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The map label for this gene is mreB [H]

Identifier: 78067930

GI number: 78067930

Start: 3627487

End: 3628530

Strand: Direct

Name: mreB [H]

Synonym: Bcep18194_A6461

Alternate gene names: 78067930

Gene position: 3627487-3628530 (Clockwise)

Preceding gene: 78067924

Following gene: 78067931

Centisome position: 98.2

GC content: 64.08

Gene sequence:

>1044_bases
ATGTTCGGTTTTTTGCGCAGCTACTTCTCCAACGATCTCGCGATCGACCTCGGCACCGCAAACACCCTGATCTACATGCG
CGGCAAGGGCATCGTGCTCGATGAGCCGTCCGTCGTGTCGATCCGCCAGGAAGGCGGCCCCAACGGCAAGAAGACCATCC
AGGCAGTCGGTAAGGAAGCCAAGCAGATGCTCGGCAAGGTGCCGGGCAACATCGAGGCGATCCGCCCGATGAAGGACGGC
GTGATCGCCGACTTCACCGTCACCGAGCAGATGATCAAGCAGTTCATCAAGACGGCCCACGAGTCGCGCATGTTCTCGCC
GTCGCCGCGCATCATCATCTGCGTGCCGTGCGGCTCGACCCAGGTCGAGCGCCGCGCGATCAAGGAAGCCGCGCACGGCG
CCGGCGCATCGCAGGTCTACCTGATCGAAGAGCCGATGGCCGCTGCGATCGGCGCGGGCCTGCCGGTGTCGGAAGCCACC
GGCTCGATGGTCGTCGACATTGGCGGCGGCACGACGGAAGTCGGCGTGATCTCGCTCGGCGGCATCGTGTACAAGGGTTC
GGTGCGCGTCGGCGGCGACAAGTTCGACGAGGCGATCGTCAACTACATCCGCCGCAACTACGGGATGCTGATCGGCGAAC
AGACCGCCGAAGCGATCAAGAAGGAAATCGGCTCCGCGTTCCCGGGCTCCGAAGTCAAGGAAATGGAAGTGAAGGGCCGC
AACCTGTCGGAAGGCATTCCGCGCAGCTTCACGATCTCCAGCAACGAAATCCTCGAAGCGCTGACCGATCCGCTGAACCA
GATCGTGTCGTCGGTGAAGATCGCGCTCGAACAGACGCCGCCGGAACTCGGCGCCGACATCGCCGAACGCGGGATGATGC
TGACGGGCGGCGGCGCACTGCTGCGCGATCTCGATCGCCTGCTGGCGGAAGAAACCGGCCTGCCGGTGCTCGTCGCGGAA
GATCCGCTCACCTGTGTCGTGCGCGGTTCGGGCATGGCGCTCGAGCGCATGGACAAGCTGGGCAGCATCTTCTCGTACGA
GTGA

Upstream 100 bases:

>100_bases
GGCGGCCGCTTCCGCCACGCTTCCCGAGGCTGTTATTTTTTCCGCTGCCGCCCTCAGCGCTCGCTATGCAGGGCCGGCCC
AGAGCGAAACAGGATTCTGA

Downstream 100 bases:

>100_bases
TCGTCCAGGCAGTCTTCCTGACATGACGCAACCGCGGCGTGGCCGGCTCGCTCGTTTAGAACGAACCGCCGCGCCGTTTG
CGCGTCTGAGCATCATTTAA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGSTQVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR
NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Sequences:

>Translated_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGSTQVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR
NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE
>Mature_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGSTQVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR
NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082236, Length=350, Percent_Identity=71.1428571428571, Blast_Score=506, Evalue=1e-145,
Organism=Escherichia coli, GI1788875, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323401, Length=264, Percent_Identity=25.3787878787879, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36967; Mature: 36967

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
QVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKTIQAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMIKQFIKTAHESRMFSPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
QVERRAIKEAAHGAGASQVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GIVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVKEMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGIPRSFTISSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]