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The map label for this gene is yahK [H]

Identifier: 78067924

GI number: 78067924

Start: 3620828

End: 3621880

Strand: Direct

Name: yahK [H]

Synonym: Bcep18194_A6455

Alternate gene names: 78067924

Gene position: 3620828-3621880 (Clockwise)

Preceding gene: 78067922

Following gene: 78067930

Centisome position: 98.02

GC content: 66.19

Gene sequence:

>1053_bases
ATGAGCACTACCTATGCCTACGCGGCGACCGATTCGCAGTCGCCGCTCGCCCCGTTCGAATTCCAGCGTCGCGCGCTGCG
CGACCTCGACGTCCAGATCGACGTCCTCTACTGCGGCGTCTGCCACTCGGACCTGCACCAGGCCCGCAACGAATGGCGCA
ACACGATCTATCCGGTCGTGCCGGGCCATGAAATCGTCGGCCGCGTGACCGCGACCGGCCCGCAGGTTTCGCGCTTCAAG
GTCGGCGAGCTGGTCGGCGTCGGCTGCCTCGTCGATTCGTGCCGCACCTGCCCGAGCTGCGCCGACGGCCTCGAGCAATA
TTGCGAGAACGGCTTCGTCGGCACCTACAACGGCCAGGATCGCGTGACGGGCGACATCACGTTCGGCGGCTATTCGACGC
AGCTCGTCGTCGACGAGGCGTTCGTGCTGCGCGTGCCCGACACGCTCGACCCGGCCGGCGCCGCACCGCTGCTGTGCGCG
GGGATCACGACCTACTCGCCGCTGCGGCAGTGGAACGTCGGCCCCGGCAAGAAGGTCGGCATCGTCGGGCTCGGCGGCCT
CGGTCACATGGGCGTGAAGCTGGCGCGCGCGATGGGTGCGCACGTCGTGCTGTTCACCACGTCGCCGTCGAAGATCGAGG
ACGGCAAGCGGGTCGGCGCGCACGAAGTCGTGATCTCGAAGGACGAAGCGCAGATGAACGCGCACCTGAACAGCTTCGAC
TTCATCCTGAACACGGTCGCCGCGCAGCACGACCTGAACCCGTTCCTGCACCTGCTGAAGCGCGACGGCACGATGACGCT
GGTCGGCGCGCCGGAGCACGACCATCCGTCGCCGCAGGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTCGCGGGCTCGC
TGATCGGCGGGATCGCGGAAACGCAGGAAATGCTCGACTTCTGCGCGGAGCACGGGATCACGTCGGATATCGAAACGATT
CCGATGCAGCAGATCAACGCGGCCTACGAGCGGATGCTGAAGAGCGACGTGAAGTACCGGTTCGTGATCGACATGGCGTC
GATCAAGCATTGA

Upstream 100 bases:

>100_bases
GCGCCGCGCTCCTTACGATGACGTCCTGCCTCGCCGCATCGCCACATGATGCGACGGCAGTCTGTTTCGCCGGATGCTTT
CCGGACAAGGAGCCCATCGC

Downstream 100 bases:

>100_bases
GCGCCGCCGGGCGGCATGCACGATCGCCGCCCCAAAAAGAAACGGGCCGCATGTTCGACATGCGGCCCGTTTTTGCATCC
GGCGGCCGGACGATCCGGCT

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCPSCADGLEQYCENGFVGTYNGQDRVTGDITFGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRVGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVIDMASIKH

Sequences:

>Translated_350_residues
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCPSCADGLEQYCENGFVGTYNGQDRVTGDITFGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRVGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVIDMASIKH
>Mature_349_residues
STTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFKV
GELVGVGCLVDSCRTCPSCADGLEQYCENGFVGTYNGQDRVTGDITFGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAG
ITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRVGAHEVVISKDEAQMNAHLNSFDF
ILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETIP
MQQINAAYERMLKSDVKYRFVIDMASIKH

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=23.9782016348774, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=23.9782016348774, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501933, Length=364, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=24.4565217391304, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4501929, Length=362, Percent_Identity=24.3093922651934, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786518, Length=340, Percent_Identity=64.1176470588235, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=35.9420289855072, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=26.6871165644172, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=27.9365079365079, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788073, Length=257, Percent_Identity=27.2373540856031, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082125, Length=198, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788407, Length=273, Percent_Identity=25.2747252747253, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790045, Length=273, Percent_Identity=27.1062271062271, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=336, Percent_Identity=27.3809523809524, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562584, Length=339, Percent_Identity=26.8436578171091, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=27.5568181818182, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25146526, Length=329, Percent_Identity=26.1398176291793, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=331, Percent_Identity=25.9818731117825, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=38.0664652567976, Blast_Score=188, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6319949, Length=334, Percent_Identity=34.1317365269461, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=33.8461538461538, Blast_Score=155, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=32.9230769230769, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319621, Length=324, Percent_Identity=31.1728395061728, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323729, Length=324, Percent_Identity=29.9382716049383, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=314, Percent_Identity=26.1146496815287, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=380, Percent_Identity=25.7894736842105, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737895, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38175; Mature: 38044

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVV
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCPSCADGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCC
RVTGDITFGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCCEEEEEEECEEEEECCCCCCCCCCCCHHHHCCCCCCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRVGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVIDMASIKH
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEEHHCCC
>Mature Secondary Structure 
STTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVV
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCPSCADGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCC
RVTGDITFGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCCEEEEEEECEEEEECCCCCCCCCCCCHHHHCCCCCCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRVGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVIDMASIKH
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]