Click here to switch to the map view.

The map label for this gene is can [H]

Identifier: 78067739

GI number: 78067739

Start: 3432634

End: 3433401

Strand: Direct

Name: can [H]

Synonym: Bcep18194_A6270

Alternate gene names: 78067739

Gene position: 3432634-3433401 (Clockwise)

Preceding gene: 78067738

Following gene: 78067740

Centisome position: 92.92

GC content: 66.41

Gene sequence:

>768_bases
ATGAACACCCAAGACCATCCGCTTTCACACCTGTTCGACAACAACGACGCCTGGGTCAAGCACAAGCTCGAAGACGACCC
GCAATTCTTCGCGCGTCTGGCCGACCAGCAGGCGCCGGAGTATCTGTGGATCGGCTGCTCGGATTCGCGCGTGCCCGCGA
ACGAGATCATCGGCCTGCCGCCGGGCGAAGTGTTCGTCCACCGCAATATCGCGAACGTGGTCGTGCACAGCGACCTGAAC
TGCCTGTCGGTGATCCAGTTCGCGGTCGACATCCTGCGCGTGAAGCACATCATGGTCGTCGGCCACTACGGCTGCTCGGG
CGTGAACGCCGCGCTGCTCAACCGTCGCGTCGGCCTCGCCGACAACTGGCTGCATCACGTGCAGGACGTGCGCGAGCGCC
ACACGGCGCTGCTCGACGCATGGCCGGTGGGCGAAGCGCGCTATCGCCGCCTGATCGAGCTGAACGCGATCGAGCAGGTG
GTCAACGTGTGCCGCACGACGATCGTCAACGACGCGTGGGCGCGCGGCCAGTCGCTCACCGTGCACGGGCTCGTGTACGG
CGTGCACGACGGCCGGATGCGCAACCTCGGGATGGCCGTGTCGAACTTCGAAGCGCTCGACGAGACCTACACGCGTTGCG
TGGCCGCACTCGTCGCCGGCGGCGAGCATGCGCCGGACAATGACATGATCGCGGCAGACGCCGCACGGCTCGAAGGCGTC
GCGCAGGCTGTCGCCGCCACGCTGAAGCCGTGCGACGACGCGAAGTAA

Upstream 100 bases:

>100_bases
ACGGACCAGAACGATGGCGCAGGCGACGCGCAGCGCGCCGCCTGACGCCCGCTACACCGCACCGATTGCGACCTGATTTC
CGCCAACGGAATCCACACCG

Downstream 100 bases:

>100_bases
CGCCACGGCCTGCACGGCGGCCGCTGCGCAGGCGTACAGTCGTGCCACCCCTCGAATGGATCTGATCCCGGCGCTGCCGC
CACGGCGGCGCCAAGCAAAG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNTQDHPLSHLFDNNDAWVKHKLEDDPQFFARLADQQAPEYLWIGCSDSRVPANEIIGLPPGEVFVHRNIANVVVHSDLN
CLSVIQFAVDILRVKHIMVVGHYGCSGVNAALLNRRVGLADNWLHHVQDVRERHTALLDAWPVGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMAVSNFEALDETYTRCVAALVAGGEHAPDNDMIAADAARLEGV
AQAVAATLKPCDDAK

Sequences:

>Translated_255_residues
MNTQDHPLSHLFDNNDAWVKHKLEDDPQFFARLADQQAPEYLWIGCSDSRVPANEIIGLPPGEVFVHRNIANVVVHSDLN
CLSVIQFAVDILRVKHIMVVGHYGCSGVNAALLNRRVGLADNWLHHVQDVRERHTALLDAWPVGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMAVSNFEALDETYTRCVAALVAGGEHAPDNDMIAADAARLEGV
AQAVAATLKPCDDAK
>Mature_255_residues
MNTQDHPLSHLFDNNDAWVKHKLEDDPQFFARLADQQAPEYLWIGCSDSRVPANEIIGLPPGEVFVHRNIANVVVHSDLN
CLSVIQFAVDILRVKHIMVVGHYGCSGVNAALLNRRVGLADNWLHHVQDVRERHTALLDAWPVGEARYRRLIELNAIEQV
VNVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMAVSNFEALDETYTRCVAALVAGGEHAPDNDMIAADAARLEGV
AQAVAATLKPCDDAK

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=207, Percent_Identity=52.1739130434783, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786534, Length=213, Percent_Identity=27.2300469483568, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=191, Percent_Identity=28.7958115183246, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 28163; Mature: 28163

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQDHPLSHLFDNNDAWVKHKLEDDPQFFARLADQQAPEYLWIGCSDSRVPANEIIGLP
CCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCC
PGEVFVHRNIANVVVHSDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALLNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCH
DNWLHHVQDVRERHTALLDAWPVGEARYRRLIELNAIEQVVNVCRTTIVNDAWARGQSLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHGLVYGVHDGRMRNLGMAVSNFEALDETYTRCVAALVAGGEHAPDNDMIAADAARLEGV
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHH
AQAVAATLKPCDDAK
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTQDHPLSHLFDNNDAWVKHKLEDDPQFFARLADQQAPEYLWIGCSDSRVPANEIIGLP
CCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCC
PGEVFVHRNIANVVVHSDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALLNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCH
DNWLHHVQDVRERHTALLDAWPVGEARYRRLIELNAIEQVVNVCRTTIVNDAWARGQSLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHGLVYGVHDGRMRNLGMAVSNFEALDETYTRCVAALVAGGEHAPDNDMIAADAARLEGV
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHH
AQAVAATLKPCDDAK
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]