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The map label for this gene is gpmA

Identifier: 78067655

GI number: 78067655

Start: 3332443

End: 3333255

Strand: Direct

Name: gpmA

Synonym: Bcep18194_A6186

Alternate gene names: 78067655

Gene position: 3332443-3333255 (Clockwise)

Preceding gene: 78067649

Following gene: 78067656

Centisome position: 90.21

GC content: 66.54

Gene sequence:

>813_bases
ATGGCGGGCCCGGGTCGGGTCCTGCTCGACGCGCCACAGCTTCCTTCACTACCGACCGCAAGATCCATGTACAAACTCGT
TCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGACGTCGACCTGACCGAACAGG
GTCGCAACGAGGCCTACCAGGCCGGCGAATTGCTCAAGGAGGCCGGCTACACGTTCGACATCGCGTACACGTCGGTGCTC
AAGCGCGCGATCCGCACGCTGTGGCACGTGCAGGACAAGATGGACCTGATGTACCTGCCGGTCGTCCACTCGTGGCGCCT
GAACGAGCGCCACTACGGCGCGCTGTCGGGCCTGAACAAGGCGGAAACGGCCGCGAAGTTCGGCGACGACCAGGTGCTCG
TGTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTCGAGGCGACCGACGAACGCGCGCCGTTCAACGACCCGCGCTAC
GCGAAGGTGCCGCGCGAGCAACTGCCGCTCACCGAGTGCCTGAAGGACACGGTCGCGCGCGTGCTGCCGCTGTGGAACGA
GTCGATCGCCCCGGCGGTCCGCGCCGGCAAGCAGGTGCTGATCGCCGCGCACGGCAACTCGCTGCGCGCGTTGATCAAGT
ACCTCGACGGCATCTCGGACAGCGACATCGTCGGCCTGAACATCCCGAACGGCGTGCCGCTCGTGTATGAGCTCGACGAA
AACCTGAAGCCGATCAAGCACTATTACCTCGGCGACCAGGACGCGATCGCGCAGGCGCAAGCCGCCGTCGCGAAGCAGGG
CAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCAGGTTGGTGTAATCGGTAAAGAACGTCACGGAATTCCGCCGGAAAAAGAGAAATCGGATGAGGACAATCCCGCCATTA
TAAAATAACCGTCTTGCGCG

Downstream 100 bases:

>100_bases
CGCCCGTCGGCCGGGTGAGCCGGGTGAGCCGCGTCCGGTGCGGCCCGCCCGGCCCCGGCCCTTGCCCGGCGCACCGCGCG
AACCTTCGCGGCCCCGGCGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAGPGRVLLDAPQLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEATDERAPFNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG

Sequences:

>Translated_270_residues
MAGPGRVLLDAPQLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEATDERAPFNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
>Mature_269_residues
AGPGRVLLDAPQLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLK
RAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEATDERAPFNDPRYA
KVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEN
LKPIKHYYLGDQDAIAQAQAAVAKQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=254, Percent_Identity=56.6929133858268, Blast_Score=308, Evalue=4e-84,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=60.6425702811245, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=59.0361445783133, Blast_Score=290, Evalue=9e-79,
Organism=Homo sapiens, GI4502445, Length=253, Percent_Identity=50.9881422924901, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI40353764, Length=253, Percent_Identity=50.9881422924901, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.3456790123457, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1786970, Length=248, Percent_Identity=65.3225806451613, Blast_Score=334, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=54.4715447154472, Blast_Score=251, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6324516, Length=291, Percent_Identity=32.6460481099656, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=298, Percent_Identity=32.5503355704698, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24646216, Length=253, Percent_Identity=51.7786561264822, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=52.4, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=52.4, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=52.4, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI28571815, Length=248, Percent_Identity=40.3225806451613, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=40.6374501992032, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24648979, Length=248, Percent_Identity=40.3225806451613, Blast_Score=181, Evalue=6e-46,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 30115; Mature: 29983

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPGRVLLDAPQLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCCEEEECCCCCCCCCHHHHHEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECEECCEECCCCHHHHHHCCCH
AETAAKFGDDQVLVWRRSYDTPPPALEATDERAPFNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGPGRVLLDAPQLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCEEEECCCCCCCCCHHHHHEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECEECCEECCCCHHHHHHCCCH
AETAAKFGDDQVLVWRRSYDTPPPALEATDERAPFNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA