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The map label for this gene is kefC [C]

Identifier: 78189172

GI number: 78189172

Start: 1602203

End: 1604353

Strand: Reverse

Name: kefC [C]

Synonym: Cag_1205

Alternate gene names: 78189172

Gene position: 1604353-1602203 (Counterclockwise)

Preceding gene: 78189176

Following gene: 78189171

Centisome position: 62.38

GC content: 40.77

Gene sequence:

>2151_bases
ATGCAGATGCACATAGCTCTACCACTACAAAATCCGGTGCTGCAATTCTCGTTGCTGCTTTTTATCATTCTATTTGCTCC
ATTGCTTTTCCGCCGTTTTAAACTTCCTGGGATTATTAGCTTAATTATAGCAGGAGCACTTATAGGACCACATGGTTTTA
ATTTGATGTTGCGCGATAGCAGTATTGTCTTATTTGGAACCGTGGGATTGCTCTATATTATGTTTCTTGCAGGTTTAGAA
ATTGATGTTGCTGATTTTCGTAAAAATAGTAGCAAAAGTATTCTTTTTGGACTCTATACCTTTTTTATATCAATTATTCT
TGGTATTGGTGTTGGTTACTATATCCTAAACTTTCCATTCCTCTCCTCTATTCTTATTGGCAGTATTTTTGCTTCTCACA
CGCTTATTATTTATCCAACAGTTAGCAAACTTGGTATTACTAAAAACAAGGCTGTAACGTTAGCTATTGGTGGCACCATT
GTTACCGATACGTTAGCCTTGCTGTTGCTTGCAGGTGTTGTAGGATTAGCCTCAGGTGAGTTAAACACCAATTTTTGGTT
ACGGTTATTGCTTGGTGTATTGCTTTTTGCAACCGTTATTCTGTGGGGTTTACCAATAGTTGCTCGTTGGTTTTTTAAGC
GTTTTGATGATAGTGTTTTACAATATCTTTTTGTGCTGGCACTTGTTTTTTTTAGTGCATTTTTAGCCGAAGCCGCAGGG
GTTGAACCTATTATTGGAGCCTTTTTTGGTGGCATTGCATTAAACCGTTTGATTCCTCGCACCTCTTCGCTTATGAATCG
AATTAAATTTGTGGGTAATGCGCTTTTTATTCCTTTTTTTTTAATTGGCGTTGGAATGCTTATTGATATTCACGCTTTTT
TTAAAGGATATGAAACTATTTTGGTCGCTTTTGTTATAACCGTATCGGCAACGGTAGCAAAATATAGCGCAGCATGGATT
GCTCAAAAAATGTATGGTTTTTCTATAGAACAGCGTCGTTTAATATTTGGATTAATTAGTGCTCATGCAGCCGTGGCGCT
TGCAACTGTGATGATTGGCTATGGTGTGATTATAGGAAAAGATGTTACGGGTCAACCTATCCGTTTATTAGACGAAAGTG
TACTGAATGGTACCATTCTTTTTGTGCTGCTAACCTGCACTTTGGCAACGTTTGTGGGTGAAAAAGGAGCCTACGCACTT
GCGGGTCAGCAGGAATTAGCCGAGCCTGAACACTTATTACCATCAGATGCTCCAACAAACCGCTTCTTGTTGCATATTAA
TCATATGGGAACGGTAAAAGAGTTGGTGAATGTAAGCGGCATGATGGTTACAGGTAAAATGCCGTATTCATTGTATGGGG
CGTACATTGCTACCACCCGTGAGATGGAGGTGAACCATGAATATCGAGCTGAAAAAATGCTGGAACGTGCTGTTATTAGT
GCTGGCGCCGCCGACCGTCATGTAACTCCGCTGCTTCGTTACGATACCTCGATTGCCAATGGTTTAGCTGGGGTTATTTG
TGAGCAAAAAATTAGCGATTTGTTCGTTTGCGTTGAACCAAGTAGCGATTTTCCTGATACACTCTCAATTAATAAGCCCG
ATAACATTCTTGGGCGCTGTGGTGTTACAACCTTTATTTATCGCCCAACGCAACCCTTTGCCACTATTAAACGCACCATT
GCCGTTGTGCCCGACGGCGCTGAGGCTGATCCGGGTTTTCGCCATTGGCTTGAACGGTTGCATGGCTTAATACAGCATAG
TCGTAGCTTGCTTATGGTATATGCTTCAACTCAAACAACTGATGCAATAAAAGCAACGGAAATAATGCCTATAATTGTTG
AGTACAAACGCTTTCGAGGATGGGAAAATTTTACCTTGCTTTCACAAATTATTCGGAAAGATGATTTAATGGTGCTTGTA
ATGAGCCGTCGCAATAATCCAGCGTGGCATCATCGGATGGCAACTATTCCAGCCATGTTGCATCGCTATTTTCAGCAAAA
CAGCTATCTCTTAATTTACCCGCTGCAAAATAACATGTCCACAGCGCTTGAAGAGGAAAATGCTGTTACTACCTACACGC
AACATCTTGGCAATGTGGCAAAGGTTAGTGGATGGGTAAAGCAGCTTGTTCGTGGGAAACAAAGTAGTTAA

Upstream 100 bases:

>100_bases
TGCTTATTAGTGTTGGTGGTATGGTTACTGTTCAACGTAAGAGCGCTCAAAAGGGGCGCAGTTGGGTAGAGTAGCACTTT
AAAAATTATTGAGGATAATT

Downstream 100 bases:

>100_bases
TTTTTTATTTATCCATCAGGGTTAGATTATAGCAATGATCTGTTAAGAGAAAAGCTATAATTTTTATATATGTTTCAATT
GCATGTTCAAAATTGAAAGT

Product: Na+/H+ anti-porter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MQMHIALPLQNPVLQFSLLLFIILFAPLLFRRFKLPGIISLIIAGALIGPHGFNLMLRDSSIVLFGTVGLLYIMFLAGLE
IDVADFRKNSSKSILFGLYTFFISIILGIGVGYYILNFPFLSSILIGSIFASHTLIIYPTVSKLGITKNKAVTLAIGGTI
VTDTLALLLLAGVVGLASGELNTNFWLRLLLGVLLFATVILWGLPIVARWFFKRFDDSVLQYLFVLALVFFSAFLAEAAG
VEPIIGAFFGGIALNRLIPRTSSLMNRIKFVGNALFIPFFLIGVGMLIDIHAFFKGYETILVAFVITVSATVAKYSAAWI
AQKMYGFSIEQRRLIFGLISAHAAVALATVMIGYGVIIGKDVTGQPIRLLDESVLNGTILFVLLTCTLATFVGEKGAYAL
AGQQELAEPEHLLPSDAPTNRFLLHINHMGTVKELVNVSGMMVTGKMPYSLYGAYIATTREMEVNHEYRAEKMLERAVIS
AGAADRHVTPLLRYDTSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRCGVTTFIYRPTQPFATIKRTI
AVVPDGAEADPGFRHWLERLHGLIQHSRSLLMVYASTQTTDAIKATEIMPIIVEYKRFRGWENFTLLSQIIRKDDLMVLV
MSRRNNPAWHHRMATIPAMLHRYFQQNSYLLIYPLQNNMSTALEEENAVTTYTQHLGNVAKVSGWVKQLVRGKQSS

Sequences:

>Translated_716_residues
MQMHIALPLQNPVLQFSLLLFIILFAPLLFRRFKLPGIISLIIAGALIGPHGFNLMLRDSSIVLFGTVGLLYIMFLAGLE
IDVADFRKNSSKSILFGLYTFFISIILGIGVGYYILNFPFLSSILIGSIFASHTLIIYPTVSKLGITKNKAVTLAIGGTI
VTDTLALLLLAGVVGLASGELNTNFWLRLLLGVLLFATVILWGLPIVARWFFKRFDDSVLQYLFVLALVFFSAFLAEAAG
VEPIIGAFFGGIALNRLIPRTSSLMNRIKFVGNALFIPFFLIGVGMLIDIHAFFKGYETILVAFVITVSATVAKYSAAWI
AQKMYGFSIEQRRLIFGLISAHAAVALATVMIGYGVIIGKDVTGQPIRLLDESVLNGTILFVLLTCTLATFVGEKGAYAL
AGQQELAEPEHLLPSDAPTNRFLLHINHMGTVKELVNVSGMMVTGKMPYSLYGAYIATTREMEVNHEYRAEKMLERAVIS
AGAADRHVTPLLRYDTSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRCGVTTFIYRPTQPFATIKRTI
AVVPDGAEADPGFRHWLERLHGLIQHSRSLLMVYASTQTTDAIKATEIMPIIVEYKRFRGWENFTLLSQIIRKDDLMVLV
MSRRNNPAWHHRMATIPAMLHRYFQQNSYLLIYPLQNNMSTALEEENAVTTYTQHLGNVAKVSGWVKQLVRGKQSS
>Mature_716_residues
MQMHIALPLQNPVLQFSLLLFIILFAPLLFRRFKLPGIISLIIAGALIGPHGFNLMLRDSSIVLFGTVGLLYIMFLAGLE
IDVADFRKNSSKSILFGLYTFFISIILGIGVGYYILNFPFLSSILIGSIFASHTLIIYPTVSKLGITKNKAVTLAIGGTI
VTDTLALLLLAGVVGLASGELNTNFWLRLLLGVLLFATVILWGLPIVARWFFKRFDDSVLQYLFVLALVFFSAFLAEAAG
VEPIIGAFFGGIALNRLIPRTSSLMNRIKFVGNALFIPFFLIGVGMLIDIHAFFKGYETILVAFVITVSATVAKYSAAWI
AQKMYGFSIEQRRLIFGLISAHAAVALATVMIGYGVIIGKDVTGQPIRLLDESVLNGTILFVLLTCTLATFVGEKGAYAL
AGQQELAEPEHLLPSDAPTNRFLLHINHMGTVKELVNVSGMMVTGKMPYSLYGAYIATTREMEVNHEYRAEKMLERAVIS
AGAADRHVTPLLRYDTSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRCGVTTFIYRPTQPFATIKRTI
AVVPDGAEADPGFRHWLERLHGLIQHSRSLLMVYASTQTTDAIKATEIMPIIVEYKRFRGWENFTLLSQIIRKDDLMVLV
MSRRNNPAWHHRMATIPAMLHRYFQQNSYLLIYPLQNNMSTALEEENAVTTYTQHLGNVAKVSGWVKQLVRGKQSS

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=394, Percent_Identity=23.8578680203046, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 79235; Mature: 79235

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMHIALPLQNPVLQFSLLLFIILFAPLLFRRFKLPGIISLIIAGALIGPHGFNLMLRDS
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECC
SIVLFGTVGLLYIMFLAGLEIDVADFRKNSSKSILFGLYTFFISIILGIGVGYYILNFPF
CEEEHHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSILIGSIFASHTLIIYPTVSKLGITKNKAVTLAIGGTIVTDTLALLLLAGVVGLASGE
HHHHHHHHHHHCCEEEEEECHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
LNTNFWLRLLLGVLLFATVILWGLPIVARWFFKRFDDSVLQYLFVLALVFFSAFLAEAAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEPIIGAFFGGIALNRLIPRTSSLMNRIKFVGNALFIPFFLIGVGMLIDIHAFFKGYETI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAFVITVSATVAKYSAAWIAQKMYGFSIEQRRLIFGLISAHAAVALATVMIGYGVIIGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
DVTGQPIRLLDESVLNGTILFVLLTCTLATFVGEKGAYALAGQQELAEPEHLLPSDAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCHHCCCCCCCCC
RFLLHINHMGTVKELVNVSGMMVTGKMPYSLYGAYIATTREMEVNHEYRAEKMLERAVIS
EEEEEEECCHHHHHHHCCCCEEEECCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHH
AGAADRHVTPLLRYDTSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRC
CCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHC
GVTTFIYRPTQPFATIKRTIAVVPDGAEADPGFRHWLERLHGLIQHSRSLLMVYASTQTT
CCEEEEECCCCCHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCC
DAIKATEIMPIIVEYKRFRGWENFTLLSQIIRKDDLMVLVMSRRNNPAWHHRMATIPAML
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
HRYFQQNSYLLIYPLQNNMSTALEEENAVTTYTQHLGNVAKVSGWVKQLVRGKQSS
HHHHHCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQMHIALPLQNPVLQFSLLLFIILFAPLLFRRFKLPGIISLIIAGALIGPHGFNLMLRDS
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECC
SIVLFGTVGLLYIMFLAGLEIDVADFRKNSSKSILFGLYTFFISIILGIGVGYYILNFPF
CEEEHHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSILIGSIFASHTLIIYPTVSKLGITKNKAVTLAIGGTIVTDTLALLLLAGVVGLASGE
HHHHHHHHHHHCCEEEEEECHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
LNTNFWLRLLLGVLLFATVILWGLPIVARWFFKRFDDSVLQYLFVLALVFFSAFLAEAAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEPIIGAFFGGIALNRLIPRTSSLMNRIKFVGNALFIPFFLIGVGMLIDIHAFFKGYETI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAFVITVSATVAKYSAAWIAQKMYGFSIEQRRLIFGLISAHAAVALATVMIGYGVIIGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
DVTGQPIRLLDESVLNGTILFVLLTCTLATFVGEKGAYALAGQQELAEPEHLLPSDAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCHHCCCCCCCCC
RFLLHINHMGTVKELVNVSGMMVTGKMPYSLYGAYIATTREMEVNHEYRAEKMLERAVIS
EEEEEEECCHHHHHHHCCCCEEEECCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHH
AGAADRHVTPLLRYDTSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRC
CCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHC
GVTTFIYRPTQPFATIKRTIAVVPDGAEADPGFRHWLERLHGLIQHSRSLLMVYASTQTT
CCEEEEECCCCCHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCC
DAIKATEIMPIIVEYKRFRGWENFTLLSQIIRKDDLMVLVMSRRNNPAWHHRMATIPAML
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
HRYFQQNSYLLIYPLQNNMSTALEEENAVTTYTQHLGNVAKVSGWVKQLVRGKQSS
HHHHHCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]