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The map label for this gene is argB [H]

Identifier: 78067916

GI number: 78067916

Start: 3612650

End: 3613549

Strand: Direct

Name: argB [H]

Synonym: Bcep18194_A6447

Alternate gene names: 78067916

Gene position: 3612650-3613549 (Clockwise)

Preceding gene: 78067915

Following gene: 78067917

Centisome position: 97.79

GC content: 63.56

Gene sequence:

>900_bases
ATGTCCGAGCCCATCGACCTCTCGCAGATCGCCCCCACGCTGAAAGCAGAAATCCTCGCCGAGGCACTGCCGTACATTCG
CCGTTACCACGGCAAGACCGTGGTCATCAAATACGGCGGCAACGCGATGACGGAAGAGCGGCTCAAGCAAGGCTTCGCGC
GCGACGTGATCCTGCTGAAACTGGTCGGCATCAATCCGGTGATCGTCCACGGCGGCGGTCCGCAGATCGATCACGCACTG
AAGAAGATCGGCAAGGCCGGCACCTTCATCCAGGGCATGCGCGTCACCGACGAAGAGACGATGGAAGTCGTCGAATGGGT
GCTGGGCGGCGAAGTGCAGCAGGACATCGTGATGCTGATCAACCACTTCGGCGGCCACGCGGTGGGCCTGACGGGCAAGG
ACGGCGGCCTGATCCACGCGCGCAAGCTGCTGATGCCGGACCGCGACAACCCGGGCCAGTACATCGACATCGGCCAGGTC
GGCGAAGTCGAGGCGATCAACCCGGCGGTCGTGAAGGCGCTGCAGGACGACGCATTCATCCCGGTGATCTCGCCGATCGG
TTTCGGTGAAGACGGCCTCTCGTACAACATCAACGCCGACCTCGTCGCAGGCAAGCTCGCCACCGTGCTGAACGCCGAGA
AGCTGCTGATGATGACCAACATCCCGGGCGTGATGGACAAGGACGGCAACCTGCTGACCGACCTGTCCGCGCGCGAGATC
GACGCACTGTTCGAAGACGGCACGATCTCCGGCGGCATGCTGCCGAAGATCTCGTCGGCGCTCGACGCGGCGAAGAGCGG
CGTGAAGTCGGTGCACATCGTCGACGGCCGGATCGAGCACTCGGTGCTGCTGGAAATCCTGACCGAGCAGCCGTTCGGCA
CGATGATCCGCTCGCATTGA

Upstream 100 bases:

>100_bases
GCGCCGCCGGTGTTCCGGCCCGCCCAAAAACCCGATGCTGCGCTGCGCCACTCCTGTACAATTCGCCGTGTTTCAACCGT
TCCCAGCCTGAGCCGCCGCC

Downstream 100 bases:

>100_bases
GCACCCGCAGCAAGACCGCCACACCCGACTTGCCGGCCCCGCTGCGGCGCCGGCGCGTGTCGCGCAGCCGGCCCCGCGCC
GGCGCGCCGGTGTGGCTGTT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHAL
KKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQV
GEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREI
DALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH

Sequences:

>Translated_299_residues
MSEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHAL
KKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQV
GEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREI
DALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
>Mature_298_residues
SEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHALK
KIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQVG
EVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREID
ALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=28.2685512367491, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI145693208, Length=264, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=270, Percent_Identity=27.037037037037, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 32111; Mature: 31980

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEE
LVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLI
EECCCEEEEECCCCCHHHHHHHHCCCCCEEECEECCCHHHHHHHHHHHCCCHHHHHHHHH
NHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQVGEVEAINPAVVKALQDDAFI
HHCCCEEEEECCCCCCEEEEEHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCE
PVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREI
EEECCCCCCCCCCEEECCHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEECCCHHHH
DALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SEPIDLSQIAPTLKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEE
LVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLI
EECCCEEEEECCCCCHHHHHHHHCCCCCEEECEECCCHHHHHHHHHHHCCCHHHHHHHHH
NHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQVGEVEAINPAVVKALQDDAFI
HHCCCEEEEECCCCCCEEEEEHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCE
PVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREI
EEECCCCCCCCCCEEECCHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEECCCHHHH
DALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA