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The map label for this gene is inlA [H]

Identifier: 78188862

GI number: 78188862

Start: 1222701

End: 1224104

Strand: Reverse

Name: inlA [H]

Synonym: Cag_0892

Alternate gene names: 78188862

Gene position: 1224104-1222701 (Counterclockwise)

Preceding gene: 78188864

Following gene: 78188861

Centisome position: 47.59

GC content: 43.45

Gene sequence:

>1404_bases
ATGGCACTTCGGCTTTTTTTCTCTATTTTTAAAGAACTTAAAAGCAGCGCGGTTCCTCAGAGTCCTCTTGTTCCTTTAAG
TAGTGATGGAATTTTTTGGTACCAAAAAGCGCTACTTCCCATTGCAATTAAGAAAATGGAAGTGCGCCAAAGTACAAACC
AGCTCGTTATCTCCCCAACCTTAAACGCACTTTTAATTGTGGAGCAACATACCTACAACCAATGCCCAGTGTGCGGTTTT
CCGCTTTCCATGAATAGCGCTATTTGCCCTCGTTGTGGCAACGATATTCTTGAAGATATTTCATCACTCGATCAACAATC
GTTGGAGAGGTATCATAAACATCTTGAAAACAAAAAAGCAGAGTGGTACGCCCGTTGCTTAACCGATCAAATTACTGGTG
GCGACAACCCACCCTTATCAGCCGAGCACCAAGAGTGCCCAGCAGGACGCCAAAAGCCTCACGCTTTGTTTAATAGTGAT
GACGAGTTGGCATTTTTTACCTCATTAAACCGTGCCGATATTCTGCGCGACACAAATTTGCGCAAAAAGTGGTGGCAAAG
CATTACTGCCGATTGGCAAGATGTGGTACGTTTCACCTTAAAAATTAATCACGATCCTTCCGATAGCGACTTACTTGCTT
TTTTTGATAGCACCAATTTGCGTTGTGATGACCGTCGCATTCATAGCTTGCTGCCTATTCGCGTACTCGAAAAGCTTCAG
CAACTTCGTTGCGATGAATCGCCCATTGAAAGCCTTGAGCCTCTTGCCCACCTTACCTTGTTGCAGCGACTTTATGCCTT
TGATTGCGACTTTACCTCATTGGAACCGCTGCGTAACCTAACGCATCTTAAACTCCTATGGATTTCAAGCACCGAAATCA
CATCGCTTGAACCCATTAGTAACCTTATTAATCTCGAAGAGCTTTATTGCTCCGAAACCGACATTACCGATTTAGAGCCA
CTTCGGAAGCTTATCAATCTCGAAAAGCTAAGCTGCTACAAAACCAGCATTACCTCCTTAGAGCCACTTGCTGAACTTGA
AAATTTAATTGAGCTGGGCATTAATCACTCCGATATTAATGATTTAACCCCTCTTGCAGGGCTTATCAATCTTGAATACT
TGCGCTGTAGTAAAACCGCTATTAGCAGCTTAGAACCGTTGCGCAACATGGTAGAGTTGCGGGAACTCAGCATTGCTCAT
ACCAATGTAGATTCGTTAGAAGGCTTGCAAGGGTTAGAAAATCTTGAAGAGCTTGATATTACGAACACCTTGGTAAGTTC
TATTGAACCGCTTATGGGGTTGGAATACATCGAAAAGCTTGAGCTTTCGGTTGGCACCATTCCTGACGAAGAGCTTGAGC
GCTTTGTAGAATTACATCCCGATTGCAATGTTGTTGCAAAGTAG

Upstream 100 bases:

>100_bases
AATGGTTGGCTATCACGCTATCAAGTGCTTAAAAGGCATCCTTAACACCAATGAATGGAACGTGAAAAAAGGGTTAACGC
CTTATAAAGGGCATCCATCT

Downstream 100 bases:

>100_bases
ATCTCTGATTGAATTGTAGAGATAACGTTATGCGTTGTCTCTACGCCAAAATTTAACCACAAATGAAGGAGTAAAATTAT
GGCACAAAGAGCATTGCTTG

Product: internalin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MALRLFFSIFKELKSSAVPQSPLVPLSSDGIFWYQKALLPIAIKKMEVRQSTNQLVISPTLNALLIVEQHTYNQCPVCGF
PLSMNSAICPRCGNDILEDISSLDQQSLERYHKHLENKKAEWYARCLTDQITGGDNPPLSAEHQECPAGRQKPHALFNSD
DELAFFTSLNRADILRDTNLRKKWWQSITADWQDVVRFTLKINHDPSDSDLLAFFDSTNLRCDDRRIHSLLPIRVLEKLQ
QLRCDESPIESLEPLAHLTLLQRLYAFDCDFTSLEPLRNLTHLKLLWISSTEITSLEPISNLINLEELYCSETDITDLEP
LRKLINLEKLSCYKTSITSLEPLAELENLIELGINHSDINDLTPLAGLINLEYLRCSKTAISSLEPLRNMVELRELSIAH
TNVDSLEGLQGLENLEELDITNTLVSSIEPLMGLEYIEKLELSVGTIPDEELERFVELHPDCNVVAK

Sequences:

>Translated_467_residues
MALRLFFSIFKELKSSAVPQSPLVPLSSDGIFWYQKALLPIAIKKMEVRQSTNQLVISPTLNALLIVEQHTYNQCPVCGF
PLSMNSAICPRCGNDILEDISSLDQQSLERYHKHLENKKAEWYARCLTDQITGGDNPPLSAEHQECPAGRQKPHALFNSD
DELAFFTSLNRADILRDTNLRKKWWQSITADWQDVVRFTLKINHDPSDSDLLAFFDSTNLRCDDRRIHSLLPIRVLEKLQ
QLRCDESPIESLEPLAHLTLLQRLYAFDCDFTSLEPLRNLTHLKLLWISSTEITSLEPISNLINLEELYCSETDITDLEP
LRKLINLEKLSCYKTSITSLEPLAELENLIELGINHSDINDLTPLAGLINLEYLRCSKTAISSLEPLRNMVELRELSIAH
TNVDSLEGLQGLENLEELDITNTLVSSIEPLMGLEYIEKLELSVGTIPDEELERFVELHPDCNVVAK
>Mature_466_residues
ALRLFFSIFKELKSSAVPQSPLVPLSSDGIFWYQKALLPIAIKKMEVRQSTNQLVISPTLNALLIVEQHTYNQCPVCGFP
LSMNSAICPRCGNDILEDISSLDQQSLERYHKHLENKKAEWYARCLTDQITGGDNPPLSAEHQECPAGRQKPHALFNSDD
ELAFFTSLNRADILRDTNLRKKWWQSITADWQDVVRFTLKINHDPSDSDLLAFFDSTNLRCDDRRIHSLLPIRVLEKLQQ
LRCDESPIESLEPLAHLTLLQRLYAFDCDFTSLEPLRNLTHLKLLWISSTEITSLEPISNLINLEELYCSETDITDLEPL
RKLINLEKLSCYKTSITSLEPLAELENLIELGINHSDINDLTPLAGLINLEYLRCSKTAISSLEPLRNMVELRELSIAHT
NVDSLEGLQGLENLEELDITNTLVSSIEPLMGLEYIEKLELSVGTIPDEELERFVELHPDCNVVAK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=233, Percent_Identity=28.755364806867, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554124, Length=183, Percent_Identity=31.1475409836066, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358617, Length=213, Percent_Identity=30.5164319248826, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 53132; Mature: 53001

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRLFFSIFKELKSSAVPQSPLVPLSSDGIFWYQKALLPIAIKKMEVRQSTNQLVISPT
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
LNALLIVEQHTYNQCPVCGFPLSMNSAICPRCGNDILEDISSLDQQSLERYHKHLENKKA
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EWYARCLTDQITGGDNPPLSAEHQECPAGRQKPHALFNSDDELAFFTSLNRADILRDTNL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEECCCHHHHHHCCCH
RKKWWQSITADWQDVVRFTLKINHDPSDSDLLAFFDSTNLRCDDRRIHSLLPIRVLEKLQ
HHHHHHHHCCCHHHHHHEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
QLRCDESPIESLEPLAHLTLLQRLYAFDCDFTSLEPLRNLTHLKLLWISSTEITSLEPIS
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCHHHHH
NLINLEELYCSETDITDLEPLRKLINLEKLSCYKTSITSLEPLAELENLIELGINHSDIN
HHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLTPLAGLINLEYLRCSKTAISSLEPLRNMVELRELSIAHTNVDSLEGLQGLENLEELDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TNTLVSSIEPLMGLEYIEKLELSVGTIPDEELERFVELHPDCNVVAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALRLFFSIFKELKSSAVPQSPLVPLSSDGIFWYQKALLPIAIKKMEVRQSTNQLVISPT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
LNALLIVEQHTYNQCPVCGFPLSMNSAICPRCGNDILEDISSLDQQSLERYHKHLENKKA
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
EWYARCLTDQITGGDNPPLSAEHQECPAGRQKPHALFNSDDELAFFTSLNRADILRDTNL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEECCCHHHHHHCCCH
RKKWWQSITADWQDVVRFTLKINHDPSDSDLLAFFDSTNLRCDDRRIHSLLPIRVLEKLQ
HHHHHHHHCCCHHHHHHEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
QLRCDESPIESLEPLAHLTLLQRLYAFDCDFTSLEPLRNLTHLKLLWISSTEITSLEPIS
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCHHHHH
NLINLEELYCSETDITDLEPLRKLINLEKLSCYKTSITSLEPLAELENLIELGINHSDIN
HHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLTPLAGLINLEYLRCSKTAISSLEPLRNMVELRELSIAHTNVDSLEGLQGLENLEELDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TNTLVSSIEPLMGLEYIEKLELSVGTIPDEELERFVELHPDCNVVAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]