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The map label for this gene is udg [H]

Identifier: 78188792

GI number: 78188792

Start: 1146374

End: 1147711

Strand: Reverse

Name: udg [H]

Synonym: Cag_0821

Alternate gene names: 78188792

Gene position: 1147711-1146374 (Counterclockwise)

Preceding gene: 78188793

Following gene: 78188791

Centisome position: 44.62

GC content: 47.61

Gene sequence:

>1338_bases
ATGAAAATAACCATCTTTGGCTCGGGCTATGTGGGATTAGTAACGGGTGCATGTTTTGCAAAAGTTGGCAACGATGTGCT
CTGCGTTGATATTGACGAGAATAAAATTAATCGCCTTCGTAAGGGTGAAATCCCTATTTATGAGCCCGGTCTGGATGATA
TGGTAGATGAGTGCATTAAAGCAGGACGTCTCCACTTTACAACCAATATTCAAGAAGGTGTGGAGTTTGGGCTTTACCAA
ATGATTGCTGTTGGCACGCCACCTGATGAGGATGGTTCGGCGGATTTAAGCCATGTGCTTAGTGTGGCGCACAGCATTGG
TAGCTACATGCAGGAGTATCGCATTGTTATTAACAAATCCACCGTGCCTGTTGGTACGGCTGACCTTGTTCGCAATAAAA
TTCGCTCAGTGCTTGCCGAGCGCAATATAGTGCTTGATTTTGATGTGGTTTCCAACCCTGAATTTTTAAAAGAGGGTGAT
GCGGTTGATGACTTTATGAAACCCGATCGCATTATTGTGGGGGTTGATAATCCTCGTACTCGTGAGCTGCTGCGCTTTCT
TTATGCCCCCTTTAACCGTAGCCATGAGCGCTTTATTGCCATGGATATTCGTTCGGCTGAGCTGACCAAGTATGCAGCAA
ACTCCATGCTTGCCACCAAAATTAGCTTTATGAATGAAATTGCCAACATTGCTGATCGCGTTGGTGCCGATGTTGAAGCG
GTACGCAAAGGCATTGGCTCTGACTCGCGTATAGGTTTTTCATTTATTTACCCTGGTATTGGCTACGGAGGTTCATGCTT
TCCAAAAGATGTGCAAGCCTTAGAGCGTACAGCCACCAAACATGGCTACACTGCCCGCTTGTTGCAAGCCGTGGAAGCGG
TGAATGACGACCAAAAAGCCTCGTTGGTAACAAAAATTAAAAACCATTTTAATGGCGACATCAGCGGCAAAATGTTTGCC
TTGTGGGGACTTGCCTTTAAGCCAAACACCGACGATATGCGCGAAGCGCCAAGTCGCCGCATTATTGCCGAATTGCTTGA
GGCTGGTGCTACCGTGCAAGCATATGATCCCGTTGCGATAGAGGAAGCACGTCGTATTTATGGCGATTCCCGTGGCATTC
ACTTTGCCGAAAGCCCTGAGGCAGCCGCACAAGGCGCTGATGCGTTAGTGGTGGTTACAGAGTGGTTGCTCTTCCGTAGC
CCCGATTTTGAAATGCTCAAGCGCGAATTGCGTTCCCCGCTTATTTTTGATGGGCGGAATATTTACAGCCCTGAATTTAT
GGAGCAGGAGGGCTTTACCTACTATTCCATTGGGCGTCCAACCCGTTGCGCACAGTAA

Upstream 100 bases:

>100_bases
GGCTTTTTGTCATTCCCGCAATGGTTACTGAGCGTAGCCGAAGTAAGGCGGGAATCCATGTGTTAGCTGTTTAGTTTTAA
CATTTTAAAAACTACGTGTT

Downstream 100 bases:

>100_bases
GTTTTTAAGATGAGCCACGAGGTAGTTGTTACAATGCTTCGTGGCTTTTTAGTTCCGCTTTTTTTCTACCCTTCTTTTAG
CTGAAGTATTACCCTGTACT

Product: UDP-glucose/GDP-mannose dehydrogenase family protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKITIFGSGYVGLVTGACFAKVGNDVLCVDIDENKINRLRKGEIPIYEPGLDDMVDECIKAGRLHFTTNIQEGVEFGLYQ
MIAVGTPPDEDGSADLSHVLSVAHSIGSYMQEYRIVINKSTVPVGTADLVRNKIRSVLAERNIVLDFDVVSNPEFLKEGD
AVDDFMKPDRIIVGVDNPRTRELLRFLYAPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIADRVGADVEA
VRKGIGSDSRIGFSFIYPGIGYGGSCFPKDVQALERTATKHGYTARLLQAVEAVNDDQKASLVTKIKNHFNGDISGKMFA
LWGLAFKPNTDDMREAPSRRIIAELLEAGATVQAYDPVAIEEARRIYGDSRGIHFAESPEAAAQGADALVVVTEWLLFRS
PDFEMLKRELRSPLIFDGRNIYSPEFMEQEGFTYYSIGRPTRCAQ

Sequences:

>Translated_445_residues
MKITIFGSGYVGLVTGACFAKVGNDVLCVDIDENKINRLRKGEIPIYEPGLDDMVDECIKAGRLHFTTNIQEGVEFGLYQ
MIAVGTPPDEDGSADLSHVLSVAHSIGSYMQEYRIVINKSTVPVGTADLVRNKIRSVLAERNIVLDFDVVSNPEFLKEGD
AVDDFMKPDRIIVGVDNPRTRELLRFLYAPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIADRVGADVEA
VRKGIGSDSRIGFSFIYPGIGYGGSCFPKDVQALERTATKHGYTARLLQAVEAVNDDQKASLVTKIKNHFNGDISGKMFA
LWGLAFKPNTDDMREAPSRRIIAELLEAGATVQAYDPVAIEEARRIYGDSRGIHFAESPEAAAQGADALVVVTEWLLFRS
PDFEMLKRELRSPLIFDGRNIYSPEFMEQEGFTYYSIGRPTRCAQ
>Mature_445_residues
MKITIFGSGYVGLVTGACFAKVGNDVLCVDIDENKINRLRKGEIPIYEPGLDDMVDECIKAGRLHFTTNIQEGVEFGLYQ
MIAVGTPPDEDGSADLSHVLSVAHSIGSYMQEYRIVINKSTVPVGTADLVRNKIRSVLAERNIVLDFDVVSNPEFLKEGD
AVDDFMKPDRIIVGVDNPRTRELLRFLYAPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIADRVGADVEA
VRKGIGSDSRIGFSFIYPGIGYGGSCFPKDVQALERTATKHGYTARLLQAVEAVNDDQKASLVTKIKNHFNGDISGKMFA
LWGLAFKPNTDDMREAPSRRIIAELLEAGATVQAYDPVAIEEARRIYGDSRGIHFAESPEAAAQGADALVVVTEWLLFRS
PDFEMLKRELRSPLIFDGRNIYSPEFMEQEGFTYYSIGRPTRCAQ

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=35.2688172043011, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI296040438, Length=367, Percent_Identity=35.4223433242507, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI296040443, Length=326, Percent_Identity=34.9693251533742, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1788340, Length=365, Percent_Identity=27.1232876712329, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI48994968, Length=364, Percent_Identity=29.6703296703297, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=465, Percent_Identity=33.5483870967742, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI17136908, Length=466, Percent_Identity=34.1201716738197, Blast_Score=243, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49381; Mature: 49381

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIFGSGYVGLVTGACFAKVGNDVLCVDIDENKINRLRKGEIPIYEPGLDDMVDECIK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AGRLHFTTNIQEGVEFGLYQMIAVGTPPDEDGSADLSHVLSVAHSIGSYMQEYRIVINKS
CCCEEEECCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
TVPVGTADLVRNKIRSVLAERNIVLDFDVVSNPEFLKEGDAVDDFMKPDRIIVGVDNPRT
CCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCCCCHHHHCCCCEEEEECCCCCH
RELLRFLYAPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIADRVGADVEA
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDSRIGFSFIYPGIGYGGSCFPKDVQALERTATKHGYTARLLQAVEAVNDDQKA
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
SLVTKIKNHFNGDISGKMFALWGLAFKPNTDDMREAPSRRIIAELLEAGATVQAYDPVAI
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCHHH
EEARRIYGDSRGIHFAESPEAAAQGADALVVVTEWLLFRSPDFEMLKRELRSPLIFDGRN
HHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHCCCCHHHHHHHHCCCEEECCCC
IYSPEFMEQEGFTYYSIGRPTRCAQ
CCCCHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MKITIFGSGYVGLVTGACFAKVGNDVLCVDIDENKINRLRKGEIPIYEPGLDDMVDECIK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AGRLHFTTNIQEGVEFGLYQMIAVGTPPDEDGSADLSHVLSVAHSIGSYMQEYRIVINKS
CCCEEEECCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
TVPVGTADLVRNKIRSVLAERNIVLDFDVVSNPEFLKEGDAVDDFMKPDRIIVGVDNPRT
CCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCCCCHHHHCCCCEEEEECCCCCH
RELLRFLYAPFNRSHERFIAMDIRSAELTKYAANSMLATKISFMNEIANIADRVGADVEA
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDSRIGFSFIYPGIGYGGSCFPKDVQALERTATKHGYTARLLQAVEAVNDDQKA
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
SLVTKIKNHFNGDISGKMFALWGLAFKPNTDDMREAPSRRIIAELLEAGATVQAYDPVAI
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCHHH
EEARRIYGDSRGIHFAESPEAAAQGADALVVVTEWLLFRSPDFEMLKRELRSPLIFDGRN
HHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHCCCCHHHHHHHHCCCEEECCCC
IYSPEFMEQEGFTYYSIGRPTRCAQ
CCCCHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]