALGQVLLARRMGKKRVIAETGAG
CCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QHGVATATVCALFNLECVVYMGEEDICRQAPNVARMKLLGAEVRAVSSGSRTLKDATSEA
CCCHHHHHHHHHHCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IRDWMNNPEETFYIIGSVVGMHPYPMIVRDFQSVIGKETRQQIIAQAGRLPDVITACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGMFYEFLKDAAMVELVGVEAAGEGLTGRHAASLTLGTPGVLHGALTRLLQNNDGQ
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
VLEAHSISAGLDYPGVGPEHCYLQELGLVSYTSVTDTEALEALATLAKTEGIICALESAH
EEEECCCCCCCCCCCCCCCHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEHHHH
AIHYAIKRAKQMAHDGILIVNLSGRGDKDMETIIRELGL
HHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEPSLYSAPDAAGHYGYFGGKFIPETLIKNAADLEAEYLRAKQDPAFQQELTLLLRDYVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
RPTPLYHATRLSQQVQGAQIYLKREDLCHTGAHKINNALGQVLLARRMGKKRVIAETGAG
CCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QHGVATATVCALFNLECVVYMGEEDICRQAPNVARMKLLGAEVRAVSSGSRTLKDATSEA
CCCHHHHHHHHHHCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IRDWMNNPEETFYIIGSVVGMHPYPMIVRDFQSVIGKETRQQIIAQAGRLPDVITACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGMFYEFLKDAAMVELVGVEAAGEGLTGRHAASLTLGTPGVLHGALTRLLQNNDGQ
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
VLEAHSISAGLDYPGVGPEHCYLQELGLVSYTSVTDTEALEALATLAKTEGIICALESAH
EEEECCCCCCCCCCCCCCCHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEHHHH
AIHYAIKRAKQMAHDGILIVNLSGRGDKDMETIIRELGL
HHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]