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The map label for this gene is acoC [H]

Identifier: 78189264

GI number: 78189264

Start: 1765147

End: 1766013

Strand: Reverse

Name: acoC [H]

Synonym: Cag_1299

Alternate gene names: 78189264

Gene position: 1766013-1765147 (Counterclockwise)

Preceding gene: 78189269

Following gene: 78189262

Centisome position: 68.66

GC content: 43.71

Gene sequence:

>867_bases
ATGGCAAAAGATCATTACTTCACATGGCAGCTCTCTGCGGAGATTTCAGCAAAAATTCGTTATCAAGAGTATGGGCATGA
GCATCACGGCAAAACACCGATTCTTTTTTTGCATGGTTATGGCGCTATGCTGGAGCATTGGGATTTAAACATTCCGCATT
TTGCTGAGCAGCACAAAATGTATGCCATGGATCTTATTGGCTTTGGAAAATCGCAAAAGCCAAACGTGCGTTATTCGCTT
GAACTCTTTGCTCAGCAAATACAAACATTCCTGTTGTATAAAAAATTAGAATCAGTCATTATTGTTGGGCACTCTATGGG
AGCTGCCAGCTCGCTTTATTTTGCTCACCACCAACCAGAACCAATTAAAGCGCTGGTTATGGCTAATCCATCGGGTTTAT
TTGCTGATACTATGGATGGTGTTGCCAGCATGTTTTTTGGCTTAGTAGCTTCGCCCGTTATTGGCGATGTGCTGTTTACC
GCATTTGCTAATCCTATGGGGGTAAGCCAAAGTTTAACACCTACGTATTACAATCAAAATAAAGTTGACGATAAGCTTAT
TCGCCAATTTACGCAGCCTTTGCACGATGTGGGTGCGCAATATTCCTACATGTCGCCCTCAAAACGTCCGCTTGATTTCC
GCCTCGACCATTTACCCAAGCCCTGCAATTATCAAGGTCCGGCGTACCTTGTGTGGGGTGCTGACGATATGGCTCTGCCC
CCTCAAAAAATTATTCCCGAATTTCAGCAACTGATTCCTCATGCAGGCGCATTTATTATTCCTAAAGCGGCGCATTGCAT
TCATCACGATGCTCATGAGGCGTTTAACCAGCGTTTAGCATTTATTTTACAGGAACTTGAAGGTTAG

Upstream 100 bases:

>100_bases
TTCGCACGAAACTAATATCGGTGATTTTCTAATTGTGCTGTAACGGGTATATTCAATAATAAGTTTATCAAGGGCATTTC
TAAAGTTATTATCTACACGA

Downstream 100 bases:

>100_bases
AAAGCAGGGAAATTTTTTAGCCCAACGCTTAGTGCGTATCCCTTAAATTCTCCTGACGGTACCCACTGCATACCGATCTG
CCAGCAATGTAAGTCGTGGT

Product: dihydrolipoamide acetyltransferase

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAKDHYFTWQLSAEISAKIRYQEYGHEHHGKTPILFLHGYGAMLEHWDLNIPHFAEQHKMYAMDLIGFGKSQKPNVRYSL
ELFAQQIQTFLLYKKLESVIIVGHSMGAASSLYFAHHQPEPIKALVMANPSGLFADTMDGVASMFFGLVASPVIGDVLFT
AFANPMGVSQSLTPTYYNQNKVDDKLIRQFTQPLHDVGAQYSYMSPSKRPLDFRLDHLPKPCNYQGPAYLVWGADDMALP
PQKIIPEFQQLIPHAGAFIIPKAAHCIHHDAHEAFNQRLAFILQELEG

Sequences:

>Translated_288_residues
MAKDHYFTWQLSAEISAKIRYQEYGHEHHGKTPILFLHGYGAMLEHWDLNIPHFAEQHKMYAMDLIGFGKSQKPNVRYSL
ELFAQQIQTFLLYKKLESVIIVGHSMGAASSLYFAHHQPEPIKALVMANPSGLFADTMDGVASMFFGLVASPVIGDVLFT
AFANPMGVSQSLTPTYYNQNKVDDKLIRQFTQPLHDVGAQYSYMSPSKRPLDFRLDHLPKPCNYQGPAYLVWGADDMALP
PQKIIPEFQQLIPHAGAFIIPKAAHCIHHDAHEAFNQRLAFILQELEG
>Mature_287_residues
AKDHYFTWQLSAEISAKIRYQEYGHEHHGKTPILFLHGYGAMLEHWDLNIPHFAEQHKMYAMDLIGFGKSQKPNVRYSLE
LFAQQIQTFLLYKKLESVIIVGHSMGAASSLYFAHHQPEPIKALVMANPSGLFADTMDGVASMFFGLVASPVIGDVLFTA
FANPMGVSQSLTPTYYNQNKVDDKLIRQFTQPLHDVGAQYSYMSPSKRPLDFRLDHLPKPCNYQGPAYLVWGADDMALPP
QKIIPEFQQLIPHAGAFIIPKAAHCIHHDAHEAFNQRLAFILQELEG

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Drosophila melanogaster, GI24586385, Length=106, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586387, Length=106, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586391, Length=106, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586389, Length=106, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 32553; Mature: 32422

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDHYFTWQLSAEISAKIRYQEYGHEHHGKTPILFLHGYGAMLEHWDLNIPHFAEQHKM
CCCCCEEEEEEECEEEEEEEHHHCCHHHCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHH
YAMDLIGFGKSQKPNVRYSLELFAQQIQTFLLYKKLESVIIVGHSMGAASSLYFAHHQPE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHEEEECCCCC
PIKALVMANPSGLFADTMDGVASMFFGLVASPVIGDVLFTAFANPMGVSQSLTPTYYNQN
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KVDDKLIRQFTQPLHDVGAQYSYMSPSKRPLDFRLDHLPKPCNYQGPAYLVWGADDMALP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHCCCCCCCCCCCEEEEECCCCCCCC
PQKIIPEFQQLIPHAGAFIIPKAAHCIHHDAHEAFNQRLAFILQELEG
HHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKDHYFTWQLSAEISAKIRYQEYGHEHHGKTPILFLHGYGAMLEHWDLNIPHFAEQHKM
CCCCEEEEEEECEEEEEEEHHHCCHHHCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHH
YAMDLIGFGKSQKPNVRYSLELFAQQIQTFLLYKKLESVIIVGHSMGAASSLYFAHHQPE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHEEEECCCCC
PIKALVMANPSGLFADTMDGVASMFFGLVASPVIGDVLFTAFANPMGVSQSLTPTYYNQN
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KVDDKLIRQFTQPLHDVGAQYSYMSPSKRPLDFRLDHLPKPCNYQGPAYLVWGADDMALP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHCCCCCCCCCCCEEEEECCCCCCCC
PQKIIPEFQQLIPHAGAFIIPKAAHCIHHDAHEAFNQRLAFILQELEG
HHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]