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The map label for this gene is prsA [H]

Identifier: 78189176

GI number: 78189176

Start: 1607777

End: 1609870

Strand: Reverse

Name: prsA [H]

Synonym: Cag_1209

Alternate gene names: 78189176

Gene position: 1609870-1607777 (Counterclockwise)

Preceding gene: 78189177

Following gene: 78189172

Centisome position: 62.59

GC content: 47.28

Gene sequence:

>2094_bases
ATGGCATTACTTTCAAGCTTACGCAACAAAACACATATCATTCTCTATGTGCTGTTAGCCTCATTTCTTGCCCTTATTGT
TTTTGAATGGGGCATGGAAAGCAATTTTATAAAACCGCAAAATGTTGCGGGCAAAGTAAATGGCGCTTCAATTTCGTATC
AAGAGTATGATAATGCCTATAAAGCGCTTTCAGAAAATGTGCGGCGAGCAAATCCTGAGCTTGAACTAACGCCCGAAATG
GAGCATGAGTTGCAAGAGCGTGCATGGAATAGCTTAGTAGATCAGCGTTTGCTTGAAGAGCAGTTCCGCAAGTTTGGCAT
TACGGTGCAAGATCGTGAAGTGCTTGAAGCTATGAATAGCCCTCAGCCACCAATGGTGATTCGCCAATATTTTACCGATC
CAGCAACTGGTAAGGTGGATCGCCAAAAGCTTGAAAGTGCGCGGCGCGATCCTGCCAATCGTGATATGTGGCTTCAGCTT
GAAAAATATGTGCGCATGGAGCTGCAAGAAAACAAGCTGTTGCGTGCTTTTCAAACCTTTGAGCGCGTAACTGACCGCGA
AATAAGCGATATGATAAACCGCAAAGTCTCGCTCTTTACGGCATCCTTTATCCCCCTACCACTTTCAGCCGCAGGCGACG
ATAAGCGCTTTCCCATCACCGATGACGACATAAAAAAATATTACGACGAGCATAAAGAGCAGTTCCGCCAAGAAAAGCCT
TCGCGCAAAGTGGAAACGGTTTTTTTTCCCCTTGTTCCCTCTGCAAAAGATAGCGCTGCGGTGCGCCAAGAGCTTGAAGC
GTTGCGTGCTGATTTTAGCAAATCGCAAAACGATGTTGATTTTGTAAAGGTGCAAAGCGATCGTTCCAACAGCGCAAACG
TTGTGCTAACGCGGGCTGATTTTTCGCCATTGGCAGGCAATGCCATTTTTAACACCTCATCACTTGCGGCGGGTTCGCTT
ATTGGTCCTTTTGCCGATAATGGCGAGTTTCGCTTGCTGAAAGTGGTGCGGGTGCAGCCAGCAGTTCAACCAATAGCGCG
TGCTTCGCACATTTTGCTTCGCTTTAATCCTGCAAATAAAGCTGAGATTGAAAAGGTGCAGCAACTCACCATGCAGATAG
GGCAGCAACTACAAGCAGGTGTGCCTTTTGAAACGCTTGCCAAACAATATTCGGCTGACCCTGGTAGTGCCGAAAATGGT
GGCGATCTTGGCTGGTTTAGCCCAGACCGCATGGTGCCGGAATTTTCTAAAGCGGTGTTTAATAGTCGCCCGGGTGCAAT
TATTGGACCTATTCAAACACAATTTGGCGTGCATATTATTAAAGTAACAGGCTTTGACCAACGGGCGTTAGTTGCCTCCG
AAGTGGTGCGCACCATTCGCTCATCAAGCGAAAGTATGGAGAGCCAACGCCGCCGTGCTATGGCATTTCAAGTTGATGCA
AAAGAGAAGGGATTTGCAAAAAGCGCCGCCACGGCTGGCGTAAAAGTTGAAGAGAGCAATGAGTTTACACGCCGAATGGC
TATTCGCCCACTTGGCTATAACGATAAAGTAGCAACCTTTGCCTTTAGCGCTAAGGAAGGCGACATTTCCGATGTTATTG
AAAGCAAGAAGGGCTTTTATGTTGCTCGCTTAACGGCAAAGCATGACGAGGGCTACCGTTCACTTGATAAAGATGCAAAA
GAGCGCATTAAGCAAGAGCTACTTGTTGAGAAAAAAGGAGCGGCGTTACAGCAAAAACTGACCGCAGCGGCTAAAGTTCC
CAATGCTACACTTGAGCAAATTGCAGCTCGTGTTGGTAGTCAAGTAGTACATGCTGATGGCATTCGTTGGGCTGATGGCT
TTATTCCCAACTATGGCGTGGATCGTGTGTTGGTGGAAGCAATTTCGGGTATGACGGCGGGCAAGCTTTTCAAGCCGGTA
AAAACCAGCAATGGCTATGCACTTGTGCGGCTTGAGCGTAAAAGTATTCCTGAGGGTTTTGATCCAAATGCGGTAAAAGG
CATGGTAGCTCCACAGCTTTTGCAAGCCAAGCATCAGCAGCTCTTTACGGAGTATTTTCAATCGCTTCGCAACGTTGAGG
ATTTGCGCCCGTAA

Upstream 100 bases:

>100_bases
CTTTCTTGGGCATTACGATGATAAGTAATAGCTCTTTATTTCATGGCAACAGTAACCGCTCAACATAATCTGATTTTCTT
TTATCAAACCAATAAACATC

Downstream 100 bases:

>100_bases
AGCTGTAGAGAGCGGGAAAGTGAAACGGTTTTGTTTCCCCATGAAACTCGTGATTAAAAGGGAGTGCTTATGAGTAGTAG
GCACTCCCTTTTTGCGAATA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MALLSSLRNKTHIILYVLLASFLALIVFEWGMESNFIKPQNVAGKVNGASISYQEYDNAYKALSENVRRANPELELTPEM
EHELQERAWNSLVDQRLLEEQFRKFGITVQDREVLEAMNSPQPPMVIRQYFTDPATGKVDRQKLESARRDPANRDMWLQL
EKYVRMELQENKLLRAFQTFERVTDREISDMINRKVSLFTASFIPLPLSAAGDDKRFPITDDDIKKYYDEHKEQFRQEKP
SRKVETVFFPLVPSAKDSAAVRQELEALRADFSKSQNDVDFVKVQSDRSNSANVVLTRADFSPLAGNAIFNTSSLAAGSL
IGPFADNGEFRLLKVVRVQPAVQPIARASHILLRFNPANKAEIEKVQQLTMQIGQQLQAGVPFETLAKQYSADPGSAENG
GDLGWFSPDRMVPEFSKAVFNSRPGAIIGPIQTQFGVHIIKVTGFDQRALVASEVVRTIRSSSESMESQRRRAMAFQVDA
KEKGFAKSAATAGVKVEESNEFTRRMAIRPLGYNDKVATFAFSAKEGDISDVIESKKGFYVARLTAKHDEGYRSLDKDAK
ERIKQELLVEKKGAALQQKLTAAAKVPNATLEQIAARVGSQVVHADGIRWADGFIPNYGVDRVLVEAISGMTAGKLFKPV
KTSNGYALVRLERKSIPEGFDPNAVKGMVAPQLLQAKHQQLFTEYFQSLRNVEDLRP

Sequences:

>Translated_697_residues
MALLSSLRNKTHIILYVLLASFLALIVFEWGMESNFIKPQNVAGKVNGASISYQEYDNAYKALSENVRRANPELELTPEM
EHELQERAWNSLVDQRLLEEQFRKFGITVQDREVLEAMNSPQPPMVIRQYFTDPATGKVDRQKLESARRDPANRDMWLQL
EKYVRMELQENKLLRAFQTFERVTDREISDMINRKVSLFTASFIPLPLSAAGDDKRFPITDDDIKKYYDEHKEQFRQEKP
SRKVETVFFPLVPSAKDSAAVRQELEALRADFSKSQNDVDFVKVQSDRSNSANVVLTRADFSPLAGNAIFNTSSLAAGSL
IGPFADNGEFRLLKVVRVQPAVQPIARASHILLRFNPANKAEIEKVQQLTMQIGQQLQAGVPFETLAKQYSADPGSAENG
GDLGWFSPDRMVPEFSKAVFNSRPGAIIGPIQTQFGVHIIKVTGFDQRALVASEVVRTIRSSSESMESQRRRAMAFQVDA
KEKGFAKSAATAGVKVEESNEFTRRMAIRPLGYNDKVATFAFSAKEGDISDVIESKKGFYVARLTAKHDEGYRSLDKDAK
ERIKQELLVEKKGAALQQKLTAAAKVPNATLEQIAARVGSQVVHADGIRWADGFIPNYGVDRVLVEAISGMTAGKLFKPV
KTSNGYALVRLERKSIPEGFDPNAVKGMVAPQLLQAKHQQLFTEYFQSLRNVEDLRP
>Mature_696_residues
ALLSSLRNKTHIILYVLLASFLALIVFEWGMESNFIKPQNVAGKVNGASISYQEYDNAYKALSENVRRANPELELTPEME
HELQERAWNSLVDQRLLEEQFRKFGITVQDREVLEAMNSPQPPMVIRQYFTDPATGKVDRQKLESARRDPANRDMWLQLE
KYVRMELQENKLLRAFQTFERVTDREISDMINRKVSLFTASFIPLPLSAAGDDKRFPITDDDIKKYYDEHKEQFRQEKPS
RKVETVFFPLVPSAKDSAAVRQELEALRADFSKSQNDVDFVKVQSDRSNSANVVLTRADFSPLAGNAIFNTSSLAAGSLI
GPFADNGEFRLLKVVRVQPAVQPIARASHILLRFNPANKAEIEKVQQLTMQIGQQLQAGVPFETLAKQYSADPGSAENGG
DLGWFSPDRMVPEFSKAVFNSRPGAIIGPIQTQFGVHIIKVTGFDQRALVASEVVRTIRSSSESMESQRRRAMAFQVDAK
EKGFAKSAATAGVKVEESNEFTRRMAIRPLGYNDKVATFAFSAKEGDISDVIESKKGFYVARLTAKHDEGYRSLDKDAKE
RIKQELLVEKKGAALQQKLTAAAKVPNATLEQIAARVGSQVVHADGIRWADGFIPNYGVDRVLVEAISGMTAGKLFKPVK
TSNGYALVRLERKSIPEGFDPNAVKGMVAPQLLQAKHQQLFTEYFQSLRNVEDLRP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=205, Percent_Identity=29.2682926829268, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790211, Length=78, Percent_Identity=44.8717948717949, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 78176; Mature: 78045

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLSSLRNKTHIILYVLLASFLALIVFEWGMESNFIKPQNVAGKVNGASISYQEYDNAY
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHHHHHH
KALSENVRRANPELELTPEMEHELQERAWNSLVDQRLLEEQFRKFGITVQDREVLEAMNS
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
PQPPMVIRQYFTDPATGKVDRQKLESARRDPANRDMWLQLEKYVRMELQENKLLRAFQTF
CCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERVTDREISDMINRKVSLFTASFIPLPLSAAGDDKRFPITDDDIKKYYDEHKEQFRQEKP
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SRKVETVFFPLVPSAKDSAAVRQELEALRADFSKSQNDVDFVKVQSDRSNSANVVLTRAD
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECC
FSPLAGNAIFNTSSLAAGSLIGPFADNGEFRLLKVVRVQPAVQPIARASHILLRFNPANK
CCCCCCCCEECCCHHCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHCEEEEEECCCCH
AEIEKVQQLTMQIGQQLQAGVPFETLAKQYSADPGSAENGGDLGWFSPDRMVPEFSKAVF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NSRPGAIIGPIQTQFGVHIIKVTGFDQRALVASEVVRTIRSSSESMESQRRRAMAFQVDA
CCCCCCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
KEKGFAKSAATAGVKVEESNEFTRRMAIRPLGYNDKVATFAFSAKEGDISDVIESKKGFY
CCCCCHHHHHHCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCEE
VARLTAKHDEGYRSLDKDAKERIKQELLVEKKGAALQQKLTAAAKVPNATLEQIAARVGS
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
QVVHADGIRWADGFIPNYGVDRVLVEAISGMTAGKLFKPVKTSNGYALVRLERKSIPEGF
CEECCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEEHHCCCCCC
DPNAVKGMVAPQLLQAKHQQLFTEYFQSLRNVEDLRP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALLSSLRNKTHIILYVLLASFLALIVFEWGMESNFIKPQNVAGKVNGASISYQEYDNAY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHHHHHH
KALSENVRRANPELELTPEMEHELQERAWNSLVDQRLLEEQFRKFGITVQDREVLEAMNS
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
PQPPMVIRQYFTDPATGKVDRQKLESARRDPANRDMWLQLEKYVRMELQENKLLRAFQTF
CCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERVTDREISDMINRKVSLFTASFIPLPLSAAGDDKRFPITDDDIKKYYDEHKEQFRQEKP
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SRKVETVFFPLVPSAKDSAAVRQELEALRADFSKSQNDVDFVKVQSDRSNSANVVLTRAD
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECC
FSPLAGNAIFNTSSLAAGSLIGPFADNGEFRLLKVVRVQPAVQPIARASHILLRFNPANK
CCCCCCCCEECCCHHCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHCEEEEEECCCCH
AEIEKVQQLTMQIGQQLQAGVPFETLAKQYSADPGSAENGGDLGWFSPDRMVPEFSKAVF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NSRPGAIIGPIQTQFGVHIIKVTGFDQRALVASEVVRTIRSSSESMESQRRRAMAFQVDA
CCCCCCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
KEKGFAKSAATAGVKVEESNEFTRRMAIRPLGYNDKVATFAFSAKEGDISDVIESKKGFY
CCCCCHHHHHHCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCEE
VARLTAKHDEGYRSLDKDAKERIKQELLVEKKGAALQQKLTAAAKVPNATLEQIAARVGS
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
QVVHADGIRWADGFIPNYGVDRVLVEAISGMTAGKLFKPVKTSNGYALVRLERKSIPEGF
CEECCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEEHHCCCCCC
DPNAVKGMVAPQLLQAKHQQLFTEYFQSLRNVEDLRP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA