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The map label for this gene is phnW2

Identifier: 78067966

GI number: 78067966

Start: 3667890

End: 3669020

Strand: Direct

Name: phnW2

Synonym: Bcep18194_A6497

Alternate gene names: 78067966

Gene position: 3667890-3669020 (Clockwise)

Preceding gene: 78067965

Following gene: 78067967

Centisome position: 99.29

GC content: 68.97

Gene sequence:

>1131_bases
ATGACGCTCGCCGCCCAGCCCATCCTGCTCACCCCCGGCCCCCTGACGACCTCCGACACCACGCGCGACGCGATGCTGCG
CGACTGGGGATCGTGGGACAGCGACTTCAACGCGATCACCGCGCGGCTGCGCGAACGCCTGCTGCAGATCGTGCACGGCG
AAGGCACGCACGAATGCGTCCCGCTGCAAGGCAGCGGCACGTTCTCGGTCGAAGCGGCCATCGGCACGCTCGTGCCGCGC
GACGGCCACGTGCTCGTGCCGAACAACGGCGCGTACTGCCAGCGCATCGCGAAGATCTGCCGCGTGCTCGGCCGCCAGCT
GACGACGATCGACTACAGCGAGGATCGCCGCGTCGATCCGGCCGACGTCGAACGCGCGCTCGCCGCCGATCCGACCATCA
CGCACGTCGCGCTCGTGCACTGCGAAACCGGTGCCGGCGTGCTGAACCCGCTGCATGACATCGCACAGGTCGTCGCGAAG
CACGGCCGTGCGCTGATCGTCGATGCGATGAGCTCGTTCGGCGCGATCGACATCGACGCGCGCACGACGCCGTTCGACGC
GGTGATCGCCGCATCCGGCAAATGCCTCGAAGGCGTACCGGGGCTCGGCTTCGTGATCGCGAAGCGCAGCACGCTCGAAC
GCTGCGAAGGCAACAGCCACTCGCTCGCGATGGACCTGTACGACCAGTGGGTCTACATGCAGCGCACGACGCAGTGGCGC
TTCACGCCGCCGACGCACGTGGTCGCGGCGCTCGACGCCGCCGTCGGGCAATACGTCGACGAGGGCGGGCTCGCTGCTCG
CGGCGGCCGCTACCAGCGCAACTATCGCGCGCTGATCGACGGGATGCTCGCGCTCGGCTTCCGGCCGTTCCTCGATCCGG
CGATCCAGGCGCCGATCATCGTCACGTTCCATGCACCGGACGATCCGAACTACGACTTCAAGCGGTTCTACCAGGAGGTC
AAGAAGCGCGGCTACATCCTGTATCCGGGCAAGCTGACCGAGGTCGAGACGTTCCGGGTCGGCTGCATCGGCCACTTCGG
CGAAGCCGGCATCCCGGGCGCCGTCGCCGCGATCGCCGACACGCTGCGCGCGATGGGTGTGCGCCGCGTGTCGGCCGAAG
CGGCAGCGTGA

Upstream 100 bases:

>100_bases
GCATCGACTGTTGCGCCGCACGCAGGCCTGGCGCAACCCGCATCGCCACTGACTTTTTAGCCGCATTCACGTGACGTCCC
GACTTCATCAAGGAGACACC

Downstream 100 bases:

>100_bases
CGTGACGCACCACGACGTGACGTGATGGTCCCCGCCGCATGCACGTTCGCATGCGGCGGCCGGTGTTTTTCGGGCCGTGC
GCGGCACGGCCCCTTTTCGA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase 2; AEP transaminase 2; AEPT 2

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTLAAQPILLTPGPLTTSDTTRDAMLRDWGSWDSDFNAITARLRERLLQIVHGEGTHECVPLQGSGTFSVEAAIGTLVPR
DGHVLVPNNGAYCQRIAKICRVLGRQLTTIDYSEDRRVDPADVERALAADPTITHVALVHCETGAGVLNPLHDIAQVVAK
HGRALIVDAMSSFGAIDIDARTTPFDAVIAASGKCLEGVPGLGFVIAKRSTLERCEGNSHSLAMDLYDQWVYMQRTTQWR
FTPPTHVVAALDAAVGQYVDEGGLAARGGRYQRNYRALIDGMLALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKRFYQEV
KKRGYILYPGKLTEVETFRVGCIGHFGEAGIPGAVAAIADTLRAMGVRRVSAEAAA

Sequences:

>Translated_376_residues
MTLAAQPILLTPGPLTTSDTTRDAMLRDWGSWDSDFNAITARLRERLLQIVHGEGTHECVPLQGSGTFSVEAAIGTLVPR
DGHVLVPNNGAYCQRIAKICRVLGRQLTTIDYSEDRRVDPADVERALAADPTITHVALVHCETGAGVLNPLHDIAQVVAK
HGRALIVDAMSSFGAIDIDARTTPFDAVIAASGKCLEGVPGLGFVIAKRSTLERCEGNSHSLAMDLYDQWVYMQRTTQWR
FTPPTHVVAALDAAVGQYVDEGGLAARGGRYQRNYRALIDGMLALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKRFYQEV
KKRGYILYPGKLTEVETFRVGCIGHFGEAGIPGAVAAIADTLRAMGVRRVSAEAAA
>Mature_375_residues
TLAAQPILLTPGPLTTSDTTRDAMLRDWGSWDSDFNAITARLRERLLQIVHGEGTHECVPLQGSGTFSVEAAIGTLVPRD
GHVLVPNNGAYCQRIAKICRVLGRQLTTIDYSEDRRVDPADVERALAADPTITHVALVHCETGAGVLNPLHDIAQVVAKH
GRALIVDAMSSFGAIDIDARTTPFDAVIAASGKCLEGVPGLGFVIAKRSTLERCEGNSHSLAMDLYDQWVYMQRTTQWRF
TPPTHVVAALDAAVGQYVDEGGLAARGGRYQRNYRALIDGMLALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKRFYQEVK
KRGYILYPGKLTEVETFRVGCIGHFGEAGIPGAVAAIADTLRAMGVRRVSAEAAA

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=349, Percent_Identity=24.3553008595989, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536281, Length=345, Percent_Identity=24.3478260869565, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW2_BURS3 (Q39BS5)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_370735.1
- ProteinModelPortal:   Q39BS5
- SMR:   Q39BS5
- STRING:   Q39BS5
- GeneID:   3751732
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A6497
- NMPDR:   fig|269483.3.peg.7315
- eggNOG:   COG0075
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- BioCyc:   BSP36773:BCEP18194_A6497-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 40766; Mature: 40635

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00595 AA_TRANSFER_CLASS_5; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAAQPILLTPGPLTTSDTTRDAMLRDWGSWDSDFNAITARLRERLLQIVHGEGTHECV
CCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
PLQGSGTFSVEAAIGTLVPRDGHVLVPNNGAYCQRIAKICRVLGRQLTTIDYSEDRRVDP
EECCCCCEEEEEHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
ADVERALAADPTITHVALVHCETGAGVLNPLHDIAQVVAKHGRALIVDAMSSFGAIDIDA
HHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEECC
RTTPFDAVIAASGKCLEGVPGLGFVIAKRSTLERCEGNSHSLAMDLYDQWVYMQRTTQWR
CCCCCHHHEECCCCHHCCCCCCEEEEECHHHHHHHCCCCCEEEHHHHHHHHEEEECCCEE
FTPPTHVVAALDAAVGQYVDEGGLAARGGRYQRNYRALIDGMLALGFRPFLDPAIQAPII
ECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHCCCEE
VTFHAPDDPNYDFKRFYQEVKKRGYILYPGKLTEVETFRVGCIGHFGEAGIPGAVAAIAD
EEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
TLRAMGVRRVSAEAAA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLAAQPILLTPGPLTTSDTTRDAMLRDWGSWDSDFNAITARLRERLLQIVHGEGTHECV
CCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
PLQGSGTFSVEAAIGTLVPRDGHVLVPNNGAYCQRIAKICRVLGRQLTTIDYSEDRRVDP
EECCCCCEEEEEHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
ADVERALAADPTITHVALVHCETGAGVLNPLHDIAQVVAKHGRALIVDAMSSFGAIDIDA
HHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEECC
RTTPFDAVIAASGKCLEGVPGLGFVIAKRSTLERCEGNSHSLAMDLYDQWVYMQRTTQWR
CCCCCHHHEECCCCHHCCCCCCEEEEECHHHHHHHCCCCCEEEHHHHHHHHEEEECCCEE
FTPPTHVVAALDAAVGQYVDEGGLAARGGRYQRNYRALIDGMLALGFRPFLDPAIQAPII
ECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHCCCEE
VTFHAPDDPNYDFKRFYQEVKKRGYILYPGKLTEVETFRVGCIGHFGEAGIPGAVAAIAD
EEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
TLRAMGVRRVSAEAAA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA