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The map label for this gene is aroB

Identifier: 78189186

GI number: 78189186

Start: 1617127

End: 1618224

Strand: Reverse

Name: aroB

Synonym: Cag_1219

Alternate gene names: 78189186

Gene position: 1618224-1617127 (Counterclockwise)

Preceding gene: 78189187

Following gene: 78189183

Centisome position: 62.92

GC content: 47.54

Gene sequence:

>1098_bases
ATGAGCACCATTATTGTAAAAACTCCCGTTACGGTTGGCTTACAAGAGCTTTTTCGTGAACATAAGCTGAGCAAAAAGTC
GGTGGTCCTGTTTGATAGCAATACGCGCAAACTGTTTGGCGATGTGGTGCTTGAGGCGTTGCGTGCCGAGGGTTTTCAGT
TGGTGGAGTTGGTAATTCCAGCGCGTGAGGCTTCGAAAAGTTTTAGTGTGGCGTATCGGCTTTATGGGCAGATGATTGAG
GCTGATGTTGATCGTAGTTGGAATTTATTGGCGGTTGGCGGTGGCGTGGTGGGTGATTTGGGTGGATTTATTGCAGCAAG
TTACTTCCGCGGCATTCCCGTTATTCAAATGCCGACAACGTTGCTTGCCATGACCGATAGCGCTATTGGTGGTAAAGTGG
CTATTAACCATCCACTTGGCAAGAATTTAATTGGCTTTTTCCACCTGCCTGAATTGGTGTTGATTGATCCCGCTACGTTG
GCTTCGCTGCCACGTCGCGAAATTTATGCAGGGTTAGCTGAGGTGGTGAAGTATGGCTTTATTGCTGATGCCAATTTTTT
CGACATGTTGGAAGCCCATTTTAGCGAAGTGGCTACGTTGCAAGAGCCGTACCTTACCGAAGCGGTAAAAACCAGCGCTC
TTATTAAGCAGGATGTGGTAACGCGCGATTTTCGTGAGTTGGATGGTTTGCGTGCCACCTTGAACTTTGGGCACACCTTT
GCGCATGGCTTAGAAAAACTTGCGGATTACCGCCATTTGCGCCATGGTGAAGCGGTTACTATGGGTTTGGTGTGTGCGTT
GTACCTTTCGCATCGTCTCGGTTTTCTTGATGCGCCGTCGCTTGAGCGAGGTTTGCGTTTGCTGCAACAATTTGTTTTCC
CCAAAAATGTGGTGGAGCGTTACTTTCTTGCCAGCAATAGCGCTTTGCTGCTTGAAAGCATGTTTTCTGATAAAAAGAAG
CTTGATAAAAAGCTCCGTTTTGTGCTGCTGAAGGAGCTTGGGCAAGCCTTTTTATTTGAAGAATCGGTGGAGGATAGCGA
GGTGTTGGCGGCTATTGAATCCGCTAAAGAGTGCTTTCGTCAGTGGCAACAAAAGTAA

Upstream 100 bases:

>100_bases
CGTCGGAGGAGTGAAGCGCACGTTTCTTCACCCGTTCATGTCAAGTGCTTTTTGTTATGCCCATTTCCTCATTAATTCTT
TCTCTTGATATAAAAAAAAG

Downstream 100 bases:

>100_bases
AGAAAATGTACTGATAACGCGGTGCCTCTCCTATAGGAGGGGAATTAGTATCACAGTGCATCCAGCTCAATCCCCAAATA
GCAAATGCACAACCCACCCT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSTIIVKTPVTVGLQELFREHKLSKKSVVLFDSNTRKLFGDVVLEALRAEGFQLVELVIPAREASKSFSVAYRLYGQMIE
ADVDRSWNLLAVGGGVVGDLGGFIAASYFRGIPVIQMPTTLLAMTDSAIGGKVAINHPLGKNLIGFFHLPELVLIDPATL
ASLPRREIYAGLAEVVKYGFIADANFFDMLEAHFSEVATLQEPYLTEAVKTSALIKQDVVTRDFRELDGLRATLNFGHTF
AHGLEKLADYRHLRHGEAVTMGLVCALYLSHRLGFLDAPSLERGLRLLQQFVFPKNVVERYFLASNSALLLESMFSDKKK
LDKKLRFVLLKELGQAFLFEESVEDSEVLAAIESAKECFRQWQQK

Sequences:

>Translated_365_residues
MSTIIVKTPVTVGLQELFREHKLSKKSVVLFDSNTRKLFGDVVLEALRAEGFQLVELVIPAREASKSFSVAYRLYGQMIE
ADVDRSWNLLAVGGGVVGDLGGFIAASYFRGIPVIQMPTTLLAMTDSAIGGKVAINHPLGKNLIGFFHLPELVLIDPATL
ASLPRREIYAGLAEVVKYGFIADANFFDMLEAHFSEVATLQEPYLTEAVKTSALIKQDVVTRDFRELDGLRATLNFGHTF
AHGLEKLADYRHLRHGEAVTMGLVCALYLSHRLGFLDAPSLERGLRLLQQFVFPKNVVERYFLASNSALLLESMFSDKKK
LDKKLRFVLLKELGQAFLFEESVEDSEVLAAIESAKECFRQWQQK
>Mature_364_residues
STIIVKTPVTVGLQELFREHKLSKKSVVLFDSNTRKLFGDVVLEALRAEGFQLVELVIPAREASKSFSVAYRLYGQMIEA
DVDRSWNLLAVGGGVVGDLGGFIAASYFRGIPVIQMPTTLLAMTDSAIGGKVAINHPLGKNLIGFFHLPELVLIDPATLA
SLPRREIYAGLAEVVKYGFIADANFFDMLEAHFSEVATLQEPYLTEAVKTSALIKQDVVTRDFRELDGLRATLNFGHTFA
HGLEKLADYRHLRHGEAVTMGLVCALYLSHRLGFLDAPSLERGLRLLQQFVFPKNVVERYFLASNSALLLESMFSDKKKL
DKKLRFVLLKELGQAFLFEESVEDSEVLAAIESAKECFRQWQQK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=314, Percent_Identity=39.8089171974522, Blast_Score=204, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320332, Length=361, Percent_Identity=34.6260387811634, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_CHLCH (Q3AR94)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379524.1
- ProteinModelPortal:   Q3AR94
- SMR:   Q3AR94
- STRING:   Q3AR94
- GeneID:   3748253
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1219
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   EKDFRET
- ProtClustDB:   PRK00002
- BioCyc:   CCHL340177:CAG_1219-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40718; Mature: 40587

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIVKTPVTVGLQELFREHKLSKKSVVLFDSNTRKLFGDVVLEALRAEGFQLVELVIP
CCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEHHHHHH
AREASKSFSVAYRLYGQMIEADVDRSWNLLAVGGGVVGDLGGFIAASYFRGIPVIQMPTT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEECCHH
LLAMTDSAIGGKVAINHPLGKNLIGFFHLPELVLIDPATLASLPRREIYAGLAEVVKYGF
HHHHHCCCCCCEEEECCCCCCCHHHHHCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHCC
IADANFFDMLEAHFSEVATLQEPYLTEAVKTSALIKQDVVTRDFRELDGLRATLNFGHTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHH
AHGLEKLADYRHLRHGEAVTMGLVCALYLSHRLGFLDAPSLERGLRLLQQFVFPKNVVER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHH
YFLASNSALLLESMFSDKKKLDKKLRFVLLKELGQAFLFEESVEDSEVLAAIESAKECFR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QWQQK
HHHCC
>Mature Secondary Structure 
STIIVKTPVTVGLQELFREHKLSKKSVVLFDSNTRKLFGDVVLEALRAEGFQLVELVIP
CEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEHHHHHH
AREASKSFSVAYRLYGQMIEADVDRSWNLLAVGGGVVGDLGGFIAASYFRGIPVIQMPTT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEECCHH
LLAMTDSAIGGKVAINHPLGKNLIGFFHLPELVLIDPATLASLPRREIYAGLAEVVKYGF
HHHHHCCCCCCEEEECCCCCCCHHHHHCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHCC
IADANFFDMLEAHFSEVATLQEPYLTEAVKTSALIKQDVVTRDFRELDGLRATLNFGHTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHH
AHGLEKLADYRHLRHGEAVTMGLVCALYLSHRLGFLDAPSLERGLRLLQQFVFPKNVVER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHH
YFLASNSALLLESMFSDKKKLDKKLRFVLLKELGQAFLFEESVEDSEVLAAIESAKECFR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QWQQK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA