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The map label for this gene is nrnA [H]

Identifier: 78188795

GI number: 78188795

Start: 1150406

End: 1151470

Strand: Reverse

Name: nrnA [H]

Synonym: Cag_0824

Alternate gene names: 78188795

Gene position: 1151470-1150406 (Counterclockwise)

Preceding gene: 78188800

Following gene: 78188794

Centisome position: 44.77

GC content: 46.29

Gene sequence:

>1065_bases
ATGATTATTCCCTCCTACGGTCGCACCCTTCACGCTGAAGAGTGGCAACCGCTCCTTGAGCCGCTGCTTGCAGCTCAACA
CCTTGTTTTAACAACGCACGAAAATTCTGATGGCGATGGCTTAGGGTGCGAAGTTGCCCTTGCTCTTGCTCTTACGGCTC
TTGGCAAAGAGGTTTCCATTGTGAACCCAACGGAAGTACCGCCCAACTACCAATTTTTGAGGCAACTCTACCCAATAGTT
CAATTTAATCCCAAAAGTGAAGAGGCAATTCAAGAGCTTTCGCTGTGCGATGCCGTGGTGCTGCTTGATGCCAATTTAAG
CGACCGCATGGGAACCTTGTGGCCTCACGTTCGTTTTGCACGCGAGCTTGGTAGTTTAAAGCTTCTCTGCGTTGATCACC
ATCTTGAACCAAATGATTTTACCGATGTTATGATTTCGGAGTCGTATGCCTCCTCCACTGGCGAGTTAGTATATGGCTTA
ATTCTTGCTATGGAACAAAGTGTTGGGCGTGCGCTCTTTACACCCAATATTGCTCAAGCGCTCTATGTGGCGGTAATGAC
GGATACGGGTTCATTCCGATTTTCAAAAACAACTCCATACGTTTATCAATTAGCGGGCGATTTAGTGGCGCGTGGGGCTA
ATCCCGAAAAAGCATACGATTTAATTTTTAATTCGCTAACGCCTCAAGCGCTCAAATTACTTGGCTTGTCGTTAAGCGCT
ATTTCTCTTGTTGAGGGGGGAAAACTTTCGTGGCTGCTTATTTCACAAGAGATGTTAAAAGCAACGGAAAGTAAGTTGTT
TGATACTGATATTATTGTCCGTTATCTTTTAAGTGTGCCCTCAGTTGCCATAGCGGTACTTTTAGTTGAAATGCAAGATG
GACGTACCAAAGCAAGTTTTCGCTCGCGTGGCAAGTTGCCCGTTAATAAACTTGCTAAAGAATTTGGCGGCGGTGGGCAT
ATGAATGCGGCTGGTGCGCTTTTTCCCTATACGCCCGAAAAGGTACAACAAGTGCTTCCGCAAGCTGTGCGTCGCTTTAT
AAAAGAGCATGAAGCGCTGCTGTAA

Upstream 100 bases:

>100_bases
TACAAAACAGCGAAAAAAGGCTAAATTGCGCCGCTTCTTTTTTTACGATTGATAGCATGATGTACATTCTTTCTTTATTT
GTTACCGATTCGATTCTCGC

Downstream 100 bases:

>100_bases
CATATCTTTATTAAAAGAGTTAACATTATACTATCCACTGTTTATGAATATTCAGGTTACTGTTGAAGCGCTTGCAAATG
TGCAGGCGGAATTACTTGCA

Product: DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIIPSYGRTLHAEEWQPLLEPLLAAQHLVLTTHENSDGDGLGCEVALALALTALGKEVSIVNPTEVPPNYQFLRQLYPIV
QFNPKSEEAIQELSLCDAVVLLDANLSDRMGTLWPHVRFARELGSLKLLCVDHHLEPNDFTDVMISESYASSTGELVYGL
ILAMEQSVGRALFTPNIAQALYVAVMTDTGSFRFSKTTPYVYQLAGDLVARGANPEKAYDLIFNSLTPQALKLLGLSLSA
ISLVEGGKLSWLLISQEMLKATESKLFDTDIIVRYLLSVPSVAIAVLLVEMQDGRTKASFRSRGKLPVNKLAKEFGGGGH
MNAAGALFPYTPEKVQQVLPQAVRRFIKEHEALL

Sequences:

>Translated_354_residues
MIIPSYGRTLHAEEWQPLLEPLLAAQHLVLTTHENSDGDGLGCEVALALALTALGKEVSIVNPTEVPPNYQFLRQLYPIV
QFNPKSEEAIQELSLCDAVVLLDANLSDRMGTLWPHVRFARELGSLKLLCVDHHLEPNDFTDVMISESYASSTGELVYGL
ILAMEQSVGRALFTPNIAQALYVAVMTDTGSFRFSKTTPYVYQLAGDLVARGANPEKAYDLIFNSLTPQALKLLGLSLSA
ISLVEGGKLSWLLISQEMLKATESKLFDTDIIVRYLLSVPSVAIAVLLVEMQDGRTKASFRSRGKLPVNKLAKEFGGGGH
MNAAGALFPYTPEKVQQVLPQAVRRFIKEHEALL
>Mature_354_residues
MIIPSYGRTLHAEEWQPLLEPLLAAQHLVLTTHENSDGDGLGCEVALALALTALGKEVSIVNPTEVPPNYQFLRQLYPIV
QFNPKSEEAIQELSLCDAVVLLDANLSDRMGTLWPHVRFARELGSLKLLCVDHHLEPNDFTDVMISESYASSTGELVYGL
ILAMEQSVGRALFTPNIAQALYVAVMTDTGSFRFSKTTPYVYQLAGDLVARGANPEKAYDLIFNSLTPQALKLLGLSLSA
ISLVEGGKLSWLLISQEMLKATESKLFDTDIIVRYLLSVPSVAIAVLLVEMQDGRTKASFRSRGKLPVNKLAKEFGGGGH
MNAAGALFPYTPEKVQQVLPQAVRRFIKEHEALL

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 38835; Mature: 38835

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPSYGRTLHAEEWQPLLEPLLAAQHLVLTTHENSDGDGLGCEVALALALTALGKEVSI
CCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEE
VNPTEVPPNYQFLRQLYPIVQFNPKSEEAIQELSLCDAVVLLDANLSDRMGTLWPHVRFA
ECCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHH
RELGSLKLLCVDHHLEPNDFTDVMISESYASSTGELVYGLILAMEQSVGRALFTPNIAQA
HHHCCEEEEEEECCCCCCCCHHHEEECHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LYVAVMTDTGSFRFSKTTPYVYQLAGDLVARGANPEKAYDLIFNSLTPQALKLLGLSLSA
HEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCHHHH
ISLVEGGKLSWLLISQEMLKATESKLFDTDIIVRYLLSVPSVAIAVLLVEMQDGRTKASF
HHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHH
RSRGKLPVNKLAKEFGGGGHMNAAGALFPYTPEKVQQVLPQAVRRFIKEHEALL
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIPSYGRTLHAEEWQPLLEPLLAAQHLVLTTHENSDGDGLGCEVALALALTALGKEVSI
CCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEE
VNPTEVPPNYQFLRQLYPIVQFNPKSEEAIQELSLCDAVVLLDANLSDRMGTLWPHVRFA
ECCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHH
RELGSLKLLCVDHHLEPNDFTDVMISESYASSTGELVYGLILAMEQSVGRALFTPNIAQA
HHHCCEEEEEEECCCCCCCCHHHEEECHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LYVAVMTDTGSFRFSKTTPYVYQLAGDLVARGANPEKAYDLIFNSLTPQALKLLGLSLSA
HEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCHHHH
ISLVEGGKLSWLLISQEMLKATESKLFDTDIIVRYLLSVPSVAIAVLLVEMQDGRTKASF
HHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHH
RSRGKLPVNKLAKEFGGGGHMNAAGALFPYTPEKVQQVLPQAVRRFIKEHEALL
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]