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The map label for this gene is csgA [H]

Identifier: 78067740

GI number: 78067740

Start: 3433513

End: 3434190

Strand: Direct

Name: csgA [H]

Synonym: Bcep18194_A6271

Alternate gene names: 78067740

Gene position: 3433513-3434190 (Clockwise)

Preceding gene: 78067739

Following gene: 78067741

Centisome position: 92.95

GC content: 70.06

Gene sequence:

>678_bases
ATGAAAACCGCATTGATCGTCGGTGCATCGCGCGGCCTCGGCCGCGAATTCGTCCGCCAATACCGGCGCGACGGCTGGAA
CGTGATCGCCACCGCGCGCGACGACGCGTCGCTCGACGCGCTACGCGCGCTCGGTGCGCACGCGCATGCGCTCGACATCA
CGCAGCCCGAGCAGATCGCGGCGCTCGGCTGGAAACTCGACGGCGAGCGGCTCGATGCGGCCGTGCTGGTGTCGGGTGTG
TACGGGCCGCGCACCGAGGGCGTCGAGACGGTCACCGCCGAGGATTTCGACGCGGTGATGCATACGAACGTGCGCGGGCC
GATGCAATTGCTGCCGATCGTGCTGCCGCTGGTCGAGGACGCGCGCGGCGTGCTGGCCGTCGTGTCGAGCCGGATGGGCA
GCATCGCCGAGGCGACCGGCACGACCGGCTGGCTGTACCGCGCGAGCAAGGCCGCGCTGAACGACGCGCTGCGCATCGCG
TCGCTGCAGACGCGCCATGCCGCCTGTATCTCGCTCCATCCCGGCTGGGTGCGCACCGACATGGGCGGCGCGCAGGCCGC
GATCGACCCGGAAACCAGCGTGACCGGCATGCGCCGCGTGATCGCCGAATCCGGCGCGGACGTGTCGCAGGCAAACGGCC
GTTTCTTCCAGTACGACGGTATCGAGCTGAGCTGGTAG

Upstream 100 bases:

>100_bases
GCACGGCGGCCGCTGCGCAGGCGTACAGTCGTGCCACCCCTCGAATGGATCTGATCCCGGCGCTGCCGCCACGGCGGCGC
CAAGCAAAGGAGCGACGCGC

Downstream 100 bases:

>100_bases
GCAGCCGACAACCTTGCGTCGTTAATTCCCGATTCGCATGATTTCGAACCGACCTGACGCGTGCCCGTGCGGCGGCGCGT
CCCCCGCTCCCGCCGGCAAA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTALIVGASRGLGREFVRQYRRDGWNVIATARDDASLDALRALGAHAHALDITQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETVTAEDFDAVMHTNVRGPMQLLPIVLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESGADVSQANGRFFQYDGIELSW

Sequences:

>Translated_225_residues
MKTALIVGASRGLGREFVRQYRRDGWNVIATARDDASLDALRALGAHAHALDITQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETVTAEDFDAVMHTNVRGPMQLLPIVLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESGADVSQANGRFFQYDGIELSW
>Mature_225_residues
MKTALIVGASRGLGREFVRQYRRDGWNVIATARDDASLDALRALGAHAHALDITQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETVTAEDFDAVMHTNVRGPMQLLPIVLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESGADVSQANGRFFQYDGIELSW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=30.1652892561983, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193207563, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558992, Length=246, Percent_Identity=29.6747967479675, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=29.4820717131474, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24080; Mature: 24080

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTALIVGASRGLGREFVRQYRRDGWNVIATARDDASLDALRALGAHAHALDITQPEQIA
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEECCCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETVTAEDFDAVMHTNVRGPMQLLPIVLPLVED
HCCEEECCHHHCHHHEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAESGADVSQANGRFFQYDGIELSW
CCCCCEECCCCHHHHHHHHHHHHCCCCCHHCCCCEEEECCEEECC
>Mature Secondary Structure
MKTALIVGASRGLGREFVRQYRRDGWNVIATARDDASLDALRALGAHAHALDITQPEQIA
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEECCCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETVTAEDFDAVMHTNVRGPMQLLPIVLPLVED
HCCEEECCHHHCHHHEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAESGADVSQANGRFFQYDGIELSW
CCCCCEECCCCHHHHHHHHHHHHCCCCCHHCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]